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Protein
Submitted name:

Insulin-like growth factor II

Gene

Igf2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin-like growth factor IIImported
Gene namesi
Name:Igf2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:96434. Igf2.

Subcellular locationi

  • Secreted UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

SecretedUniRule annotationSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 35Sequence analysisAdd BLAST35
ChainiPRO_500324333436 – 191Sequence analysisAdd BLAST156

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

MaxQBiE9QLW5.
PaxDbiE9QLW5.
PeptideAtlasiE9QLW5.
PRIDEiE9QLW5.

PTM databases

iPTMnetiE9QLW5.

Expressioni

Gene expression databases

BgeeiENSMUSG00000048583.
ExpressionAtlasiE9QLW5. baseline and differential.
GenevisibleiE9QLW5. MM.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliE9QLW5.
SMRiE9QLW5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 95IlGFInterPro annotationAdd BLAST55

Sequence similaritiesi

Belongs to the insulin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IY3P. Eukaryota.
ENOG4111KP2. LUCA.
GeneTreeiENSGT00530000063856.
OMAiFPRYPVG.
OrthoDBiEOG091G0H56.

Family and domain databases

Gene3Di1.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR022334. IGF2.
IPR013576. IGF2_C.
IPR016179. Insulin-like.
IPR022350. Insulin-like_growth_factor.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
PfamiView protein in Pfam
PF08365. IGF2_C. 1 hit.
PF00049. Insulin. 1 hit.
PRINTSiPR02002. INSLNLIKEGF.
PR02006. INSLNLIKEGF2.
PR00276. INSULINFAMLY.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD005188. IGF2_C. 1 hit.
SMARTiView protein in SMART
SM00078. IlGF. 1 hit.
SUPFAMiSSF56994. SSF56994. 1 hit.
PROSITEiView protein in PROSITE
PS00262. INSULIN. 1 hit.

Sequencei

Sequence statusi: Complete.

E9QLW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGSVAGFQV PMGIPVGKSM LVLLISLAFA LCCIAAYGPG ETLCGGELVD
60 70 80 90 100
TLQFVCSDRG FYFSRPSSRA NRRSRGIVEE CCFRSCDLAL LETYCATPAK
110 120 130 140 150
SERDVSTSQA VLPDDFPRYP VGKFFQYDTW RQSAGRLRRG LPALLRARRG
160 170 180 190
RMLAKELKEF REAKRHRPLI VLPPKDPAHG GASSEMSSNH Q
Length:191
Mass (Da):21,061
Last modified:April 5, 2011 - v1
Checksum:iECF67B35396A7821
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013548 Genomic DNA. No translation available.
RefSeqiNP_034644.2. NM_010514.3.
UniGeneiMm.3862.

Genome annotation databases

EnsembliENSMUST00000121128; ENSMUSP00000114076; ENSMUSG00000048583.
GeneIDi16002.
UCSCiuc012fxo.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiE9QLW5_MOUSE
AccessioniPrimary (citable) accession number: E9QLW5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: August 30, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported