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Protein
Submitted name:

Rab3 GTPase-activating protein non-catalytic subunit

Gene

Rab3gap2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-6811436 COPI-independent Golgi-to-ER retrograde traffic
R-MMU-8876198 RAB GEFs exchange GTP for GDP on RABs

Names & Taxonomyi

Protein namesi
Submitted name:
Rab3 GTPase-activating protein non-catalytic subunitImported
Gene namesi
Name:Rab3gap2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1916043 Rab3gap2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiE9QKE4
PeptideAtlasiE9QKE4
PRIDEiE9QKE4

Expressioni

Gene expression databases

BgeeiENSMUSG00000039318
ExpressionAtlasiE9QKE4 baseline and differential
GenevisibleiE9QKE4 MM

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini73 – 497RAB3GAP2_NInterPro annotationAdd BLAST425
Domaini767 – 1365RAB3GAP2_CInterPro annotationAdd BLAST599

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili671 – 698Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2727 Eukaryota
ENOG410XTJ2 LUCA
GeneTreeiENSGT00390000005794
KOiK19937
OMAiWWQQMRT
OrthoDBiEOG091G00YC
TreeFamiTF314817

Family and domain databases

InterProiView protein in InterPro
IPR026059 Rab3-gap_reg
IPR029257 RAB3GAP2_C
IPR032839 RAB3GAP_N
PANTHERiPTHR12472 PTHR12472, 1 hit
PfamiView protein in Pfam
PF14656 RAB3GAP2_C, 1 hit
PF14655 RAB3GAP2_N, 1 hit

Sequencei

Sequence statusi: Complete.

E9QKE4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MACSIVQFCS FQDLQSARDF LFPHLREETP GALKRDPSKT SSWEDDSWGA
60 70 80 90 100
WEETEPREPE EEGNTSKTQK NSWLQECVLS LSPTSDLMVI AREQKAAFLV
110 120 130 140 150
PKWKHGDKGK EEMQFAVGWS GSVSAEEGEY VTSALCIPLA SQKRSSTGRP
160 170 180 190 200
DWTCIVVGFT SGYVRFYTES GVLLLAQLLN EDKVLQLKCR TYEIPRHPGV
210 220 230 240 250
TEQNEELSIL YPAAIVTIDG FSLFQSLRAC RNQVAKAAAS GNENIQPPPL
260 270 280 290 300
AYKKWGLQDI DTIIDHASIG IMTLSPFDQM KTASNIGGFN AAIKNSPPAM
310 320 330 340 350
SQYITVGSSP FTGFFYALEG STQPLLSHVA LAVASKLTSA LFSAASGWLG
360 370 380 390 400
WKSKHEEDTV QKQKPKMEPA TPLAVRFGLP DSRRHGESIC LSPCNTLAAV
410 420 430 440 450
TDDFGRVILL DVARGIAIRM WKGYRDAQVG WIQIVEDLHE RVPEKGGFSP
460 470 480 490 500
FGNTQGPSRV AQFLVIYAPR RGILEVWNTQ QGPRVGAFNV GKHCRLLYPG
510 520 530 540 550
YKIMGLNNVT SQSWQPQTYQ ICLVDPVSAS VKAVNVPFHL ALSDKKSERA
560 570 580 590 600
KDLHLVKKLS ALLRAKSPRP DSFETEIKEL ILDIKYPATK KQALESILAS
610 620 630 640 650
DRLSFSCLRN VTQTLMDTLK NQELESVDEG LLQFCASKLK LLHLYESVSQ
660 670 680 690 700
LNTLDFHSDT PFSDNDLAVL LRLDDKELLK LRALLEKYKQ ENTKATVRFS
710 720 730 740 750
EDADRVLPVK TFLEYLEYEK DALSIRKVGE EECVALGSFF FWKCLHGESS
760 770 780 790 800
TEEMCHSLES AGLSPQQLLS LLLSVWLSKE KDILDKPQSV CCLHTMLSLL
810 820 830 840 850
SKMKVAIDET WDSQSVSPWW QQMRMACIQS ENSGAALLSA HVGHSVAAQM
860 870 880 890 900
SSGATDKKFS QMVLDADAEA LTDSWEALSL DTEYWKLLLR QLEDCLILQT
910 920 930 940 950
LLHSKLSPPA AKAPSLQSEP LPRLSVKKLL EGGKGGIADS VAKWIFKQDL
960 970 980 990 1000
SPELLKCANK ERDVENPDEP REGITRSFPE VSEVEIDLGA VPDLLHLAYE
1010 1020 1030 1040 1050
QFPCSLELDV LHAHCCWEYV VQWNKDPEEA RFLVRSIEHL KHILNPHVQN
1060 1070 1080 1090 1100
GIALMMWNTF LVKRFSAATY LMDKVGKSPK DRLCRRDVGM SDTALTSFLG
1110 1120 1130 1140 1150
SCLELLQTSL EADISRDEVQ VPVLDTEDAW LSVEGPISIV ELALEQKPIH
1160 1170 1180 1190 1200
YPLVEHHSVL CSILYASMRF SLKSVKPLAL FDSKGKNAFF KDLTSIQLLP
1210 1220 1230 1240 1250
SGEMDPNFIS VRQQFLLKVV SAAVQAQHSK DKDPSAEAAN THWKDLNWPG
1260 1270 1280 1290 1300
LAVDLAHHLQ VSDDVIRRHY VGELYSHGAD LLGEEAIFQV QDKEVLASQL
1310 1320 1330 1340 1350
LVLTGQRLAH ALFHTQTKEG MELLARLPPT LCTWLKAMNP QDLQNTGVPI
1360 1370 1380
AATAKLVHKV MELLPEKHGQ YSLALHLIDA VEAMATL
Length:1,387
Mass (Da):154,640
Last modified:April 5, 2011 - v1
Checksum:i7BD56871F97D0C5D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC129195 Genomic DNA No translation available.
AC131084 Genomic DNA No translation available.
AC158963 Genomic DNA No translation available.
RefSeqiNP_001157226.1, NM_001163754.1
UniGeneiMm.275841

Genome annotation databases

EnsembliENSMUST00000069652; ENSMUSP00000066325; ENSMUSG00000039318
GeneIDi98732
KEGGimmu:98732
UCSCiuc007dyu.2 mouse

Similar proteinsi

Entry informationi

Entry nameiE9QKE4_MOUSE
AccessioniPrimary (citable) accession number: E9QKE4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 25, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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