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Protein
Submitted name:

Nuclear receptor corepressor 2

Gene

Ncor2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor corepressor 2Imported
Gene namesi
Name:Ncor2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:1337080. Ncor2.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

MaxQBiE9Q9V3.
PaxDbiE9Q9V3.
PeptideAtlasiE9Q9V3.
PRIDEiE9Q9V3.

PTM databases

iPTMnetiE9Q9V3.

Expressioni

Gene expression databases

BgeeiENSMUSG00000029478.
ExpressionAtlasiE9Q9V3. baseline and differential.
GenevisibleiE9Q9V3. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000083250.

Structurei

3D structure databases

ProteinModelPortaliE9Q9V3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini252 – 303SANTInterPro annotationAdd BLAST52
Domaini431 – 482SANTInterPro annotationAdd BLAST52

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1 – 31Sequence analysisAdd BLAST31
Coiled coili319 – 372Sequence analysisAdd BLAST54
Coiled coili480 – 507Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1878. Eukaryota.
ENOG410YDXP. LUCA.
GeneTreeiENSGT00840000129748.
KOiK06065.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR031557. N-CoR_GPS2_interact.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
[Graphical view]
PfamiPF15784. GPS2_interact. 1 hit.
PF00249. Myb_DNA-binding. 1 hit.
[Graphical view]
SMARTiSM00717. SANT. 2 hits.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS51293. SANT. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q9V3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRVDREITM VEQQISKLKK KQQQLEEEAA KPPEPEKPVS PPPIESKHRS
60 70 80 90 100
LVQIIYDENR KKAEAAHRIL EGLGPQVELP LYNQPSDTRQ YHENIKINQA
110 120 130 140 150
MRKKLILYFK RRNHARKQWE QRFCQRYDQL MEAWEKKVER IENNPRRRAK
160 170 180 190 200
ESKVREYYEK QFPEIRKQRE LQERMQSRVG QRGSGLSMSA ARSEHEVSEI
210 220 230 240 250
IDGLSEQENL EKQMRQLAVI PPMLYDADQQ RIKFINMNGL MDDPMKVYKD
260 270 280 290 300
RQVTNMWSEQ ERDTFREKFM QHPKNFGLIA SFLERKTVAE CVLYYYLTKK
310 320 330 340 350
NENYKSLVRR SYRRRGKSQQ QQQQQQQQQQ QQMARSSQEE KEEKEKEKEA
360 370 380 390 400
DKEEEKQDAE NEKEELSKEK TDDTSGEDND EKEAVASKGR KTANSQGRRK
410 420 430 440 450
GRITRSMANE ANHEETATPQ QSSELASMEM NESSRWTEEE METAKKGLLE
460 470 480 490 500
HGRNWSAIAR MVGSKTVSQC KNFYFNYKKR QNLDEILQQH KLKMEKERNA
510 520 530 540 550
RRKKKKTPAA ASEETAFPPA AEDEEMEASG ASANEEELAE EAEASQASGN
560 570 580 590 600
EVPRVGECSG PAAVNNSSDT ESVPSPRSEA TKDTGPKPTG TEALPAATQP
610 620 630 640 650
PVPPPEEPAV APAEPSPVPD ASGPPSPEPS PSPAAPPATV DKDEQEAPAA
660 670 680 690 700
PAPQTEDAKE QKSEAEEIDV GKPEEPEASE EPPESVKSDH KEETEEEPED
710 720 730 740 750
KAKGTEAIET VSEAPLKVEE AGSKAAVTKG SSSGATQDSD SSATCSADEV
760 770 780 790 800
DEPEGGDKGR LLSPRPSLLT PAGDPRASTS PQKPLDLKQL KQRAAAIPPI
810 820 830 840 850
VTKVHEPPRE DTVPPKPVPP VPPPTQHLQP EGDVSQQSGG SPRGKSRSPV
860 870 880 890 900
PPAEKEAEKP AFFPAFPTEG PKLPTEPPRW SSGLPFPIPP REVIKTSPHA
910 920 930 940 950
ADPSAFSYTP PGHPLPLGLH DSARPVLPRP PISNPPPLIS SAKHPGVLER
960 970 980 990 1000
QLGAISQQGM SVQLRVPHSE HAKAPMGPLT MGLPLAVDPK KLAPFSGVKQ
1010 1020 1030 1040 1050
EQLSPRGQAG PPESLGVPTA QETSVLRGTA LGSATSGSIT KGLPSTRAAD
1060 1070 1080 1090 1100
GPSYRGSITH GTPADVLYKG TISRIVGEDS PSRLDRARED TLPKGHVIYE
1110 1120 1130 1140 1150
GKKGHVLSYE GGMSVSQCSK EDGRSSSGPP HETAAPKRTY DMMEGRVGRT
1160 1170 1180 1190 1200
VTSASIEGLM GRAIPEQHSP HLKEQHHIRG SITQGIPRSY VEAQEDYLRR
1210 1220 1230 1240 1250
EAKLLKREGT PPPPPPPRDL TETYKPRPLD PLGPLKLKPT HEGVVATVKE
1260 1270 1280 1290 1300
AGRSIHEIPR EELRRTPELP LAPRPLKEGS ITQGTPLKYD SGAPSTGTKK
1310 1320 1330 1340 1350
HDVRSIIGSP GRPFPALHPL DIMADARALE RACYEESLKS RSGTSSGAGG
1360 1370 1380 1390 1400
SITRGAPVVV PELGKPRQSP LTYEDHGAPF TSHLPRGSPV TTREPTPRLQ
1410 1420 1430 1440 1450
EGSLLSSKAS QDRKLTSTPR EIAKSPHSTV PEHHPHPISP YEHLLRGVTG
1460 1470 1480 1490 1500
VDLYRGHIPL AFDPTSIPRG IPLEAAAAAY YLPRHLAPSP TYPHLYPPYL
1510 1520 1530 1540 1550
IRGYPDTAAL ENRQTIINDY ITSQQMHHNA ASAMAQRADM LRGLSPRESS
1560 1570 1580 1590 1600
LALNYAAGPR GIIDLSQVPH LPVLVPPTPG TPATAIDRLA YLPTAPPPFS
1610 1620 1630 1640 1650
SRHSSSPLSP GGPTHLAKPT ATSSSERERE RERERDKSIL TSTTTVEHAP
1660 1670 1680 1690 1700
IWRPGTEQSS GAGGSSRPAS HTHQHSPISP RTQDALQQRP SVLHNTSMKG
1710 1720 1730 1740 1750
VVTSVEPGTP TVLRWARSTS TSSPVRPAAT FPPATHCPLG GTLEGVYPTL
1760 1770 1780 1790 1800
MEPVLLPKET SRVARPERPR VDAGHAFLTK PPAREPASSP SKSSEPRSLA
1810 1820 1830 1840 1850
PPSSSHTAIA RTPAKNLAPH HASPDPPAPT SASDLHREKT QSKPFSIQEL
1860 1870 1880 1890 1900
ELRSLGYHSG AGYSPDGVEP ISPVSSPSLT HDKGLSKPLE ELEKSHLEGE
1910 1920 1930 1940 1950
LRHKQPGPMK LSAEAAHLPH LRPLPESQPS SSPLLQTAPG IKGHQRVVTL
1960 1970 1980 1990 2000
AQHISEVITQ DYTRHHPQQL SGPLPAPLYS FPGASCPVLD LRRPPSDLYL
2010 2020 2030 2040 2050
PPPDHGTPAR GSPHSEGGKR SPEPSKTSVL GSSEDAIEPV SPPEGMTEPG
2060 2070 2080 2090 2100
HARSTAYPLL YRDGEQGEPR MGSKSPGNTS QPPAFFSKLT ESNSAMVKSK
2110 2120 2130 2140 2150
KQEINKKLNT HNRNEPEYNI GQPGTEIFNM PAITGAGLMT CRSQAVQEHA
2160 2170 2180 2190 2200
STNMGLEAII RKALMGKYDQ WEEPPPLGAN AFNPLNASAS LPAAAMPITT
2210 2220 2230 2240 2250
ADGRSDHALT SPGGGGKAKV SGRPSSRKAK SPAPGLASGD RPPSVSSVHS
2260 2270 2280 2290 2300
EGDCNRRTPL TNRVWEDRPS SAGSTPFPYN PLIMRLQAGV MASPPPPGLA
2310 2320 2330
AGSGPLAGPH HAWDEEPKPL LCSQYETLSD SE
Length:2,332
Mass (Da):253,860
Last modified:April 5, 2011 - v1
Checksum:i99193B6D9CDD6AC2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132118 Genomic DNA. No translation available.
AC139377 Genomic DNA. No translation available.
RefSeqiNP_001240833.1. NM_001253904.1.
UniGeneiMm.278646.

Genome annotation databases

EnsembliENSMUST00000111393; ENSMUSP00000107024; ENSMUSG00000029478.
GeneIDi20602.
KEGGimmu:20602.
UCSCiuc008zqz.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132118 Genomic DNA. No translation available.
AC139377 Genomic DNA. No translation available.
RefSeqiNP_001240833.1. NM_001253904.1.
UniGeneiMm.278646.

3D structure databases

ProteinModelPortaliE9Q9V3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000083250.

PTM databases

iPTMnetiE9Q9V3.

Proteomic databases

MaxQBiE9Q9V3.
PaxDbiE9Q9V3.
PeptideAtlasiE9Q9V3.
PRIDEiE9Q9V3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000111393; ENSMUSP00000107024; ENSMUSG00000029478.
GeneIDi20602.
KEGGimmu:20602.
UCSCiuc008zqz.2. mouse.

Organism-specific databases

CTDi9612.
MGIiMGI:1337080. Ncor2.

Phylogenomic databases

eggNOGiKOG1878. Eukaryota.
ENOG410YDXP. LUCA.
GeneTreeiENSGT00840000129748.
KOiK06065.

Miscellaneous databases

ChiTaRSiNcor2. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000029478.
ExpressionAtlasiE9Q9V3. baseline and differential.
GenevisibleiE9Q9V3. MM.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR031557. N-CoR_GPS2_interact.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
[Graphical view]
PfamiPF15784. GPS2_interact. 1 hit.
PF00249. Myb_DNA-binding. 1 hit.
[Graphical view]
SMARTiSM00717. SANT. 2 hits.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS51293. SANT. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q9V3_MOUSE
AccessioniPrimary (citable) accession number: E9Q9V3
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 2, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.