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Protein
Submitted name:

Protein Adgre5

Gene

Adgre5

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-373080. Class B/2 (Secretin family receptors).
R-MMU-6798695. Neutrophil degranulation.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Adgre5Imported
Gene namesi
Name:Adgre5Imported
Synonyms:Cd97Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:1347095. Adgre5.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei490 – 509HelicalSequence analysisAdd BLAST20
Transmembranei521 – 538HelicalSequence analysisAdd BLAST18
Transmembranei550 – 582HelicalSequence analysisAdd BLAST33
Transmembranei594 – 611HelicalSequence analysisAdd BLAST18
Transmembranei631 – 655HelicalSequence analysisAdd BLAST25
Transmembranei676 – 699HelicalSequence analysisAdd BLAST24
Transmembranei705 – 728HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_500324480929 – 773Sequence analysisAdd BLAST745

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

MaxQBiE9QMJ5.
PRIDEiE9QMJ5.

Expressioni

Gene expression databases

BgeeiENSMUSG00000002885.
ExpressionAtlasiE9QMJ5. baseline and differential.
GenevisibleiE9QMJ5. MM.

Structurei

3D structure databases

ProteinModelPortaliE9QMJ5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini69 – 107EGF-likeInterPro annotationAdd BLAST39
Domaini120 – 158EGF-likeInterPro annotationAdd BLAST39
Domaini169 – 207EGF-likeInterPro annotationAdd BLAST39
Domaini434 – 479GPSInterPro annotationAdd BLAST46
Domaini484 – 729G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST246

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

EGF-like domainSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00830000128227.

Family and domain databases

InterProiIPR001881. EGF-like_Ca-bd_dom.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR017981. GPCR_2-like.
IPR003056. GPCR_2_CD97.
IPR000832. GPCR_2_secretin-like.
IPR000203. GPS.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF07645. EGF_CA. 3 hits.
PF01825. GPS. 1 hit.
[Graphical view]
PRINTSiPR01278. CD97PROTEIN.
PR00249. GPCRSECRETIN.
SMARTiSM00181. EGF. 4 hits.
SM00179. EGF_CA. 3 hits.
SM00303. GPS. 1 hit.
[Graphical view]
PROSITEiPS00010. ASX_HYDROXYL. 3 hits.
PS50026. EGF_3. 3 hits.
PS01187. EGF_CA. 3 hits.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9QMJ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGVRCPGLL VVCILLSLSG AGTQKAESKN CAKWCPINSK CVSNRSCVCK
60 70 80 90 100
PGFSSEKELI TNPAESCEDI NECLLPGFSC GDFAMCKNSE GSYTCVCNLG
110 120 130 140 150
YKLLSGAESF VNESENTCQD VNECISGQNH CHQSTHCINK LGGYSCICRQ
160 170 180 190 200
GWKPVPGSPN GPVSTVCEDV DECSSGQHQC HNSTVCKNTV GSYKCHCRPG
210 220 230 240 250
WKPTSGSLRG PDTICQEPPF PTWTLLPTAH SQTLLRFSVE VQNLLRDFNP
260 270 280 290 300
ATVNYTIQKL IEAVDKLLED PMETETQQVA AQLLSNLEQS LRTLAQFLPK
310 320 330 340 350
GPFTYTSPSN TELSLMVKEQ DNKDVTTVHH GQTWMELDWA VTAGAKISEN
360 370 380 390 400
GSSVAGILSS PNMEKLLGNT PLNLEQRRAS LEDFYGSPIP SVSLKLLSNI
410 420 430 440 450
NSVFLTNTNT EKLASNVTFK FDFTSVESIE PRHELICAFW KAHNGNGYWD
460 470 480 490 500
TDGCSMNGTG FCHCNHLTSF AILMAQYHVQ DPRLELITKV GLLLSLICLL
510 520 530 540 550
LCILTFLLVK PIQSSRTMVH LHLCICLFLG SIIFLVGVEN EGGEVGLRCR
560 570 580 590 600
LVAVMLHFCF LAAFCWMALE GVELYFLVVR VFQGQGLSTW QRCLIGYGVP
610 620 630 640 650
LLIVAISMAV VKMDGYGHAT YCWLDFRKQG FLWSFSGPVA FIIFCNAAIF
660 670 680 690 700
VITVWKLTKK FSEINPNMKK LRKARVLTIT SIAQLLVLGC TWGFGLFLFN
710 720 730 740 750
PHSTWLSYIF TLLNCLQGLF LYVMLCLLNK KVREEYWKWA CMVTGSKYTE
760 770
FNSSTTGTGT SQTRALRSSE SGM
Length:773
Mass (Da):85,642
Last modified:April 5, 2011 - v1
Checksum:i92C0A0F9FC11F68F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC164432 Genomic DNA. No translation available.
RefSeqiNP_001156502.1. NM_001163030.1.
UniGeneiMm.334648.

Genome annotation databases

EnsembliENSMUST00000109802; ENSMUSP00000105427; ENSMUSG00000002885.
GeneIDi26364.
UCSCiuc012ggt.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC164432 Genomic DNA. No translation available.
RefSeqiNP_001156502.1. NM_001163030.1.
UniGeneiMm.334648.

3D structure databases

ProteinModelPortaliE9QMJ5.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

MaxQBiE9QMJ5.
PRIDEiE9QMJ5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000109802; ENSMUSP00000105427; ENSMUSG00000002885.
GeneIDi26364.
UCSCiuc012ggt.1. mouse.

Organism-specific databases

CTDi976.
MGIiMGI:1347095. Adgre5.

Phylogenomic databases

GeneTreeiENSGT00830000128227.

Enzyme and pathway databases

ReactomeiR-MMU-373080. Class B/2 (Secretin family receptors).
R-MMU-6798695. Neutrophil degranulation.

Miscellaneous databases

ChiTaRSiCd97. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000002885.
ExpressionAtlasiE9QMJ5. baseline and differential.
GenevisibleiE9QMJ5. MM.

Family and domain databases

InterProiIPR001881. EGF-like_Ca-bd_dom.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR017981. GPCR_2-like.
IPR003056. GPCR_2_CD97.
IPR000832. GPCR_2_secretin-like.
IPR000203. GPS.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF07645. EGF_CA. 3 hits.
PF01825. GPS. 1 hit.
[Graphical view]
PRINTSiPR01278. CD97PROTEIN.
PR00249. GPCRSECRETIN.
SMARTiSM00181. EGF. 4 hits.
SM00179. EGF_CA. 3 hits.
SM00303. GPS. 1 hit.
[Graphical view]
PROSITEiPS00010. ASX_HYDROXYL. 3 hits.
PS50026. EGF_3. 3 hits.
PS01187. EGF_CA. 3 hits.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE9QMJ5_MOUSE
AccessioniPrimary (citable) accession number: E9QMJ5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 30, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.