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E9Q8S8

- E9Q8S8_MOUSE

UniProt

E9Q8S8 - E9Q8S8_MOUSE

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Protein
Submitted name:

Hexokinase-3

Gene

Hk3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. fructokinase activity Source: RefGenome
  3. glucokinase activity Source: RefGenome
  4. mannokinase activity Source: RefGenome

GO - Biological processi

  1. carbohydrate phosphorylation Source: GOC
  2. cellular glucose homeostasis Source: RefGenome
  3. glucose 6-phosphate metabolic process Source: GOC
  4. glycolytic process Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase-3Imported
Gene namesi
Name:Hk3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 13

Organism-specific databases

MGIiMGI:2670962. Hk3.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: RefGenome
  2. mitochondrion Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiE9Q8S8.
ExpressionAtlasiE9Q8S8. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9Q8S8.
SMRiE9Q8S8. Positions 35-873.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000017159.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q8S8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MATIGPSGLH PGERASVCPH EGVPRPSGSL ELECLQQFKV TRTQLQQIQA
60 70 80 90 100
SLLCSMEQAL KGQDSPAPSV RMLPTYVRST PHGTEQGDFL VLELGATGAS
110 120 130 140 150
LRVLWVTLTG TKECRVEPRS REFVIPQEVI LGAGQQLFDF AARCLSEFLD
160 170 180 190 200
AYPVENQGLK LGFNFSFPCH QTGLDRSTLI SWTKGFRCSG VEGQDVVQLL
210 220 230 240 250
RDAIQRQGTY RIDVVAMVND TVGTMMGCEL GTRPCEVGLI VDTGTNACYM
260 270 280 290 300
EEARHVAALD EDRGRTCVSI EWGSFYDEDA LGPVLTTFDS ALDRESLTPG
310 320 330 340 350
AQRFEKMIGG LYLGELVRLV LVHLTQHGVL FDGCASPALL SQGCILLDHV
360 370 380 390 400
AEMEDTATGT ARVHTILQDL GLSPRASDAE LVQYVCVAVC TRAAQLCAAA
410 420 430 440 450
LAAVLSRLQH SREQQTLQVA VATGGRVFER HPRRILEETL APFQLTLEQM
460 470 480 490 500
TVVQAQMREA MIRGLQGEAS SLRMLPTYVR ATPDGSERGD FLALDLGGTN
510 520 530 540 550
FRVLLVRVAE GSVQIINQVY SIPECRAQGS GQKLFDHIVD CIVDFQKRQG
560 570 580 590 600
LSGQSLPLGF TFSFPCKQLG LDQGILLNWT KGFNASGCEG QDVVYLLREA
610 620 630 640 650
IRRRQAVELN VVAIVNDTVG TMMSCGYDDP RCEMGLIVGT GTNACYMEEL
660 670 680 690 700
RNVASVPGDS GLMCINMEWG AFGDDGSLGT LSTRFDTSVD QASINPGKQR
710 720 730 740 750
FEKMISGMYL GEIVRHILLH LTNLGVLFRG QKTQCLQARD IFKTKFLSEI
760 770 780 790 800
ESDSLALRQV RAILEDLGLT LTSDDALMVL EVCQAVSRRA AQLCGAGVAA
810 820 830 840 850
VVEKIRENRG LQELTVSVGV DGTLYKLHPH FSKLVSATVR KLAPQCTVTF
860 870
LQSEDGSGKG AALVTAVACR LTQMAHV
Length:877
Mass (Da):95,424
Last modified:April 5, 2011 - v1
Checksum:i85B718A47ACA24CE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC154610 Genomic DNA. No translation available.
RefSeqiNP_001193320.1. NM_001206391.1.
UniGeneiMm.267479.

Genome annotation databases

EnsembliENSMUST00000123097; ENSMUSP00000116717; ENSMUSG00000025877.
GeneIDi212032.
KEGGimmu:212032.
UCSCiuc007qps.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC154610 Genomic DNA. No translation available.
RefSeqi NP_001193320.1. NM_001206391.1.
UniGenei Mm.267479.

3D structure databases

ProteinModelPortali E9Q8S8.
SMRi E9Q8S8. Positions 35-873.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000123097 ; ENSMUSP00000116717 ; ENSMUSG00000025877 .
GeneIDi 212032.
KEGGi mmu:212032.
UCSCi uc007qps.2. mouse.

Organism-specific databases

CTDi 3101.
MGIi MGI:2670962. Hk3.

Phylogenomic databases

GeneTreei ENSGT00390000017159.
KOi K00844.

Miscellaneous databases

NextBioi 373427.
SOURCEi Search...

Gene expression databases

Bgeei E9Q8S8.
ExpressionAtlasi E9Q8S8. baseline and differential.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 1 hit.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
PROSITEi PS00378. HEXOKINASES. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q8S8_MOUSE
AccessioniPrimary (citable) accession number: E9Q8S8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 29, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3