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E9Q8Y5

- E9Q8Y5_MOUSE

UniProt

E9Q8Y5 - E9Q8Y5_MOUSE

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Protein
Submitted name:

Clusterin

Gene
Clu
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. protein binding Source: MGI

GO - Biological processi

  1. chaperone-mediated protein folding Source: Ensembl
  2. intrinsic apoptotic signaling pathway Source: Ensembl
  3. negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage Source: Ensembl
  4. negative regulation of protein homooligomerization Source: Ensembl
  5. positive regulation of apoptotic process Source: Ensembl
  6. positive regulation of intrinsic apoptotic signaling pathway Source: Ensembl
  7. positive regulation of NF-kappaB transcription factor activity Source: Ensembl
  8. positive regulation of proteasomal ubiquitin-dependent protein catabolic process Source: Ensembl
  9. positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process Source: Ensembl
  10. protein stabilization Source: Ensembl
  11. response to misfolded protein Source: Ensembl
  12. response to virus Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
ClusterinImported
Gene namesi
Name:CluImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 14

Organism-specific databases

MGIiMGI:88423. Clu.

Subcellular locationi

GO - Cellular componenti

  1. extracellular matrix Source: Ensembl
  2. mitochondrion Source: Ensembl
  3. perinuclear region of cytoplasm Source: Ensembl
  4. spherical high-density lipoprotein particle Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiE9Q8Y5.
BgeeiE9Q8Y5.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063668.

Family and domain databases

InterProiIPR016016. Clusterin.
IPR000753. Clusterin-like.
IPR016014. Clusterin_N.
[Graphical view]
PANTHERiPTHR10970:SF1. PTHR10970:SF1. 1 hit.
PfamiPF01093. Clusterin. 1 hit.
[Graphical view]
SMARTiSM00030. CLb. 1 hit.
[Graphical view]
PROSITEiPS00492. CLUSTERIN_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E9Q8Y5-1 [UniParc]FASTAAdd to Basket

« Hide

MKILLLCVAL LLIWDNGMVL GEQEVSDNEL QELSTQGSRY INKEIQNAVQ    50
GVKHIKTLIE KTNAERKSLL NSLEEAKKKK EDALEDTRDS EMKLKAFPEV 100
CNETMMALWE ECKPCLKHTC MKFYARVCRS GSGLVGQQLE EFLNQSSPFY 150
FWMNGDRIDS LLESDRQQSQ VLDAMQDSFA RASGIIDTLF QDRFFARELH 200
DPHYFSPIGF PHKRPHFLYP KSRLVRSLMS PSHYGPPSFH NMFQPFFEMI 250
HQAQQAMDVQ LHSPA 265
Length:265
Mass (Da):30,651
Last modified:April 5, 2011 - v1
Checksum:iFF78F9FF7B953D0E
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei265 – 2651Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC126444 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000153460; ENSMUSP00000121633; ENSMUSG00000022037.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC126444 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000153460 ; ENSMUSP00000121633 ; ENSMUSG00000022037 .

Organism-specific databases

MGIi MGI:88423. Clu.

Phylogenomic databases

GeneTreei ENSGT00530000063668.

Miscellaneous databases

ChiTaRSi CLU. mouse.
NextBioi 35555684.
SOURCEi Search...

Gene expression databases

ArrayExpressi E9Q8Y5.
Bgeei E9Q8Y5.

Family and domain databases

InterProi IPR016016. Clusterin.
IPR000753. Clusterin-like.
IPR016014. Clusterin_N.
[Graphical view ]
PANTHERi PTHR10970:SF1. PTHR10970:SF1. 1 hit.
Pfami PF01093. Clusterin. 1 hit.
[Graphical view ]
SMARTi SM00030. CLb. 1 hit.
[Graphical view ]
PROSITEi PS00492. CLUSTERIN_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q8Y5_MOUSE
AccessioniPrimary (citable) accession number: E9Q8Y5
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 9, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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