Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Protein Adgre5

Gene

Adgre5

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-373080. Class B/2 (Secretin family receptors).
R-MMU-6798695. Neutrophil degranulation.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Adgre5Imported
Gene namesi
Name:Adgre5Imported
Synonyms:Cd97Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:1347095. Adgre5.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei535 – 554HelicalSequence analysisAdd BLAST20
Transmembranei566 – 583HelicalSequence analysisAdd BLAST18
Transmembranei595 – 627HelicalSequence analysisAdd BLAST33
Transmembranei639 – 656HelicalSequence analysisAdd BLAST18
Transmembranei676 – 700HelicalSequence analysisAdd BLAST25
Transmembranei721 – 744HelicalSequence analysisAdd BLAST24
Transmembranei750 – 773HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_500324638829 – 818Sequence analysisAdd BLAST790

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

MaxQBiE9QJS7.
PaxDbiE9QJS7.
PeptideAtlasiE9QJS7.
PRIDEiE9QJS7.

Expressioni

Gene expression databases

BgeeiENSMUSG00000002885.
ExpressionAtlasiE9QJS7. baseline and differential.
GenevisibleiE9QJS7. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000075240.

Structurei

3D structure databases

ProteinModelPortaliE9QJS7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini69 – 107EGF-likeInterPro annotationAdd BLAST39
Domaini165 – 203EGF-likeInterPro annotationAdd BLAST39
Domaini214 – 252EGF-likeInterPro annotationAdd BLAST39
Domaini479 – 524GPSInterPro annotationAdd BLAST46
Domaini529 – 774G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST246

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

EGF-like domainSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG4193. Eukaryota.
ENOG410XSD2. LUCA.
GeneTreeiENSGT00830000128227.
OMAiYRKWACL.
OrthoDBiEOG091G063N.
TreeFamiTF316380.

Family and domain databases

InterProiIPR001881. EGF-like_Ca-bd_dom.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR017981. GPCR_2-like.
IPR003056. GPCR_2_CD97.
IPR000832. GPCR_2_secretin-like.
IPR000203. GPS.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF07645. EGF_CA. 3 hits.
PF01825. GPS. 1 hit.
[Graphical view]
PRINTSiPR01278. CD97PROTEIN.
PR00249. GPCRSECRETIN.
SMARTiSM00181. EGF. 4 hits.
SM00179. EGF_CA. 3 hits.
SM00303. GPS. 1 hit.
[Graphical view]
PROSITEiPS00010. ASX_HYDROXYL. 3 hits.
PS50026. EGF_3. 3 hits.
PS01187. EGF_CA. 3 hits.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9QJS7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGVRCPGLL VVCILLSLSG AGTQKAESKN CAKWCPINSK CVSNRSCVCK
60 70 80 90 100
PGFSSEKELI TNPAESCEDI NECLLPGFSC GDFAMCKNSE GSYTCVCNLG
110 120 130 140 150
YKLLSGAESF VNESENTCQA SVNTGMTPVP SRIHTVTTAP GNLPEQTTTV
160 170 180 190 200
HQTQMGDSEE RTPKDVNECI SGQNHCHQST HCINKLGGYS CICRQGWKPV
210 220 230 240 250
PGSPNGPVST VCEDVDECSS GQHQCHNSTV CKNTVGSYKC HCRPGWKPTS
260 270 280 290 300
GSLRGPDTIC QEPPFPTWTL LPTAHSQTLL RFSVEVQNLL RDFNPATVNY
310 320 330 340 350
TIQKLIEAVD KLLEDPMETE TQQVAAQLLS NLEQSLRTLA QFLPKGPFTY
360 370 380 390 400
TSPSNTELSL MVKEQDNKDV TTVHHGQTWM ELDWAVTAGA KISENGSSVA
410 420 430 440 450
GILSSPNMEK LLGNTPLNLE QRRASLEDFY GSPIPSVSLK LLSNINSVFL
460 470 480 490 500
TNTNTEKLAS NVTFKFDFTS VESIEPRHEL ICAFWKAHNG NGYWDTDGCS
510 520 530 540 550
MNGTGFCHCN HLTSFAILMA QYHVQDPRLE LITKVGLLLS LICLLLCILT
560 570 580 590 600
FLLVKPIQSS RTMVHLHLCI CLFLGSIIFL VGVENEGGEV GLRCRLVAVM
610 620 630 640 650
LHFCFLAAFC WMALEGVELY FLVVRVFQGQ GLSTWQRCLI GYGVPLLIVA
660 670 680 690 700
ISMAVVKMDG YGHATYCWLD FRKQGFLWSF SGPVAFIIFC NAAIFVITVW
710 720 730 740 750
KLTKKFSEIN PNMKKLRKAR VLTITSIAQL LVLGCTWGFG LFLFNPHSTW
760 770 780 790 800
LSYIFTLLNC LQGLFLYVML CLLNKKVREE YWKWACMVTG SKYTEFNSST
810
TGTGTSQTRA LRSSESGM
Length:818
Mass (Da):90,428
Last modified:April 5, 2011 - v1
Checksum:i2EC6B2BAB267A589
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC164432 Genomic DNA. No translation available.
RefSeqiNP_036055.2. NM_011925.2.
UniGeneiMm.334648.

Genome annotation databases

EnsembliENSMUST00000075843; ENSMUSP00000075240; ENSMUSG00000002885.
GeneIDi26364.
UCSCiuc009mlc.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC164432 Genomic DNA. No translation available.
RefSeqiNP_036055.2. NM_011925.2.
UniGeneiMm.334648.

3D structure databases

ProteinModelPortaliE9QJS7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000075240.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

MaxQBiE9QJS7.
PaxDbiE9QJS7.
PeptideAtlasiE9QJS7.
PRIDEiE9QJS7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000075843; ENSMUSP00000075240; ENSMUSG00000002885.
GeneIDi26364.
UCSCiuc009mlc.2. mouse.

Organism-specific databases

CTDi976.
MGIiMGI:1347095. Adgre5.

Phylogenomic databases

eggNOGiKOG4193. Eukaryota.
ENOG410XSD2. LUCA.
GeneTreeiENSGT00830000128227.
OMAiYRKWACL.
OrthoDBiEOG091G063N.
TreeFamiTF316380.

Enzyme and pathway databases

ReactomeiR-MMU-373080. Class B/2 (Secretin family receptors).
R-MMU-6798695. Neutrophil degranulation.

Miscellaneous databases

ChiTaRSiCd97. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000002885.
ExpressionAtlasiE9QJS7. baseline and differential.
GenevisibleiE9QJS7. MM.

Family and domain databases

InterProiIPR001881. EGF-like_Ca-bd_dom.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR017981. GPCR_2-like.
IPR003056. GPCR_2_CD97.
IPR000832. GPCR_2_secretin-like.
IPR000203. GPS.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF07645. EGF_CA. 3 hits.
PF01825. GPS. 1 hit.
[Graphical view]
PRINTSiPR01278. CD97PROTEIN.
PR00249. GPCRSECRETIN.
SMARTiSM00181. EGF. 4 hits.
SM00179. EGF_CA. 3 hits.
SM00303. GPS. 1 hit.
[Graphical view]
PROSITEiPS00010. ASX_HYDROXYL. 3 hits.
PS50026. EGF_3. 3 hits.
PS01187. EGF_CA. 3 hits.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
PS50221. GPS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE9QJS7_MOUSE
AccessioniPrimary (citable) accession number: E9QJS7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 30, 2016
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.