ID   E9Q8A6_MOUSE            Unreviewed;       129 AA.
AC   E9Q8A6;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 8.
DT   27-MAR-2024, entry version 89.
DE   SubName: Full=Nuclear receptor subfamily 3, group C, member 1 {ECO:0000313|Ensembl:ENSMUSP00000119630.2};
DE   Flags: Fragment;
GN   Name=Nr3c1 {ECO:0000313|Ensembl:ENSMUSP00000119630.2,
GN   ECO:0000313|MGI:MGI:95824};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000119630.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000119630.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000119630.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0007829|PubMed:21183079}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
RN   [3] {ECO:0007829|PubMed:24129315}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=24129315;
RA   Guo A., Gu H., Zhou J., Mulhern D., Wang Y., Lee K.A., Yang V., Aguiar M.,
RA   Kornhauser J., Jia X., Ren J., Beausoleil S.A., Silva J.C., Vemulapalli V.,
RA   Bedford M.T., Comb M.J.;
RT   "Immunoaffinity enrichment and mass spectrometry analysis of protein
RT   methylation.";
RL   Mol. Cell. Proteomics 13:372-387(2014).
RN   [4] {ECO:0000313|Ensembl:ENSMUSP00000119630.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000119630.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; E9Q8A6; -.
DR   jPOST; E9Q8A6; -.
DR   PeptideAtlas; E9Q8A6; -.
DR   ProteomicsDB; 302421; -.
DR   Antibodypedia; 1329; 1586 antibodies from 44 providers.
DR   Ensembl; ENSMUST00000124115.2; ENSMUSP00000119630.2; ENSMUSG00000024431.16.
DR   AGR; MGI:95824; -.
DR   MGI; MGI:95824; Nr3c1.
DR   VEuPathDB; HostDB:ENSMUSG00000024431; -.
DR   GeneTree; ENSGT00940000156385; -.
DR   HOGENOM; CLU_150385_0_0_1; -.
DR   OMA; GLYMGDT; -.
DR   ChiTaRS; Nr3c1; mouse.
DR   Proteomes; UP000000589; Chromosome 18.
DR   Bgee; ENSMUSG00000024431; Expressed in median eminence of neurohypophysis and 273 other cell types or tissues.
DR   ExpressionAtlas; E9Q8A6; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004883; F:nuclear glucocorticoid receptor activity; IEA:InterPro.
DR   GO; GO:0005496; F:steroid binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   InterPro; IPR001409; Glcrtcd_rcpt.
DR   Pfam; PF02155; GCR; 1.
DR   PRINTS; PR00528; GLCORTICOIDR.
PE   1: Evidence at protein level;
KW   Proteomics identification {ECO:0007829|EPD:E9Q8A6,
KW   ECO:0007829|MaxQB:E9Q8A6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          66..104
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..98
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         129
FT                   /evidence="ECO:0000313|Ensembl:ENSMUSP00000119630.2"
SQ   SEQUENCE   129 AA;  13796 MW;  C327A9A19DA3C9C3 CRC64;
     MDSKESLAPP GRDEVPSSLL GRGRGSVMDL YKTLRGGATV KVSASSPSVA AASQADSKQQ
     RILLDFSKGS ASNAQQQQQQ QQQQQQQQQQ QPQPDLSKAV SLSMGLYMGE TETKVMGNDL
     GYPQQGQLG
//