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E9QAE4 (E9QAE4_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Name:Nsd1 Ensembl ENSMUSP00000097089 MGI 1276545
OrganismMus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000097089
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length2691 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214

Sequence similarities

Contains 1 post-SET domain. RuleBase RU004541

Contains SET domain. SAAS SAAS001214

Contains post-SET domain. SAAS SAAS001214

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000097089

Sequences

Sequence LengthMass (Da)Tools
E9QAE4 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: 9757638B75D6E773

FASTA2,691296,364
        10         20         30         40         50         60 
MDRTCELSRR NCLLSFSNPV NLDASEDKDS PFGNGQSNFS EPLNGCTMQL PTAASGTSQN 

        70         80         90        100        110        120 
AYGQDSPSCY IPLRRLQDLA SMINVEYLSG SADGSESFQD PAKSDSRAQS PIVCTSLSPG 

       130        140        150        160        170        180 
GPTALAMKQE PTCNNSPELQ LRVTKTTKNG FLHFENFTGV DDADVDSEMD PEQPVTEDES 

       190        200        210        220        230        240 
IEEIFEETQT NATCNYEPKS ENGVEVAMGS EQDSMPESRH GAVERPFLPL APQTEKQKNK 

       250        260        270        280        290        300 
QRSEVDGSNE KTALLPAPTS LGDTNVTVEE QFNSINLSFQ DDPDSSPSPL GNMLEIPGTS 

       310        320        330        340        350        360 
SPSTSQELPF CQPKKKSTPL KYEVGDLIWA KFKRRPWWPC RICSDPLINT HSKMKVANRR 

       370        380        390        400        410        420 
PYREYYVEAF GDPSEKAWVA GKAIVMFEGR HQFEELPVLR KRGKQKEKGY RHKVPQKILS 

       430        440        450        460        470        480 
KWEASVGLAE QYDVPKGSKN QKCVSSSVKL DSEEDMPFED CTNDPDSEHL LLNGCLKSLA 

       490        500        510        520        530        540 
FDSEHSADEK EKPCAKSRVR KSSDNIKRTS VKKDLVPFES RKEERRGKIP DNLGLDFISG 

       550        560        570        580        590        600 
GVSDKQASNE LSRIANSLTG SSTAPGSFLF SSSVQNTAKT DFETPDCDSL SGLSESALIS 

       610        620        630        640        650        660 
KHSGEKKKLQ PGQVCSSKVQ LCYVGAGDEE KRSNSVSVST TSDDGCSDLD PTEHNSGFQN 

       670        680        690        700        710        720 
SVLGITDAFD KTENALSVHK NETQYSRYPV TNRIKEKQKS LITNSHADHL MGSTKTMEPE 

       730        740        750        760        770        780 
TAELSQVNLS DLKISSPIPK PQPEFRNDGL TTKFSAPPGI RNENPLTKGG LANQTLLPLK 

       790        800        810        820        830        840 
CRQPKFRSIK CKHKESPAVA ETSATSEDLS LKCCSSDTNG SPLANISKSG KGEGLKLLNN 

       850        860        870        880        890        900 
MHEKTRDSSD IETAVVKHVL SELKELSYRS LSEDVSDSGT AKASKPLLFS SASSQNHIPI 

       910        920        930        940        950        960 
EPDYKFSTLL MMLKDMHDSK TKEQRLMTAQ NLASYRTPDR GDCSSGSPVG TSKVLVLGSS 

       970        980        990       1000       1010       1020 
TPNSEKPGDS TQDSVHQSPG GGDSALSGEL SSSLSSLASD KRELPACGKI RSNCIPRRNC 

      1030       1040       1050       1060       1070       1080 
GRAKPSSKLR ETISAQMVKP SVNPKALKTE RKRKFSRLPA VTLAANRLGN KESGSVNGPS 

      1090       1100       1110       1120       1130       1140 
RGGAEDPGKE EPLQQMDLLR NEDTHFSDVH FDSKAKQSDP DKNLEKEPSF ENRKGPELGS 

      1150       1160       1170       1180       1190       1200 
EMNTENDELH GVNQVVPKKR WQRLNQRRPK PGKRANRFRE KENSEGAFGV LLPADAVQKA 

      1210       1220       1230       1240       1250       1260 
REDYLEQRAP PTSKPEDSAA DPNHGSHSES VAPRLNVCEK SSVGMGDVEK ETGIPSLMPQ 

      1270       1280       1290       1300       1310       1320 
TKLPEPAIRS EKKRLRKPSK WLLEYTEEYD QIFAPKKKQK KVQEQVHKVS SRCEDESLLA 

      1330       1340       1350       1360       1370       1380 
RCQPSAQNKQ VDENSLISTK EEPPVLEREA PFLEGPLAQS DLGVTHAELP QLTLSVPVAP 

      1390       1400       1410       1420       1430       1440 
EASPRPALES EELLVKTPGN YESKRQRKPT KKLLESNDLD PGFMPKKGDL GLSRKCFEAS 

      1450       1460       1470       1480       1490       1500 
RSGNGIVESR ATSHLKEFSG GTTKIFDKPR KRKRQRLVTA RVHYKKVKKE DLTKDTPSSE 

      1510       1520       1530       1540       1550       1560 
GELLIHRTAA SPKEILEEGV EHDPGMSASK KLQVERGGGA ALKENVCQNC EKLGELLLCE 

      1570       1580       1590       1600       1610       1620 
AQCCGAFHLE CLGLPEMPRG KFICNECHTG IHTCFVCKQS GEDVKRCLLP LCGKFYHEEC 

      1630       1640       1650       1660       1670       1680 
VQKYPPTVTQ NKGFRCPLHI CITCHAANPA NVSASKGRLM RCVRCPVAYH ANDFCLAAGS 

      1690       1700       1710       1720       1730       1740 
KILASNSIIC PNHFTPRRGC RNHEHVNVSW CFVCSEGGSL LCCDSCPAAF HRECLNIDIP 

      1750       1760       1770       1780       1790       1800 
EGNWYCNDCK AGKKPHYREI VWVKVGRYRW WPAEICHPRA VPSNIDKMRH DVGEFPVLFF 

      1810       1820       1830       1840       1850       1860 
GSNDYLWTHQ ARVFPYMEGD VSSKDKMGKG VDGTYKKALQ EAAARFEELK AQKELRQLQE 

      1870       1880       1890       1900       1910       1920 
DRKNDKKPPP YKHIKVNRPI GRVQIFTADL SEIPRCNCKA TDENPCGIDS ECINRMLLYE 

      1930       1940       1950       1960       1970       1980 
CHPTVCPAGV RCQNQCFSKR QYPDVEIFRT LQRGWGLRTK TDIKKGEFVN EYVGELIDEE 

      1990       2000       2010       2020       2030       2040 
ECRARIRYAQ EHDITNFYML TLDKDRIIDA GPKGNYARFM NHCCQPNCET QKWSVNGDTR 

      2050       2060       2070       2080       2090       2100 
VGLFALSDIK AGTELTFNYN LECLGNGKTV CKCGAPNCSG FLGVRPKNQP IVTEEKSRKF 

      2110       2120       2130       2140       2150       2160 
KRKPHGKRRS QGEVTKERED ECFSCGDAGQ LVSCKKPGCP KVYHADCLNL TKRPAGKWEC 

      2170       2180       2190       2200       2210       2220 
PWHQCDVCGK EAASFCEMCP SSFCKQHREG MLFISKLDGR LSCTEHDPCG PNPLEPGEIR 

      2230       2240       2250       2260       2270       2280 
EYVPPTATSP PSPGTQPKEQ SSEMATQGPK KSDQPPTDAT QLLPLSKKAL TGSCQRPLLP 

      2290       2300       2310       2320       2330       2340 
ERPPERTDSS SHLLDRIRDL AGSGTKSQSL VSSQRPQDRP PAKEGPRPQP PDRASPMTRP 

      2350       2360       2370       2380       2390       2400 
SSSPSVSSLP LERPLRMTDS RLDKSIGAAS PKSQAVEKTP ASTGLRLSSP DRLLTTNSPK 

      2410       2420       2430       2440       2450       2460 
PQISDRPPEK SHASLTQRLP PPEKVLSAVV QSLVAKEKAL RPVDQNTQSK HRPAVVMDLI 

      2470       2480       2490       2500       2510       2520 
DLTPRQKERA ASPQEVTPQA DEKTAMLESS SWPSSKGLGH IPRATEKISV SESLQPSGKV 

      2530       2540       2550       2560       2570       2580 
AAPSEHPWQA VKSLTHARFL SPPSAKAFLY ESATQASGRT PVGAEQTPGP PSPAPGLVKQ 

      2590       2600       2610       2620       2630       2640 
VKQLSRGLTA KSGQSFRSLG KISASLPNEE KKLTTTEQSP WGLGKASPGA GLWPIVAGQT 

      2650       2660       2670       2680       2690 
LAQACWSAGG TQTLAQTCWS LGRGQDPKPE NAIQALNQAP SSRKCADSEK K 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC160958 Genomic DNA. No translation available.
RefSeqNP_032765.3. NM_008739.3.
XP_006517197.1. XM_006517134.1.
XP_006517198.1. XM_006517135.1.
XP_006517199.1. XM_006517136.1.
XP_006517200.1. XM_006517137.1.
XP_006517201.1. XM_006517138.1.
XP_006517202.1. XM_006517139.1.
XP_006517203.1. XM_006517140.1.
XP_006517204.1. XM_006517141.1.
XP_006517205.1. XM_006517142.1.
UniGeneMm.12964.
Mm.168965.

3D structure databases

ProteinModelPortalE9QAE4.
SMRE9QAE4. Positions 1754-1851, 1853-2083, 2119-2211.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEE9QAE4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000099490; ENSMUSP00000097089; ENSMUSG00000021488.
GeneID18193.
KEGGmmu:18193.
UCSCuc007qqd.1. mouse.

Organism-specific databases

CTD64324.
MGIMGI:1276545. Nsd1.

Phylogenomic databases

GeneTreeENSGT00740000114921.
KOK15588.
OMAECRTGIH.
OrthoDBEOG7Z69BG.
TreeFamTF329088.

Gene expression databases

ArrayExpressE9QAE4.
BgeeE9QAE4.

Family and domain databases

Gene3D3.30.40.10. 3 hits.
InterProIPR006560. AWS.
IPR003616. Post-SET_dom.
IPR000313. PWWP_dom.
IPR001214. SET_dom.
IPR019786. Zinc_finger_PHD-type_CS.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamPF00628. PHD. 1 hit.
PF00855. PWWP. 2 hits.
PF00856. SET. 1 hit.
[Graphical view]
SMARTSM00570. AWS. 1 hit.
SM00249. PHD. 5 hits.
SM00508. PostSET. 1 hit.
SM00293. PWWP. 2 hits.
SM00184. RING. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMSSF57903. SSF57903. 3 hits.
PROSITEPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50812. PWWP. 2 hits.
PS50280. SET. 1 hit.
PS01359. ZF_PHD_1. 2 hits.
PS50016. ZF_PHD_2. 2 hits.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSNSD1. mouse.
NextBio293540.
SOURCESearch...

Entry information

Entry nameE9QAE4_MOUSE
AccessionPrimary (citable) accession number: E9QAE4
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 16, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)