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Protein
Submitted name:

Insulin-like growth factor II

Gene

Igf2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Insulin-like growth factor IIImported
Gene namesi
Name:Igf2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:96434. Igf2.

Subcellular locationi

  • Secreted UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3535Sequence analysisAdd
BLAST
Chaini36 – 191156Sequence analysisPRO_5003243334Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

MaxQBiE9QLW5.
PaxDbiE9QLW5.

Expressioni

Gene expression databases

BgeeiE9QLW5.
ExpressionAtlasiE9QLW5. baseline and differential.
GenevisibleiE9QLW5. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000114076.

Structurei

3D structure databases

ProteinModelPortaliE9QLW5.
SMRiE9QLW5. Positions 41-99.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini41 – 9555IlGFInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the insulin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IY3P. Eukaryota.
ENOG4111KP2. LUCA.
GeneTreeiENSGT00530000063856.
OMAiFFQYDTW.

Family and domain databases

Gene3Di1.10.100.10. 1 hit.
InterProiIPR022334. IGF2.
IPR013576. IGF2_C.
IPR016179. Insulin-like.
IPR022350. Insulin-like_growth_factor.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
[Graphical view]
PfamiPF08365. IGF2_C. 1 hit.
PF00049. Insulin. 1 hit.
[Graphical view]
PRINTSiPR02002. INSLNLIKEGF.
PR02006. INSLNLIKEGF2.
PR00276. INSULINFAMLY.
ProDomiPD005188. IGF2_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 1 hit.
PROSITEiPS00262. INSULIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9QLW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGSVAGFQV PMGIPVGKSM LVLLISLAFA LCCIAAYGPG ETLCGGELVD
60 70 80 90 100
TLQFVCSDRG FYFSRPSSRA NRRSRGIVEE CCFRSCDLAL LETYCATPAK
110 120 130 140 150
SERDVSTSQA VLPDDFPRYP VGKFFQYDTW RQSAGRLRRG LPALLRARRG
160 170 180 190
RMLAKELKEF REAKRHRPLI VLPPKDPAHG GASSEMSSNH Q
Length:191
Mass (Da):21,061
Last modified:April 5, 2011 - v1
Checksum:iECF67B35396A7821
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013548 Genomic DNA. No translation available.
RefSeqiNP_034644.2. NM_010514.3.
UniGeneiMm.3862.

Genome annotation databases

EnsembliENSMUST00000121128; ENSMUSP00000114076; ENSMUSG00000048583.
GeneIDi16002.
UCSCiuc012fxo.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013548 Genomic DNA. No translation available.
RefSeqiNP_034644.2. NM_010514.3.
UniGeneiMm.3862.

3D structure databases

ProteinModelPortaliE9QLW5.
SMRiE9QLW5. Positions 41-99.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000114076.

Proteomic databases

MaxQBiE9QLW5.
PaxDbiE9QLW5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000121128; ENSMUSP00000114076; ENSMUSG00000048583.
GeneIDi16002.
UCSCiuc012fxo.1. mouse.

Organism-specific databases

CTDi3481.
MGIiMGI:96434. Igf2.

Phylogenomic databases

eggNOGiENOG410IY3P. Eukaryota.
ENOG4111KP2. LUCA.
GeneTreeiENSGT00530000063856.
OMAiFFQYDTW.

Miscellaneous databases

ChiTaRSiIgf2. mouse.
NextBioi288794.
SOURCEiSearch...

Gene expression databases

BgeeiE9QLW5.
ExpressionAtlasiE9QLW5. baseline and differential.
GenevisibleiE9QLW5. MM.

Family and domain databases

Gene3Di1.10.100.10. 1 hit.
InterProiIPR022334. IGF2.
IPR013576. IGF2_C.
IPR016179. Insulin-like.
IPR022350. Insulin-like_growth_factor.
IPR022353. Insulin_CS.
IPR022352. Insulin_family.
[Graphical view]
PfamiPF08365. IGF2_C. 1 hit.
PF00049. Insulin. 1 hit.
[Graphical view]
PRINTSiPR02002. INSLNLIKEGF.
PR02006. INSLNLIKEGF2.
PR00276. INSULINFAMLY.
ProDomiPD005188. IGF2_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00078. IlGF. 1 hit.
[Graphical view]
SUPFAMiSSF56994. SSF56994. 1 hit.
PROSITEiPS00262. INSULIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9QLW5_MOUSE
AccessioniPrimary (citable) accession number: E9QLW5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 11, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.