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E9Q8V2

- E9Q8V2_MOUSE

UniProt

E9Q8V2 - E9Q8V2_MOUSE

Protein
Submitted name:

GTPase KRas

Gene

Kras

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. GTPase activity Source: MGI
    2. GTP binding Source: UniProtKB-KW
    3. protein complex binding Source: MGI

    GO - Biological processi

    1. actin cytoskeleton organization Source: MGI
    2. epithelial tube branching involved in lung morphogenesis Source: MGI
    3. negative regulation of cell differentiation Source: MGI
    4. negative regulation of neuron apoptotic process Source: MGI
    5. positive regulation of cell proliferation Source: MGI
    6. positive regulation of Rac protein signal transduction Source: MGI
    7. Ras protein signal transduction Source: MGI
    8. regulation of long-term neuronal synaptic plasticity Source: MGI
    9. regulation of synaptic transmission, GABAergic Source: MGI
    10. striated muscle cell differentiation Source: MGI
    11. visual learning Source: MGI

    Keywords - Ligandi

    GTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    GTPase KRasImported
    Gene namesi
    Name:KrasImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 6

    Organism-specific databases

    MGIiMGI:96680. Kras.

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: MGI

    PTM / Processingi

    Proteomic databases

    PRIDEiE9Q8V2.

    Expressioni

    Gene expression databases

    ArrayExpressiE9Q8V2.
    BgeeiE9Q8V2.

    Structurei

    3D structure databases

    ProteinModelPortaliE9Q8V2.
    SMRiE9Q8V2. Positions 1-37.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00750000117221.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR027417. P-loop_NTPase.
    IPR001806. Small_GTPase.
    IPR020849. Small_GTPase_Ras.
    [Graphical view]
    PANTHERiPTHR24070. PTHR24070. 1 hit.
    PfamiPF00071. Ras. 1 hit.
    [Graphical view]
    PRINTSiPR00449. RASTRNSFRMNG.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS51421. RAS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9Q8V2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIERTN              40
    Length:40
    Mass (Da):4,408
    Last modified:April 5, 2011 - v1
    Checksum:i43F6602AA5B411D7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC157091 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000156486; ENSMUSP00000119414; ENSMUSG00000030265.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC157091 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E9Q8V2.
    SMRi E9Q8V2. Positions 1-37.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi E9Q8V2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000156486 ; ENSMUSP00000119414 ; ENSMUSG00000030265 .

    Organism-specific databases

    MGIi MGI:96680. Kras.

    Phylogenomic databases

    GeneTreei ENSGT00750000117221.

    Miscellaneous databases

    ChiTaRSi KRAS. mouse.
    NextBioi 35555670.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9Q8V2.
    Bgeei E9Q8V2.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR027417. P-loop_NTPase.
    IPR001806. Small_GTPase.
    IPR020849. Small_GTPase_Ras.
    [Graphical view ]
    PANTHERi PTHR24070. PTHR24070. 1 hit.
    Pfami PF00071. Ras. 1 hit.
    [Graphical view ]
    PRINTSi PR00449. RASTRNSFRMNG.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS51421. RAS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9Q8V2_MOUSE
    AccessioniPrimary (citable) accession number: E9Q8V2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3