ID   E9Q9V5_MOUSE            Unreviewed;       267 AA.
AC   E9Q9V5;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 69.
DE   SubName: Full=Membrane-spanning 4-domains, subfamily A, member 7 {ECO:0000313|Ensembl:ENSMUSP00000025574.5};
GN   Name=Ms4a7 {ECO:0000313|Ensembl:ENSMUSP00000025574.5,
GN   ECO:0000313|MGI:MGI:1918846};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000025574.5, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000025574.5, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000025574.5,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0000313|Ensembl:ENSMUSP00000025574.5}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000025574.5};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the MS4A family.
CC       {ECO:0000256|ARBA:ARBA00009565}.
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DR   RefSeq; NP_001263327.1; NM_001276398.1.
DR   AlphaFoldDB; E9Q9V5; -.
DR   STRING; 10090.ENSMUSP00000025574; -.
DR   ProteomicsDB; 303653; -.
DR   Antibodypedia; 2586; 163 antibodies from 22 providers.
DR   DNASU; 109225; -.
DR   Ensembl; ENSMUST00000025574.11; ENSMUSP00000025574.5; ENSMUSG00000024672.12.
DR   GeneID; 109225; -.
DR   UCSC; uc033hjk.1; mouse.
DR   AGR; MGI:1918846; -.
DR   CTD; 58475; -.
DR   MGI; MGI:1918846; Ms4a7.
DR   VEuPathDB; HostDB:ENSMUSG00000024672; -.
DR   GeneTree; ENSGT00940000162779; -.
DR   InParanoid; E9Q9V5; -.
DR   OrthoDB; 5265300at2759; -.
DR   PhylomeDB; E9Q9V5; -.
DR   BioGRID-ORCS; 109225; 1 hit in 76 CRISPR screens.
DR   Proteomes; UP000000589; Chromosome 19.
DR   RNAct; E9Q9V5; Protein.
DR   Bgee; ENSMUSG00000024672; Expressed in stroma of bone marrow and 116 other cell types or tissues.
DR   ExpressionAtlas; E9Q9V5; baseline and differential.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005802; C:trans-Golgi network; ISO:MGI.
DR   GO; GO:0007166; P:cell surface receptor signaling pathway; IBA:GO_Central.
DR   InterPro; IPR007237; CD20-like.
DR   InterPro; IPR030417; MS4A.
DR   PANTHER; PTHR23320:SF8; MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MEMBER 7; 1.
DR   PANTHER; PTHR23320; MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED; 1.
DR   Pfam; PF04103; CD20; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        86..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        117..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        156..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        205..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   267 AA;  29217 MW;  34DD39D9CC9FCBA6 CRC64;
     MLQIQPTFGF QCSAIPICPT GNKNPGFICI PGTMRLQLGT KNIGWDCFPK DIIIHKREKT
     GHTYEKEDDL LIGVPSEATV LGTIQLLCAL ILASFGGILV SASYFNPEVS TTLISGYLFI
     GSLCFAIAGI LSIISEKIST KPFALSSLAS NVASSVVAVI GLFLFTYCLI ALGSAFPHCN
     SEKKFLSLLS YLKSHHWKNE DKNCYLAYVG AMSALGMMLL FTVLEVFLAG YSSIFWWKQV
     YSNKPGGTFF LPQSQDHTQL VKSNLLQ
//