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E9Q8S8

- E9Q8S8_MOUSE

UniProt

E9Q8S8 - E9Q8S8_MOUSE

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Protein
Submitted name:

Hexokinase-3

Gene
Hk3
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. fructokinase activity Source: RefGenome
  3. glucokinase activity Source: RefGenome
  4. mannokinase activity Source: RefGenome

GO - Biological processi

  1. carbohydrate phosphorylation Source: GOC
  2. cellular glucose homeostasis Source: RefGenome
  3. glucose 6-phosphate metabolic process Source: GOC
  4. glycolytic process Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotations, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase-3Imported
Gene namesi
Name:Hk3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 13

Organism-specific databases

MGIiMGI:2670962. Hk3.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: RefGenome
  2. mitochondrion Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiE9Q8S8.
BgeeiE9Q8S8.

Structurei

3D structure databases

ProteinModelPortaliE9Q8S8.
SMRiE9Q8S8. Positions 35-873.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000017159.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q8S8-1 [UniParc]FASTAAdd to Basket

« Hide

MATIGPSGLH PGERASVCPH EGVPRPSGSL ELECLQQFKV TRTQLQQIQA    50
SLLCSMEQAL KGQDSPAPSV RMLPTYVRST PHGTEQGDFL VLELGATGAS 100
LRVLWVTLTG TKECRVEPRS REFVIPQEVI LGAGQQLFDF AARCLSEFLD 150
AYPVENQGLK LGFNFSFPCH QTGLDRSTLI SWTKGFRCSG VEGQDVVQLL 200
RDAIQRQGTY RIDVVAMVND TVGTMMGCEL GTRPCEVGLI VDTGTNACYM 250
EEARHVAALD EDRGRTCVSI EWGSFYDEDA LGPVLTTFDS ALDRESLTPG 300
AQRFEKMIGG LYLGELVRLV LVHLTQHGVL FDGCASPALL SQGCILLDHV 350
AEMEDTATGT ARVHTILQDL GLSPRASDAE LVQYVCVAVC TRAAQLCAAA 400
LAAVLSRLQH SREQQTLQVA VATGGRVFER HPRRILEETL APFQLTLEQM 450
TVVQAQMREA MIRGLQGEAS SLRMLPTYVR ATPDGSERGD FLALDLGGTN 500
FRVLLVRVAE GSVQIINQVY SIPECRAQGS GQKLFDHIVD CIVDFQKRQG 550
LSGQSLPLGF TFSFPCKQLG LDQGILLNWT KGFNASGCEG QDVVYLLREA 600
IRRRQAVELN VVAIVNDTVG TMMSCGYDDP RCEMGLIVGT GTNACYMEEL 650
RNVASVPGDS GLMCINMEWG AFGDDGSLGT LSTRFDTSVD QASINPGKQR 700
FEKMISGMYL GEIVRHILLH LTNLGVLFRG QKTQCLQARD IFKTKFLSEI 750
ESDSLALRQV RAILEDLGLT LTSDDALMVL EVCQAVSRRA AQLCGAGVAA 800
VVEKIRENRG LQELTVSVGV DGTLYKLHPH FSKLVSATVR KLAPQCTVTF 850
LQSEDGSGKG AALVTAVACR LTQMAHV 877
Length:877
Mass (Da):95,424
Last modified:April 5, 2011 - v1
Checksum:i85B718A47ACA24CE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC154610 Genomic DNA. No translation available.
RefSeqiNP_001193320.1. NM_001206391.1.
UniGeneiMm.267479.

Genome annotation databases

EnsembliENSMUST00000123097; ENSMUSP00000116717; ENSMUSG00000025877.
GeneIDi212032.
KEGGimmu:212032.
UCSCiuc007qps.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC154610 Genomic DNA. No translation available.
RefSeqi NP_001193320.1. NM_001206391.1.
UniGenei Mm.267479.

3D structure databases

ProteinModelPortali E9Q8S8.
SMRi E9Q8S8. Positions 35-873.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000123097 ; ENSMUSP00000116717 ; ENSMUSG00000025877 .
GeneIDi 212032.
KEGGi mmu:212032.
UCSCi uc007qps.2. mouse.

Organism-specific databases

CTDi 3101.
MGIi MGI:2670962. Hk3.

Phylogenomic databases

GeneTreei ENSGT00390000017159.
KOi K00844.

Miscellaneous databases

NextBioi 373427.
SOURCEi Search...

Gene expression databases

ArrayExpressi E9Q8S8.
Bgeei E9Q8S8.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 1 hit.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
PROSITEi PS00378. HEXOKINASES. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q8S8_MOUSE
AccessioniPrimary (citable) accession number: E9Q8S8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 9, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi