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Protein
Submitted name:

Potassium voltage-gated channel subfamily C member 2

Gene

Kcnc2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Potassium channelSAAS annotation, Voltage-gated channelSAAS annotation

Keywords - Biological processi

Ion transport, Potassium transport, Transport

Keywords - Ligandi

Potassium

Enzyme and pathway databases

ReactomeiREACT_287159. Voltage gated Potassium channels.
REACT_297430. Glucagon-like Peptide-1 (GLP1) regulates insulin secretion.

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium voltage-gated channel subfamily C member 2Imported
Gene namesi
Name:Kcnc2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:96668. Kcnc2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiE9QLW0.
GenevisibleiE9QLW0. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000089814.

Structurei

3D structure databases

ProteinModelPortaliE9QLW0.
SMRiE9QLW0. Positions 6-484.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118846.
KOiK04888.
OMAiRKDNCKE.
OrthoDBiEOG7CRTPP.
TreeFamiTF352511.

Family and domain databases

Gene3Di1.20.120.350. 1 hit.
InterProiIPR000210. BTB/POZ-like.
IPR011333. BTB/POZ_fold.
IPR027359. Channel_four-helix_dom.
IPR005821. Ion_trans_dom.
IPR003091. K_chnl.
IPR003968. K_chnl_volt-dep_Kv.
IPR003974. K_chnl_volt-dep_Kv3.
IPR003131. T1-type_BTB.
IPR028325. VG_K_chnl.
[Graphical view]
PANTHERiPTHR11537. PTHR11537. 1 hit.
PfamiPF02214. BTB_2. 2 hits.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR00169. KCHANNEL.
PR01491. KVCHANNEL.
PR01498. SHAWCHANNEL.
SMARTiSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 2 hits.

Sequencei

Sequence statusi: Complete.

E9QLW0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKIESNERV ILNVGGTRHE TYRSTLKTLP GTRLALLASS EPQGDCLTAA
60 70 80 90 100
GDKLQPLPPP LSPPPRPPPL SPVPSGCFEG GAGNCSSHGG NGGNGGSDHP
110 120 130 140 150
GGGREFFFDR HPGVFAYVLN YYRTGKLHCP ADVCGPLFEE ELAFWGIDET
160 170 180 190 200
DVEPCCWMTY RQHRDAEEAL DIFETPDLIG GDPGDDEDLA AKRLGIEDAA
210 220 230 240 250
GLGGPDGKSG RWRKLQPRMW ALFEDPYSSR AARFIAFASL FFILVSITTF
260 270 280 290 300
CLETHEAFNI VKNKTEPVIN GTSPVLQYEI ETDPALTYVE GVCVVWFTFE
310 320 330 340 350
FLVRIVFSPN KLEFIKNLLN IIDFVAILPF YLEVGLSGLS SKAAKDVLGF
360 370 380 390 400
LRVVRFVRIL RIFKLTRHFV GLRVLGHTLR ASTNEFLLLI IFLALGVLIF
410 420 430 440 450
ATMIYYAERV GAQPNDPSAS EHTQFKNIPI GFWWAVVTMT TLGYGDMYPQ
460 470 480 490 500
TWSGMLVGAL CALAGVLTIA MPVPVIVNNF GMYYSLAMAK QKLPRKRKKH
510 520 530 540 550
IPPAPLASSP TFCKTELNMA CNSTQSDTCL GKENRLLEHN RSVLSGDDST
560 570 580 590 600
GSEPPLSPPE RLPIRRSSTR DKNRRGETCF LLTTGDYTCA SDGGIRKAST
610 620 630
LEPMESTAQT KGDTRPEAHW NCAHLLNFGC PTGSSFPTL
Length:639
Mass (Da):70,183
Last modified:April 5, 2011 - v1
Checksum:i15CB8C3DD2E6C6D8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121610 Genomic DNA. No translation available.
AC153500 Genomic DNA. No translation available.
RefSeqiNP_001020752.1. NM_001025581.1.
XP_011241757.1. XM_011243455.1.
UniGeneiMm.336242.

Genome annotation databases

EnsembliENSMUST00000092175; ENSMUSP00000089814; ENSMUSG00000035681.
GeneIDi268345.
KEGGimmu:268345.
UCSCiuc007hap.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121610 Genomic DNA. No translation available.
AC153500 Genomic DNA. No translation available.
RefSeqiNP_001020752.1. NM_001025581.1.
XP_011241757.1. XM_011243455.1.
UniGeneiMm.336242.

3D structure databases

ProteinModelPortaliE9QLW0.
SMRiE9QLW0. Positions 6-484.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000089814.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000092175; ENSMUSP00000089814; ENSMUSG00000035681.
GeneIDi268345.
KEGGimmu:268345.
UCSCiuc007hap.1. mouse.

Organism-specific databases

CTDi3747.
MGIiMGI:96668. Kcnc2.

Phylogenomic databases

GeneTreeiENSGT00760000118846.
KOiK04888.
OMAiRKDNCKE.
OrthoDBiEOG7CRTPP.
TreeFamiTF352511.

Enzyme and pathway databases

ReactomeiREACT_287159. Voltage gated Potassium channels.
REACT_297430. Glucagon-like Peptide-1 (GLP1) regulates insulin secretion.

Miscellaneous databases

ChiTaRSiKcnc2. mouse.
NextBioi392247.
SOURCEiSearch...

Gene expression databases

BgeeiE9QLW0.
GenevisibleiE9QLW0. MM.

Family and domain databases

Gene3Di1.20.120.350. 1 hit.
InterProiIPR000210. BTB/POZ-like.
IPR011333. BTB/POZ_fold.
IPR027359. Channel_four-helix_dom.
IPR005821. Ion_trans_dom.
IPR003091. K_chnl.
IPR003968. K_chnl_volt-dep_Kv.
IPR003974. K_chnl_volt-dep_Kv3.
IPR003131. T1-type_BTB.
IPR028325. VG_K_chnl.
[Graphical view]
PANTHERiPTHR11537. PTHR11537. 1 hit.
PfamiPF02214. BTB_2. 2 hits.
PF00520. Ion_trans. 1 hit.
[Graphical view]
PRINTSiPR00169. KCHANNEL.
PR01491. KVCHANNEL.
PR01498. SHAWCHANNEL.
SMARTiSM00225. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF54695. SSF54695. 2 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9QLW0_MOUSE
AccessioniPrimary (citable) accession number: E9QLW0
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 22, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.