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E9Q9B8

- E9Q9B8_MOUSE

UniProt

E9Q9B8 - E9Q9B8_MOUSE

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Protein
Submitted name: Clusterin
Gene
Clu
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. protein binding Source: MGI
Complete GO annotation...

GO - Biological processi

  1. chaperone-mediated protein folding Source: Ensembl
  2. intrinsic apoptotic signaling pathway Source: Ensembl
  3. negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage Source: Ensembl
  4. negative regulation of protein homooligomerization Source: Ensembl
  5. positive regulation of NF-kappaB transcription factor activity Source: Ensembl
  6. positive regulation of apoptotic process Source: Ensembl
  7. positive regulation of intrinsic apoptotic signaling pathway Source: Ensembl
  8. positive regulation of proteasomal ubiquitin-dependent protein catabolic process Source: Ensembl
  9. positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process Source: Ensembl
  10. protein stabilization Source: Ensembl
  11. response to misfolded protein Source: Ensembl
  12. response to virus Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ClusterinImported
Gene namesi
Name:CluImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 14

Organism-specific databases

MGIiMGI:88423. Clu.

Subcellular locationi

GO - Cellular componenti

  1. extracellular matrix Source: Ensembl
  2. mitochondrion Source: Ensembl
  3. perinuclear region of cytoplasm Source: Ensembl
  4. spherical high-density lipoprotein particle Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiE9Q9B8.
BgeeiE9Q9B8.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063668.

Family and domain databases

InterProiIPR016016. Clusterin.
IPR000753. Clusterin-like.
IPR016014. Clusterin_N.
[Graphical view]
PANTHERiPTHR10970:SF1. PTHR10970:SF1. 1 hit.
PfamiPF01093. Clusterin. 1 hit.
[Graphical view]
SMARTiSM00030. CLb. 1 hit.
[Graphical view]
PROSITEiPS00492. CLUSTERIN_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E9Q9B8-1 [UniParc]FASTAAdd to Basket

« Hide

MKILLLCVAL LLIWDNGMVL GEQEVSDNEL QELSTQGSRY INKEIQNAVQ    50
GVKHIKTLIE KTNAERKSLL NSLEEAKKKK EDALEDTRDS EMKLKAFPEV 100
CNETMMALWE ECKPCLKHTC MKFYARVCRS GSGLVGQQLE EFLNQSSPFY 150
FWMNGDRIDS LLESDRQQSQ VLDAMQDSFA RASGIIDTLF QDRFFARELH 200
DPH 203
Length:203
Mass (Da):23,372
Last modified:April 5, 2011 - v1
Checksum:i478E6C0D3B24208C
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei203 – 2031Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC126444 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000128539; ENSMUSP00000121485; ENSMUSG00000022037.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC126444 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000128539 ; ENSMUSP00000121485 ; ENSMUSG00000022037 .

Organism-specific databases

MGIi MGI:88423. Clu.

Phylogenomic databases

GeneTreei ENSGT00530000063668.

Miscellaneous databases

ChiTaRSi CLU. mouse.
NextBioi 35555740.
SOURCEi Search...

Gene expression databases

ArrayExpressi E9Q9B8.
Bgeei E9Q9B8.

Family and domain databases

InterProi IPR016016. Clusterin.
IPR000753. Clusterin-like.
IPR016014. Clusterin_N.
[Graphical view ]
PANTHERi PTHR10970:SF1. PTHR10970:SF1. 1 hit.
Pfami PF01093. Clusterin. 1 hit.
[Graphical view ]
SMARTi SM00030. CLb. 1 hit.
[Graphical view ]
PROSITEi PS00492. CLUSTERIN_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q9B8_MOUSE
AccessioniPrimary (citable) accession number: E9Q9B8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 9, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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