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Protein
Submitted name:

Hexokinase-3

Gene

Hk3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotation, Transferase
Biological processGlycolysisSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase-3Imported
Gene namesi
Name:Hk3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 13

Organism-specific databases

MGIiMGI:2670962 Hk3

Subcellular locationi

PTM / Processingi

Proteomic databases

MaxQBiE9Q8S8
PeptideAtlasiE9Q8S8
PRIDEiE9Q8S8

Expressioni

Gene expression databases

BgeeiENSMUSG00000025877
ExpressionAtlasiE9Q8S8 baseline and differential
GenevisibleiE9Q8S8 MM

Structurei

3D structure databases

ProteinModelPortaliE9Q8S8
SMRiE9Q8S8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 228Hexokinase_1InterPro annotationAdd BLAST196
Domaini236 – 433Hexokinase_2InterPro annotationAdd BLAST198
Domaini436 – 627Hexokinase_1InterPro annotationAdd BLAST192
Domaini633 – 867Hexokinase_2InterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the hexokinase family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1369 Eukaryota
COG5026 LUCA
GeneTreeiENSGT00390000017159

Family and domain databases

InterProiView protein in InterPro
IPR001312 Hexokinase
IPR019807 Hexokinase_BS
IPR022673 Hexokinase_C
IPR022672 Hexokinase_N
PANTHERiPTHR19443 PTHR19443, 4 hits
PfamiView protein in Pfam
PF00349 Hexokinase_1, 2 hits
PF03727 Hexokinase_2, 2 hits
PROSITEiView protein in PROSITE
PS00378 HEXOKINASE_1, 2 hits
PS51748 HEXOKINASE_2, 2 hits

Sequencei

Sequence statusi: Complete.

E9Q8S8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATIGPSGLH PGERASVCPH EGVPRPSGSL ELECLQQFKV TRTQLQQIQA
60 70 80 90 100
SLLCSMEQAL KGQDSPAPSV RMLPTYVRST PHGTEQGDFL VLELGATGAS
110 120 130 140 150
LRVLWVTLTG TKECRVEPRS REFVIPQEVI LGAGQQLFDF AARCLSEFLD
160 170 180 190 200
AYPVENQGLK LGFNFSFPCH QTGLDRSTLI SWTKGFRCSG VEGQDVVQLL
210 220 230 240 250
RDAIQRQGTY RIDVVAMVND TVGTMMGCEL GTRPCEVGLI VDTGTNACYM
260 270 280 290 300
EEARHVAALD EDRGRTCVSI EWGSFYDEDA LGPVLTTFDS ALDRESLTPG
310 320 330 340 350
AQRFEKMIGG LYLGELVRLV LVHLTQHGVL FDGCASPALL SQGCILLDHV
360 370 380 390 400
AEMEDTATGT ARVHTILQDL GLSPRASDAE LVQYVCVAVC TRAAQLCAAA
410 420 430 440 450
LAAVLSRLQH SREQQTLQVA VATGGRVFER HPRRILEETL APFQLTLEQM
460 470 480 490 500
TVVQAQMREA MIRGLQGEAS SLRMLPTYVR ATPDGSERGD FLALDLGGTN
510 520 530 540 550
FRVLLVRVAE GSVQIINQVY SIPECRAQGS GQKLFDHIVD CIVDFQKRQG
560 570 580 590 600
LSGQSLPLGF TFSFPCKQLG LDQGILLNWT KGFNASGCEG QDVVYLLREA
610 620 630 640 650
IRRRQAVELN VVAIVNDTVG TMMSCGYDDP RCEMGLIVGT GTNACYMEEL
660 670 680 690 700
RNVASVPGDS GLMCINMEWG AFGDDGSLGT LSTRFDTSVD QASINPGKQR
710 720 730 740 750
FEKMISGMYL GEIVRHILLH LTNLGVLFRG QKTQCLQARD IFKTKFLSEI
760 770 780 790 800
ESDSLALRQV RAILEDLGLT LTSDDALMVL EVCQAVSRRA AQLCGAGVAA
810 820 830 840 850
VVEKIRENRG LQELTVSVGV DGTLYKLHPH FSKLVSATVR KLAPQCTVTF
860 870
LQSEDGSGKG AALVTAVACR LTQMAHV
Length:877
Mass (Da):95,424
Last modified:April 5, 2011 - v1
Checksum:i85B718A47ACA24CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154610 Genomic DNA No translation available.
RefSeqiNP_001193320.1, NM_001206391.1
UniGeneiMm.267479

Genome annotation databases

EnsembliENSMUST00000123097; ENSMUSP00000116717; ENSMUSG00000025877
GeneIDi212032
UCSCiuc007qps.2 mouse

Similar proteinsi

Entry informationi

Entry nameiE9Q8S8_MOUSE
AccessioniPrimary (citable) accession number: E9Q8S8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 25, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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