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Protein
Submitted name:

DENN/MADD domain-containing 4A

Gene

Dennd4a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

ReactomeiR-MMU-8876198 RAB GEFs exchange GTP for GDP on RABs

Names & Taxonomyi

Protein namesi
Submitted name:
DENN/MADD domain-containing 4AImported
Gene namesi
Name:Dennd4aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:2142979 Dennd4a

PTM / Processingi

Proteomic databases

MaxQBiE9Q8V6
PaxDbiE9Q8V6
PeptideAtlasiE9Q8V6
PRIDEiE9Q8V6

PTM databases

iPTMnetiE9Q8V6
PhosphoSitePlusiE9Q8V6

Expressioni

Gene expression databases

BgeeiENSMUSG00000053641
ExpressionAtlasiE9Q8V6 baseline and differential
GenevisibleiE9Q8V6 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000037915

Structurei

3D structure databases

SMRiE9Q8V6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 200MABPInterPro annotationAdd BLAST159
Domaini192 – 642UDENNInterPro annotationAdd BLAST451
Repeati810 – 844PPRPROSITE-ProRule annotationAdd BLAST35

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili514 – 534Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2127 Eukaryota
ENOG410YREK LUCA
GeneTreeiENSGT00760000118819
InParanoidiE9Q8V6
KOiK20163
OMAiFLCFMAS
OrthoDBiEOG091G00CV
TreeFamiTF313237

Family and domain databases

Gene3Di1.25.40.10, 1 hit
InterProiView protein in InterPro
IPR001194 cDENN_dom
IPR005112 dDENN_dom
IPR023341 MABP
IPR002885 Pentatricopeptide_repeat
IPR011990 TPR-like_helical_dom_sf
IPR037516 Tripartite_DENN
IPR005113 uDENN_dom
PfamiView protein in Pfam
PF03455 dDENN, 1 hit
PF02141 DENN, 1 hit
PF03456 uDENN, 1 hit
SMARTiView protein in SMART
SM00801 dDENN, 1 hit
SM00799 DENN, 1 hit
SM00800 uDENN, 1 hit
TIGRFAMsiTIGR00756 PPR, 1 hit
PROSITEiView protein in PROSITE
PS50211 DENN, 1 hit
PS51498 MABP, 1 hit
PS51375 PPR, 1 hit

Sequencei

Sequence statusi: Complete.

E9Q8V6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIEDKGPRVA DYFVVAGLTD ISKPLEEEIH FNDACHKVAK PKEPITDVSV
60 70 80 90 100
IIKSLGEEVP RDYVCIDVTP TGLSADLNNG SLVGPQIYLC YKRGRDKPPL
110 120 130 140 150
TDLGVLYDWK ERLKQGCEII QSTPYGRPAN ISGSTSSQRI YITYRRASEN
160 170 180 190 200
TTQNTLAVTD ICIIIPSKGE SPPHTFCKVD KNLSNSMWGS AVYLCYKKSV
210 220 230 240 250
AKTNTISYKA GLICRYPQED YESFSLPESV PLFCLPMGAT IECWPPDSKY
260 270 280 290 300
PLPVFSTFVL TGASAEKVYG AAIQFYEPYP EENLTEKQRL LLGLTSLVDG
310 320 330 340 350
KSDSTRTIHT NKCICLLSHW PFFDAFRKFL TFLYRYSISG PHALPIEKHI
360 370 380 390 400
SHFMHKVPFP SPQRPRILVQ LSPHDNLILS QPVSSPLPLS GGKFSTLLQN
410 420 430 440 450
LGPENAVTLL VFAVTEHKIL IHSLRPSVLT SVTEALVSMI FPFHWPCPYV
460 470 480 490 500
PLCPLALADV LSAPCPFIVG IDSRYFDLYD PPPDVSCVDL DTNTISQTGD
510 520 530 540 550
KKNVAWKILP KKPCKNLMNT LNNLHQQLAK LQQRPRDDGL MDLAMNDYDF
560 570 580 590 600
NSGKRLHMID LEIQEAFLFF MASILKGYRS YLRPITQAPS ETATDATSLF
610 620 630 640 650
ALQAFLRSRD RSHQKFYNMM TKTQMFIRFI EECSFVSDKD ASLAFFDDCV
660 670 680 690 700
DKVDTDKSGE VRLIELDASF KSEHTVFVTP PEIPHLPNGE EPPLQYSYNG
710 720 730 740 750
FPVLRNNLFE RPEGFLQARK NKLPSKPSSP GSPSPMFRRT KQEIKSAHKI
760 770 780 790 800
AKRYSSIPQM WSRCLLRHCY GLWFICLPAY VKVCHSKVRA LKTAYDVLKK
810 820 830 840 850
MQLKKMDPPD EVCYRILMQL CGQYDQPVLA VRVLFEMQKA GIDPNAITYG
860 870 880 890 900
YYNKAVLEST WPSRSRSGYF LWTKVRNVVL GVAQFKRALK KHPHLPQTAL
910 920 930 940 950
SGGRSDLGYN SLSKDNVRRE GPSTEDIQGE KEKRGSDSSS LSENESTKGS
960 970 980 990 1000
AECLPTLSYQ RASTIVRLNG AHNDSAGKTS GECEESTPEL LLMPSLEDTN
1010 1020 1030 1040 1050
EAQTTPSRCF RKRHKSDDGS HLQQQMPWGS RNRNLSGGVL MGFMLNRTNQ
1060 1070 1080 1090 1100
ETSPGEMVEK LGADAKILSN VISKSTRPNS LDIGKPPARS KRDSLEKESS
1110 1120 1130 1140 1150
DDDTPFHGSN CLDKVESPVI FDLEDLDTET DGSKVGGVAA QNPKRLQRRN
1160 1170 1180 1190 1200
SSFSVKPSEK TDVVTGFDPL SLLVAETEQQ QKVEEEEDED DNKSVSTPSA
1210 1220 1230 1240 1250
RRNLAEEIEM YMNNMSSPLT SRTPSIDLQR ACDDKLTNKK SPTLVKACRR
1260 1270 1280 1290 1300
SSLPPNSPRP VRLTKSKSYT KSEERPRDRL WSSPAFSPTC PFREGSQETL
1310 1320 1330 1340 1350
AHSSPSFNLD TLLVPKLDVL RHSVFTAGKG VAEKASKWYS RFTMYTTSSK
1360 1370 1380 1390 1400
DQSSDRTSLS SVGAQDSEST SLTDEDVCHE LEGATSSQES SAASGTKGID
1410 1420 1430 1440 1450
VSRASLGSSA SLEGSLSKFA LPGKSETASS LNTSNANIFQ NYAMEVLISS
1460 1470 1480 1490 1500
CSRCRTCDCL VHDEEIMAGW TADDSNLNTT CPFCGNLFLP FLNVEIRDLR
1510 1520 1530 1540 1550
RPGRYFLKSS SSTETMHFAS RTRQSCISAS ASGLDTSSLS VQGNFDLNNK
1560 1570 1580 1590 1600
SKLQENPCAR SIQIPAHRSK TVVSKCPLFP MARSISTCGP LDKDDPGGQK
1610 1620 1630 1640 1650
LIPTGSLPAT LQGHTDSLGL EWHLPSPDPV TVPYLSPLVV WKELESLLEN
1660 1670 1680 1690 1700
EGDHAITVAD FVDHHPIVFW NLVWYFRRLD LPSNLPGLIL SSEHCNKYSK
1710 1720 1730 1740 1750
IPRHCMSEDS KYVLIQMLWD NMKLHQDPGQ PLYILWNAHS QNRTLLFETQ
1760 1770 1780 1790 1800
KYPMVHLLQK GDDSFNQELL KSMVKSIKMN DVYGPMSQIL ETLNKCPHFK
1810 1820 1830 1840 1850
RQRSLYREIL FLSLVALGRE NIDIDAFDKE YKMAYDRLTP SQVKSTHNCD
1860
RPPSTGVMEC RKTFGEPYL
Length:1,869
Mass (Da):209,302
Last modified:April 5, 2011 - v1
Checksum:i44D9DEC3AFD605AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140243 Genomic DNA No translation available.
RefSeqiNP_001156389.1, NM_001162917.1
XP_006510804.1, XM_006510741.2
XP_006510805.1, XM_006510742.2
XP_006510806.1, XM_006510743.2
XP_006510807.1, XM_006510744.2
XP_006510808.1, XM_006510745.2
XP_011240953.1, XM_011242651.2
XP_011240954.1, XM_011242652.2
XP_011240955.1, XM_011242653.2
UniGeneiMm.222473

Genome annotation databases

EnsembliENSMUST00000038890; ENSMUSP00000037915; ENSMUSG00000053641
GeneIDi102442
KEGGimmu:102442
UCSCiuc009qcj.2 mouse

Similar proteinsi

Entry informationi

Entry nameiE9Q8V6_MOUSE
AccessioniPrimary (citable) accession number: E9Q8V6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 25, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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