Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Probable 28S rRNA (cytosine-C(5))-methyltransferase

Gene

Nop2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei401S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei428S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei445S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei502NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotation, RNA-bindingPROSITE-ProRule annotation, Transferase
LigandS-adenosyl-L-methioninePROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Probable 28S rRNA (cytosine-C(5))-methyltransferaseImported
Gene namesi
Name:Nop2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:107891 Nop2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiE9QN31
PeptideAtlasiE9QN31
PRIDEiE9QN31

Expressioni

Gene expression databases

BgeeiENSMUSG00000038279
ExpressionAtlasiE9QN31 baseline and differential
GenevisibleiE9QN31 MM

Structurei

3D structure databases

ProteinModelPortaliE9QN31
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini285 – 572SAM_MT_RSMB_NOPInterPro annotationAdd BLAST288

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni377 – 383S-adenosyl-L-methionine bindingPROSITE-ProRule annotation7

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1122 Eukaryota
COG0144 LUCA
GeneTreeiENSGT00660000095341
KOiK14835
OMAiAGEMEQD
OrthoDBiEOG091G0685
TreeFamiTF105660

Family and domain databases

InterProiView protein in InterPro
IPR018314 Fmu/NOL1/Nop2p_CS
IPR031341 Methyltr_RsmF_N
IPR001678 MeTrfase_RsmB/NOP2
IPR011023 Nop2p
IPR012586 P120R_rpt
IPR023267 RCMT
IPR023273 RCMT_NOP2
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF01189 Methyltr_RsmB-F, 1 hit
PF17125 Methyltr_RsmF_N, 1 hit
PF08062 P120R, 2 hits
PRINTSiPR02008 RCMTFAMILY
PR02012 RCMTNOP2
SUPFAMiSSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00446 nop2p, 1 hit
PROSITEiView protein in PROSITE
PS01153 NOL1_NOP2_SUN, 1 hit
PS51686 SAM_MT_RSMB_NOP, 1 hit

Sequencei

Sequence statusi: Complete.

E9QN31-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRKLDPTKK EKRGPGRKAR KQKGAETELV RFLPAAGDEN SKRLSSRARK
60 70 80 90 100
RAAKRRAGSV DVPKPNKSPG IKTLPGELSK GAVQARGKKR PAPIQNSDGD
110 120 130 140 150
EEEDSGEDDV VTQGDLWGSE DSDEDMVDDY GAASNSEDEE EKLLPIERAA
160 170 180 190 200
LKQKAQDATA GVLWNEEDTD EDEDDDGVSP ESHPRKDDKA EGDLQINVED
210 220 230 240 250
EEAFVLPPAG ETDQDGQAPD LQRVHKRIQD IVGVLRDFGA QREEGRSRAE
260 270 280 290 300
YLSRLQKDLA TYYSYGDFLL SKLMELFPLS ELIEFLEANE VPRPITLRTN
310 320 330 340 350
TLKTRRRDLA QALINRGVNL DPLGKWSKSG LVVYDSSVPI GATPEYLAGH
360 370 380 390 400
YMLQGASSML PVMALAPQEH ERILDMCCAP GGKTSYIAQL MKNTGVILAN
410 420 430 440 450
DANADRLKSV VGNLHRLGVT NTIISHYDGR QFPKVVGGFD RVLLDAPCSG
460 470 480 490 500
TGVISKDPAV KTNKDEKDIQ RCAHLQKELL LSAIDSVNAA SKTGGYLVYC
510 520 530 540 550
TCSITVEENE WVVDYALKKR NVRLVPTGLD FGQEGFTRFQ ARRFHPTLRS
560 570 580 590 600
TRRFYPHTHN MDGFFIAKFK KFSNSIPQPH AGNSAAATPT EPDLKDQVTP
610 620 630 640 650
KSENGSQPTK KARGAVKAKQ QLLRQPHSKK PFQKLNGIAK GPGLSTEPSV
660 670 680 690 700
PDAQVSTRPS QSAGNADVNS KRKRSEKLKQ RGPKWKPSKE AAVPKPSAPS
710 720 730 740 750
RVEDSRTPPV PTPSEIRAAP RPKDCAPSLG EAKKKQKGKQ QLAQQPANGA
760 770 780 790
APLKEDAVSK GPSAPFVSPH SSTRPPPAKR RKSMTKGNSQ PLLS
Length:794
Mass (Da):86,907
Last modified:April 5, 2011 - v1
Checksum:i1520EFF0D1854C3C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC166162 Genomic DNA No translation available.
RefSeqiNP_620086.2, NM_138747.2
UniGeneiMm.29203

Genome annotation databases

EnsembliENSMUST00000044200; ENSMUSP00000047123; ENSMUSG00000038279
GeneIDi110109
KEGGimmu:110109
UCSCiuc009dtn.2 mouse

Similar proteinsi

Entry informationi

Entry nameiE9QN31_MOUSE
AccessioniPrimary (citable) accession number: E9QN31
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 23, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health