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Protein
Submitted name:

Disks large homolog 1

Gene

Dlg1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Disks large homolog 1Imported
Gene namesi
Name:Dlg1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:107231 Dlg1

PTM / Processingi

Proteomic databases

MaxQBiE9Q9H0
PeptideAtlasiE9Q9H0
PRIDEiE9Q9H0

Expressioni

Gene expression databases

BgeeiENSMUSG00000022770
ExpressionAtlasiE9Q9H0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9Q9H0
SMRiE9Q9H0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 64L27InterPro annotationAdd BLAST61
Domaini224 – 311PDZInterPro annotationAdd BLAST88
Domaini319 – 406PDZInterPro annotationAdd BLAST88
Domaini466 – 547PDZInterPro annotationAdd BLAST82
Domaini581 – 651SH3InterPro annotationAdd BLAST71
Domaini722 – 897Guanylate kinase-likeInterPro annotationAdd BLAST176

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili851 – 871Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the MAGUK family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0708 Eukaryota
COG0194 LUCA
GeneTreeiENSGT00760000118866

Family and domain databases

InterProiView protein in InterPro
IPR016313 DLG1-like
IPR019590 DLG1_PEST_dom
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR020590 Guanylate_kinase_CS
IPR015143 L27_1
IPR004172 L27_dom
IPR036892 L27_dom_sf
IPR027417 P-loop_NTPase
IPR001478 PDZ
IPR019583 PDZ_assoc
IPR036034 PDZ_sf
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
PF09058 L27_1, 1 hit
PF10608 MAGUK_N_PEST, 1 hit
PF00595 PDZ, 3 hits
PF10600 PDZ_assoc, 1 hit
PF00018 SH3_1, 1 hit
PIRSFiPIRSF001741 MAGUK_DLGH, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SM00569 L27, 1 hit
SM01277 MAGUK_N_PEST, 1 hit
SM00228 PDZ, 3 hits
SM00326 SH3, 1 hit
SUPFAMiSSF101288 SSF101288, 1 hit
SSF50044 SSF50044, 2 hits
SSF50156 SSF50156, 3 hits
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit
PS51022 L27, 1 hit
PS50106 PDZ, 3 hits
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Complete.

E9Q9H0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVRKQDTQR ALHLLEEYRS KLSQTEDRQL RSSIERVINI FQSNLFQALI
60 70 80 90 100
DIQEFYEVTL LDNPKCVDHS KQCEPVQPVT TWEIASLPST AVTSETLPGS
110 120 130 140 150
LSPPVEKYRY QDEEVLPPEH ISPQVTNEVL GPELVHVSEK NLSEIENVHG
160 170 180 190 200
FVSHSHISPI KPTEAVPPSS PIVPVTPALP VPAESTVVLP SAPQANPPPV
210 220 230 240 250
LVNTDSLETP TYVNGTDADY EYEEITLERG NSGLGFSIAG GTDNPHIGDD
260 270 280 290 300
SSIFITKIIT GGAAAQDGRL RVNDCILRVN EADVRDVTHS KAVEALKEAG
310 320 330 340 350
SIVRLYVKRR KPASEKIMEI KLIKGPKGLG FSIAGGVGNQ HIPGDNSIYV
360 370 380 390 400
TKIIEGGAAH KDGKLQIGDK LLAVNSVCLE EVTHEEAVTA LKNTSDFVYL
410 420 430 440 450
KVAKPTSMYI NDGYAPPDIT NSSSQSVDNH VSPSSCLGQT PTSPARYSPI
460 470 480 490 500
SKAVLGDDEI TREPRKVVLH RGSTGLGFNI VGGEDGEGIF ISFILAGGPA
510 520 530 540 550
DLSGELRKGD RIISVNSVDL RAASHEQAAA ALKNAGQAVT IVAQYRPEEY
560 570 580 590 600
SRFEAKIHDL REQMMNSSVS SGSGSLRTSQ KRSLYVRALF DYDKTKDSGL
610 620 630 640 650
PSQGLNFRFG DILHVINASD DEWWQARQVT PDGESDEVGV IPSKRRVEKK
660 670 680 690 700
ERARLKTVKF NSKTRGDKGE IPDDMGSKGL KHVTSNASDS ESSYHEYGCS
710 720 730 740 750
KGGQEEYVLS YEPVNQQEVN YTRPVIILGP MKDRVNDDLI SEFPDKFGSC
760 770 780 790 800
VPHTTRPKRD YEVDGRDYHF VTSREQMEKD IQEHKFIEAG QYNNHLYGTS
810 820 830 840 850
VQSVRAVAEK GKHCILDVSG NAIKRLQIAQ LYPISIFIKP KSMENIMEMN
860 870 880 890 900
KRLTEEQARK TFERAMKLEQ EFTEHFTAIV QGDTLEDIYN QVKQIIEEQS
910
GPYIWVPAKE KL
Length:912
Mass (Da):100,825
Last modified:April 5, 2011 - v1
Checksum:i88EE7BA87F236F80
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126055 Genomic DNA No translation available.
AC129214 Genomic DNA No translation available.
RefSeqiXP_006521829.1, XM_006521766.3
UniGeneiMm.382

Genome annotation databases

EnsembliENSMUST00000115201; ENSMUSP00000110855; ENSMUSG00000022770
GeneIDi13383

Similar proteinsi

Entry informationi

Entry nameiE9Q9H0_MOUSE
AccessioniPrimary (citable) accession number: E9Q9H0
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: March 28, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health