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Protein
Submitted name:

Protein Inpp5a

Gene

Inpp5a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. inositol-polyphosphate 5-phosphatase activity Source: MGI
  2. PH domain binding Source: MGI

GO - Biological processi

  1. inositol phosphate dephosphorylation Source: MGI
  2. phosphatidylinositol dephosphorylation Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_293546. Synthesis of IP2, IP, and Ins in the cytosol.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Inpp5aImported
Gene namesi
Name:Inpp5aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:2686961. Inpp5a.

Subcellular locationi

GO - Cellular componenti

  1. extracellular vesicular exosome Source: MGI
  2. membrane Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiE9QAS7.
PRIDEiE9QAS7.

Expressioni

Gene expression databases

BgeeiE9QAS7.
ExpressionAtlasiE9QAS7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9QAS7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000015226.
InParanoidiE9QAS7.
KOiK01106.
OMAiQGRQYMN.
PhylomeDBiE9QAS7.
TreeFamiTF314246.

Family and domain databases

Gene3Di3.60.10.10. 1 hit.
InterProiIPR005135. Endo/exonuclease/phosphatase.
IPR000300. IPPc.
[Graphical view]
PfamiPF03372. Exo_endo_phos. 1 hit.
[Graphical view]
SMARTiSM00128. IPPc. 1 hit.
[Graphical view]
SUPFAMiSSF56219. SSF56219. 3 hits.

Sequencei

Sequence statusi: Complete.

E9QAS7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGKAAAPGT AVLLVTANVG SLFDDPENLQ KNWLREFYQV LHTHKPHFMA
60 70 80 90 100
LHCQEFGGKN YEASMSHVDK FVKELLSSDA MKEYNRARVY LDENYKSQEH
110 120 130 140 150
FTALGSFYFL HESLKNIYQF DFKAKKYKKV TGKEIYSDTL ESTPMLEKEK
160 170 180 190 200
FPQDYFPECK WSRKGFIRTR WCIADCAFDL VNIHLFHDAS NLVAWETSPS
210 220 230 240 250
VYSGVRHKAL GYVLDRIIDQ RFEKVSYFVF GDFNFRLDSK SVVETLCTKA
260 270 280 290 300
TMQTVRAADT NEVVKLIFRE SDNDRKVVLQ LEKKLFDYFN QDVFRDNNGT
310 320 330 340 350
ALLEFDKELS VFKDRLYELD ISFPPSYPYS EDSSQGEQYM NTRCPAWCDR
360 370 380 390 400
ILMSLSAKEL VLKSESEEKV ATYDHIGPNV CMGDHKPVFL AFRIAPGAGK
410 420
RCQRRERILE RPPCSSVSNS SS
Length:422
Mass (Da):48,812
Last modified:April 5, 2011 - v1
Checksum:i2B9BA725D3A2AA8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC112670 Genomic DNA. No translation available.
AC118735 Genomic DNA. No translation available.
RefSeqiNP_898967.2. NM_183144.3.
UniGeneiMm.28308.

Genome annotation databases

EnsembliENSMUST00000026550; ENSMUSP00000026550; ENSMUSG00000025477.
GeneIDi212111.
KEGGimmu:212111.
UCSCiuc009kfq.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC112670 Genomic DNA. No translation available.
AC118735 Genomic DNA. No translation available.
RefSeqiNP_898967.2. NM_183144.3.
UniGeneiMm.28308.

3D structure databases

ProteinModelPortaliE9QAS7.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiE9QAS7.
PRIDEiE9QAS7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000026550; ENSMUSP00000026550; ENSMUSG00000025477.
GeneIDi212111.
KEGGimmu:212111.
UCSCiuc009kfq.2. mouse.

Organism-specific databases

CTDi3632.
MGIiMGI:2686961. Inpp5a.

Phylogenomic databases

GeneTreeiENSGT00390000015226.
InParanoidiE9QAS7.
KOiK01106.
OMAiQGRQYMN.
PhylomeDBiE9QAS7.
TreeFamiTF314246.

Enzyme and pathway databases

ReactomeiREACT_293546. Synthesis of IP2, IP, and Ins in the cytosol.

Miscellaneous databases

ChiTaRSiInpp5a. mouse.
NextBioi373454.
PROiE9QAS7.
SOURCEiSearch...

Gene expression databases

BgeeiE9QAS7.
ExpressionAtlasiE9QAS7. baseline and differential.

Family and domain databases

Gene3Di3.60.10.10. 1 hit.
InterProiIPR005135. Endo/exonuclease/phosphatase.
IPR000300. IPPc.
[Graphical view]
PfamiPF03372. Exo_endo_phos. 1 hit.
[Graphical view]
SMARTiSM00128. IPPc. 1 hit.
[Graphical view]
SUPFAMiSSF56219. SSF56219. 3 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9QAS7_MOUSE
AccessioniPrimary (citable) accession number: E9QAS7
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 1, 2015
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.