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Protein
Submitted name:

Uncharacterized protein

Gene

tgm1l1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Cofactori

Note: Binds 1 calcium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei369 – 3691UniRule annotation
Active sitei428 – 4281UniRule annotation
Active sitei451 – 4511UniRule annotation
Metal bindingi491 – 4911CalciumUniRule annotation
Metal bindingi493 – 4931CalciumUniRule annotation
Metal bindingi540 – 5401CalciumUniRule annotation
Metal bindingi545 – 5451CalciumUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

GO - Biological processi

  1. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:tgm1l1Imported
Synonyms:si:ch211-9d9.3Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Chromosome 2

Organism-specific databases

ZFINiZDB-GENE-060503-139. tgm1l1.

Expressioni

Gene expression databases

BgeeiE9QB19.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119108.
KOiK05619.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9QB19-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPGERQSIRD NSAVGRFHGV SARNGEAVAE KPSESKTKKP ESGCRRWLRK
60 70 80 90 100
ACPCCLRRQS NSYDLTSEAD GVVAGNEEIE QPASPVSVSV ETNVDDLSLV
110 120 130 140 150
VRSVDLLSRK TDRNKKEHHT DQYSGDQLII RRGQTFQIEL ELSRPFNPNT
160 170 180 190 200
DKLHLELKTG ALPLVSKGTH IIIPLVEELQ DERWEAKIVE QNLNRAKLSI
210 220 230 240 250
NSSVNAVIGK YTLTVVTQCL KTNESTTHDP EKDIYMLFNP WCEDDAVFME
260 270 280 290 300
GERELNEYVL NDTGRIYYGT EKQIGARTWN FGQFDEGILE ACLFVLDNSE
310 320 330 340 350
VPPSGRGDPV NVVRVISAMI NSPDDRGVLE GNWSGNYTGG TSPTAWSGSV
360 370 380 390 400
EILKQYHREG GTPVKYGQCW VFSGVTTTVL RCLGIPARSV TNFQSAHDTD
410 420 430 440 450
VSLTTDVYFD EDMEPIHHLN SDSVWNFHVW NDCWLARPDL PPGFGGWQAV
460 470 480 490 500
DSTPQETSHG TFRCGPASLA AVRSGQVYLK YDVPFVFAEV NSDKIYWQRN
510 520 530 540 550
LDGTFSQIHS EKKAVGHCIS TKAVGSDERV DITDVYKYPE GSEEERIAVE
560 570 580 590 600
TACRYGSKPD VYSSAMAEDV QVEVRMEGEG PRMGGDAQLK IVVKNMSSQP
610 620 630 640 650
RRTTLHSQAA VMYYTGVLKD TVKKDKLSVE LMPQEEKVIE WTLPYTQYQN
660 670 680 690 700
QLVDQAALML TLSGRVSETQ QVLANQTSFR LRTPDLQIEP IGEAYVGKEA
710 720 730 740 750
SAKISFTNPL PCTLRNVVVR VEGLGLRDLH PIKVGDVGKH GKVMVTEHFI
760 770 780
PSIAGERKLV ASLDCKQLTQ VHGVADIIVH ESQ
Length:783
Mass (Da):87,201
Last modified:April 5, 2011 - v1
Checksum:i5F5CBD2C291BC3C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL929335 Genomic DNA. No translation available.
RefSeqiXP_694950.3. XM_689858.6.
UniGeneiDr.155825.
Dr.78708.

Genome annotation databases

EnsembliENSDART00000027444; ENSDARP00000012174; ENSDARG00000012130.
GeneIDi566581.
KEGGidre:566581.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL929335 Genomic DNA. No translation available.
RefSeqiXP_694950.3. XM_689858.6.
UniGeneiDr.155825.
Dr.78708.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000027444; ENSDARP00000012174; ENSDARG00000012130.
GeneIDi566581.
KEGGidre:566581.

Organism-specific databases

CTDi566581.
ZFINiZDB-GENE-060503-139. tgm1l1.

Phylogenomic databases

GeneTreeiENSGT00760000119108.
KOiK05619.

Miscellaneous databases

NextBioi20888264.

Gene expression databases

BgeeiE9QB19.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR013808. Transglutaminase_CS.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEiPS00547. TRANSGLUTAMINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  2. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.

Entry informationi

Entry nameiE9QB19_DANRE
AccessioniPrimary (citable) accession number: E9QB19
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: February 4, 2015
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.