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Protein
Submitted name:

Cadherin 18

Gene

Cdh18

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumSAAS annotation

Enzyme and pathway databases

ReactomeiR-MMU-418990 Adherens junctions interactions

Names & Taxonomyi

Protein namesi
Submitted name:
Cadherin 18Imported
Gene namesi
Name:Cdh18Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:1344366 Cdh18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500324585225 – 574Sequence analysisAdd BLAST550

Proteomic databases

PeptideAtlasiE9Q941
PRIDEiE9Q941

Expressioni

Gene expression databases

BgeeiENSMUSG00000040420
ExpressionAtlasiE9Q941 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9Q941
SMRiE9Q941
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini76 – 157CAInterPro annotationAdd BLAST82
Domaini181 – 266CAInterPro annotationAdd BLAST86
Domaini290 – 382CAInterPro annotationAdd BLAST93
Domaini405 – 486CAInterPro annotationAdd BLAST82

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA
GeneTreeiENSGT00760000118954

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin
IPR015919 Cadherin-like
IPR020894 Cadherin_CS
PfamiView protein in Pfam
PF00028 Cadherin, 4 hits
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 4 hits
SUPFAMiSSF49313 SSF49313, 5 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 2 hits

Sequencei

Sequence statusi: Complete.

E9Q941-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRITSTSCIC PVLVCLCFVQ RCYGTAHHSS IKVTRNQTKH TEGETEVHHR
60 70 80 90 100
PKRGWVWNQF FVLEEHMGPD PQYVGKLHSN SDKGDGSVKY ILTGEGAGTI
110 120 130 140 150
FIIDDTTGDI HSTKSLDREQ KTHYVLHAQA IDRRTNKPLE PESEFIIKVQ
160 170 180 190 200
DINDNAPKFT DGPYIVTVPE MSDMGTSVLQ VTATDADDPT YGNSARVVYS
210 220 230 240 250
ILQGQPYFSV DPKTGVIRTA LHNMDREARE HYSVVIQAKD MAGQVGGLSG
260 270 280 290 300
STTVNITLTD VNDNPPRFPQ KHYQLYVPES AQVGSAVGKI KANDADTGSN
310 320 330 340 350
ADMTYSITNG DGIGVFSIST DKDTREGILS LKKPLNYEKK KSYTLNIEGA
360 370 380 390 400
NTHLDFRFSH LGPFKDATML KVIVGDVDEP PLFSMPSYVM EVYENAKIGT
410 420 430 440 450
IVGTVLAQDP DSANSLVRYF INHSTEEERF FNIDANTGTI KTSKVLDREE
460 470 480 490 500
TPWYNITVTA SENDNPDLLS HVSVGIRVLD VNDNPPELAR EYDIVVCENS
510 520 530 540 550
KPGQVIHTIT ATDKDDFANG PRFHFFLDER LPMNPNFTLK DNEAAAPSPS
560 570
GFVHAREMGA CGPAMQKPSC PPLV
Length:574
Mass (Da):63,450
Last modified:April 5, 2011 - v1
Checksum:iF7FB7E9A82DC4172
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121357 Genomic DNA No translation available.
AC124467 Genomic DNA No translation available.
AC133461 Genomic DNA No translation available.
AC134595 Genomic DNA No translation available.
AC134864 Genomic DNA No translation available.
AC137875 Genomic DNA No translation available.
AC157478 Genomic DNA No translation available.
AC158771 Genomic DNA No translation available.
AC172891 Genomic DNA No translation available.
RefSeqiXP_006520161.1, XM_006520098.3
UniGeneiMm.241965

Genome annotation databases

EnsembliENSMUST00000165614; ENSMUSP00000128643; ENSMUSG00000040420
GeneIDi320865
UCSCiuc007vir.1 mouse

Similar proteinsi

Entry informationi

Entry nameiE9Q941_MOUSE
AccessioniPrimary (citable) accession number: E9Q941
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 23, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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