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Protein
Submitted name:

LIM/homeobox protein Lhx6

Gene

Lhx6

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
LIM/homeobox protein Lhx6Imported
Gene namesi
Name:Lhx6Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:1306803. Lhx6.

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiE9QN32.

Expressioni

Gene expression databases

BgeeiENSMUSG00000026890.
ExpressionAtlasiE9QN32. baseline and differential.
GenevisibleiE9QN32. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000108584.

Structurei

3D structure databases

ProteinModelPortaliE9QN32.
SMRiE9QN32. Positions 98-306.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini97 – 15761LIM zinc-bindingInterPro annotationAdd
BLAST
Domaini158 – 22063LIM zinc-bindingInterPro annotationAdd
BLAST
Domaini246 – 30661Homeobox DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 2 LIM zinc-binding domains.UniRule annotation
Contains homeobox DNA-binding domain.SAAS annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotation, LIM domainUniRule annotationSAAS annotation, RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG0490. Eukaryota.
ENOG410YIJ3. LUCA.
GeneTreeiENSGT00760000118921.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
2.10.110.10. 2 hits.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR001781. Znf_LIM.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00412. LIM. 2 hits.
[Graphical view]
SMARTiSM00389. HOX. 1 hit.
SM00132. LIM. 2 hits.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00478. LIM_DOMAIN_1. 2 hits.
PS50023. LIM_DOMAIN_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9QN32-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYWKHESAAP ALPEGCRLPA EGGPTTDQVM AQPGSGCKAT TRCLEGTAPP
60 70 80 90 100
AMAQSDAEAL AGALDKDEGR ASPCTPSTPS VCSPPSAASS VPSAGKNICS
110 120 130 140 150
SCGLEILDRY LLKVNNLIWH VRCLECSVCR TSLRQQNSCY IKNKEIYCKM
160 170 180 190 200
DYFSRFGTKC ARCGRQIYAS DWVRRARGNA YHLACFACFS CKRQLSTGEE
210 220 230 240 250
FGLVEEKVLC RIHYDTMIEN LKRAAENGNG LTLEGAVPSE QDSQPKPAKR
260 270 280 290 300
ARTSFTAEQL QVMQAQFAQD NNPDAQTLQK LADMTGLSRR VIQVWFQNCR
310 320 330 340 350
ARHKKHTPQH PVPPSGAPPT RLPSALSDDI HYSPFSSPER ARMVTLHGYI
360 370
ESHPFSVLTL PALAHLSMGT TQLPLSR
Length:377
Mass (Da):41,361
Last modified:April 5, 2011 - v1
Checksum:iAD40D809E44B8902
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL773525 Genomic DNA. No translation available.
RefSeqiNP_001076594.1. NM_001083125.1.
UniGeneiMm.12881.

Genome annotation databases

EnsembliENSMUST00000112967; ENSMUSP00000108591; ENSMUSG00000026890.
GeneIDi16874.
UCSCiuc008jlg.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL773525 Genomic DNA. No translation available.
RefSeqiNP_001076594.1. NM_001083125.1.
UniGeneiMm.12881.

3D structure databases

ProteinModelPortaliE9QN32.
SMRiE9QN32. Positions 98-306.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000108584.

Proteomic databases

PaxDbiE9QN32.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000112967; ENSMUSP00000108591; ENSMUSG00000026890.
GeneIDi16874.
UCSCiuc008jlg.1. mouse.

Organism-specific databases

CTDi26468.
MGIiMGI:1306803. Lhx6.

Phylogenomic databases

eggNOGiKOG0490. Eukaryota.
ENOG410YIJ3. LUCA.
GeneTreeiENSGT00760000118921.

Miscellaneous databases

ChiTaRSiLhx6. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000026890.
ExpressionAtlasiE9QN32. baseline and differential.
GenevisibleiE9QN32. MM.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
2.10.110.10. 2 hits.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR001781. Znf_LIM.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00412. LIM. 2 hits.
[Graphical view]
SMARTiSM00389. HOX. 1 hit.
SM00132. LIM. 2 hits.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00478. LIM_DOMAIN_1. 2 hits.
PS50023. LIM_DOMAIN_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE9QN32_MOUSE
AccessioniPrimary (citable) accession number: E9QN32
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 7, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.