Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Glycogen synthase kinase-3 beta

Gene

Gsk3b

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotation, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Glycogen synthase kinase-3 betaImported
Gene namesi
Name:Gsk3bImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:1861437 Gsk3b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiE9QAQ5
PeptideAtlasiE9QAQ5
PRIDEiE9QAQ5

Expressioni

Gene expression databases

BgeeiENSMUSG00000022812
ExpressionAtlasiE9QAQ5 baseline and differential

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiE9QAQ5, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliE9QAQ5
SMRiE9QAQ5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 353Protein kinaseInterPro annotationAdd BLAST298

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0658 Eukaryota
COG0515 LUCA
GeneTreeiENSGT00520000055635
KOiK03083
OMAiYSNGDKK
OrthoDBiEOG091G099S

Family and domain databases

InterProiView protein in InterPro
IPR033573 GSK3B
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PANTHERiPTHR24057:SF8 PTHR24057:SF8, 1 hit
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

E9QAQ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGRPRTTSF AESCKPVQQP SAFGSMKVSR DKDGSKVTTV VATPGQGPDR
60 70 80 90 100
PQEVSYTDTK VIGNGSFGVV YQAKLCDSGE LVAIKKVLQD KRFKNRELQI
110 120 130 140 150
MRKLDHCNIV RLRYFFYSSG EKKDEVYLNL VLDYVPETVY RVARHYSRAK
160 170 180 190 200
QTLPVIYVKL YMYQLFRSLA YIHSFGICHR DIKPQNLLLD PDTAVLKLCD
210 220 230 240 250
FGSAKQLVRG EPNVSYICSR YYRAPELIFG ATDYTSSIDV WSAGCVLAEL
260 270 280 290 300
LLGQPIFPGD SGVDQLVEII KVLGTPTREQ IREMNPNYTE FKFPQIKAHP
310 320 330 340 350
WTKDSPGAGH FTPGVRVFRP RTPPEAIALC SRLLEYTPTA RLTPLEACAH
360 370 380 390 400
SFFDELRDPN VKLPNGRDTP ALFNFTTQEL SSNPPLATIL IPPHARIQAA
410 420 430
ASPPANATAA SDTNAGDRGQ TNNAASASAS NST
Length:433
Mass (Da):47,990
Last modified:April 5, 2011 - v1
Checksum:i901D4D23D958F2D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120020 Genomic DNA No translation available.
AC154284 Genomic DNA No translation available.
RefSeqiNP_001334161.1, NM_001347232.1
UniGeneiMm.394930

Genome annotation databases

EnsembliENSMUST00000114750; ENSMUSP00000110398; ENSMUSG00000022812
GeneIDi56637
KEGGimmu:56637

Similar proteinsi

Entry informationi

Entry nameiE9QAQ5_MOUSE
AccessioniPrimary (citable) accession number: E9QAQ5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: March 28, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health