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E9QAQ5 (E9QAQ5_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length433 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000110398

Ontologies

Keywords
   LigandATP-binding RuleBase RU000304
Nucleotide-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processER overload response

Inferred from direct assay PubMed 14744935. Source: MGI

Wnt signaling pathway

Inferred from genetic interaction PubMed 16815997PubMed 23074275. Source: MGI

axonogenesis

Inferred from genetic interaction PubMed 18716223. Source: MGI

canonical Wnt signaling pathway

Inferred from direct assay PubMed 15282335. Source: MGI

cell migration

Inferred from genetic interaction PubMed 17986005. Source: MGI

cell proliferation

Traceable author statement PubMed 10894547. Source: MGI

fat cell differentiation

Inferred from direct assay PubMed 12502791. Source: MGI

intracellular signal transduction

Inferred from sequence orthology PubMed 14749367. Source: MGI

myoblast fusion

Inferred from direct assay PubMed 15282335. Source: MGI

myotube differentiation

Inferred from genetic interaction PubMed 15282335. Source: MGI

negative regulation of apoptotic process

Inferred from mutant phenotype PubMed 10894547. Source: MGI

negative regulation of cardiac muscle hypertrophy

Inferred from direct assay PubMed 11782539. Source: MGI

organ morphogenesis

Inferred from mutant phenotype PubMed 10894547. Source: MGI

peptidyl-serine phosphorylation

Inferred from direct assay PubMed 17986005. Source: MGI

positive regulation of peptidyl-serine phosphorylation

Inferred from direct assay PubMed 17986005. Source: MGI

positive regulation of peptidyl-threonine phosphorylation

Inferred from direct assay PubMed 17986005. Source: MGI

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

Inferred from genetic interaction PubMed 22660580. Source: MGI

positive regulation of protein binding

Inferred from direct assay PubMed 19141611. Source: MGI

positive regulation of stem cell differentiation

Inferred from mutant phenotype PubMed 22064483. Source: MGI

protein export from nucleus

Inferred from direct assay PubMed 11782539. Source: MGI

protein localization to microtubule

Inferred from genetic interaction PubMed 18716223. Source: MGI

protein phosphorylation

Inferred from direct assay PubMed 12432063PubMed 12805290PubMed 14730361PubMed 17026964. Source: MGI

re-entry into mitotic cell cycle

Inferred from direct assay PubMed 12502791. Source: MGI

   Cellular_componentbeta-catenin destruction complex

Inferred from direct assay PubMed 10318824. Source: MGI

cytosol

Inferred from direct assay PubMed 12502791. Source: MGI

dendritic shaft

Inferred from direct assay PubMed 12805290. Source: MGI

growth cone

Inferred from direct assay PubMed 12805290. Source: MGI

membrane-bounded organelle

Inferred from direct assay PubMed 12805290. Source: MGI

neuronal cell body

Inferred from direct assay PubMed 12805290. Source: MGI

nucleus

Inferred from direct assay PubMed 12502791PubMed 22064483. Source: MGI

ribonucleoprotein complex

Inferred from direct assay PubMed 21709260. Source: MGI

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

beta-catenin binding

Inferred from physical interaction PubMed 12874278. Source: MGI

protein binding

Inferred from physical interaction PubMed 12432063PubMed 12805290PubMed 16510873PubMed 18632848PubMed 19047045PubMed 21471969PubMed 22064483PubMed 9554852. Source: MGI

protein kinase activity

Inferred from direct assay PubMed 14730361. Source: MGI

protein serine/threonine kinase activity

Inferred from direct assay PubMed 12805290PubMed 17986005PubMed 22660580. Source: MGI

tau-protein kinase activity

Inferred from direct assay PubMed 15192701. Source: MGI

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
E9QAQ5 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: 901D4D23D958F2D4

FASTA43347,990
        10         20         30         40         50         60 
MSGRPRTTSF AESCKPVQQP SAFGSMKVSR DKDGSKVTTV VATPGQGPDR PQEVSYTDTK 

        70         80         90        100        110        120 
VIGNGSFGVV YQAKLCDSGE LVAIKKVLQD KRFKNRELQI MRKLDHCNIV RLRYFFYSSG 

       130        140        150        160        170        180 
EKKDEVYLNL VLDYVPETVY RVARHYSRAK QTLPVIYVKL YMYQLFRSLA YIHSFGICHR 

       190        200        210        220        230        240 
DIKPQNLLLD PDTAVLKLCD FGSAKQLVRG EPNVSYICSR YYRAPELIFG ATDYTSSIDV 

       250        260        270        280        290        300 
WSAGCVLAEL LLGQPIFPGD SGVDQLVEII KVLGTPTREQ IREMNPNYTE FKFPQIKAHP 

       310        320        330        340        350        360 
WTKDSPGAGH FTPGVRVFRP RTPPEAIALC SRLLEYTPTA RLTPLEACAH SFFDELRDPN 

       370        380        390        400        410        420 
VKLPNGRDTP ALFNFTTQEL SSNPPLATIL IPPHARIQAA ASPPANATAA SDTNAGDRGQ 

       430 
TNNAASASAS NST 

« Hide

References

« Hide 'large scale' references
[1]"Phosphoproteomic analysis of the developing mouse brain."
Ballif B.A., Villen J., Beausoleil S.A., Schwartz D., Gygi S.P.
Mol. Cell. Proteomics 3:1093-1101(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[2]"Large-scale phosphorylation analysis of mouse liver."
Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[3]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000110398.
[4]Ensembl
Submitted (MAY-2011) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000110398.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC120020 Genomic DNA. No translation available.
AC154284 Genomic DNA. No translation available.
RefSeqXP_006522488.1. XM_006522425.1.
UniGeneMm.394930.

3D structure databases

ProteinModelPortalE9QAQ5.
SMRE9QAQ5. Positions 6-399.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEE9QAQ5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000114750; ENSMUSP00000110398; ENSMUSG00000022812.
GeneID56637.
KEGGmmu:56637.

Organism-specific databases

CTD2932.
MGIMGI:1861437. Gsk3b.

Phylogenomic databases

GeneTreeENSGT00520000055635.
KOK03083.
OMANAGERVQ.

Gene expression databases

ArrayExpressE9QAQ5.
BgeeE9QAQ5.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSGSK3B. mouse.
NextBio35555931.
SOURCESearch...

Entry information

Entry nameE9QAQ5_MOUSE
AccessionPrimary (citable) accession number: E9QAQ5
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 11, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)