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E9Q8A6

- E9Q8A6_MOUSE

UniProt

E9Q8A6 - E9Q8A6_MOUSE

Protein
Submitted name:

Glucocorticoid receptor

Gene

Nr3c1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. DNA binding Source: MGI
    2. glucocorticoid receptor activity Source: MGI
    3. protein binding Source: MGI
    4. protein dimerization activity Source: MGI
    5. sequence-specific DNA binding Source: MGI
    6. steroid binding Source: InterPro

    GO - Biological processi

    1. adrenal gland development Source: MGI
    2. glucocorticoid metabolic process Source: MGI
    3. glucocorticoid receptor signaling pathway Source: MGI
    4. mammary gland duct morphogenesis Source: MGI
    5. maternal behavior Source: MGI
    6. negative regulation of glucocorticoid mediated signaling pathway Source: MGI
    7. positive regulation of neuron apoptotic process Source: MGI
    8. regulation of glucocorticoid biosynthetic process Source: MGI
    9. regulation of gluconeogenesis Source: MGI
    10. regulation of transcription, DNA-templated Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Glucocorticoid receptorImported
    Gene namesi
    Name:Nr3c1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 18

    Organism-specific databases

    MGIiMGI:95824. Nr3c1.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: MGI
    2. cytosol Source: MGI
    3. intracellular Source: MGI
    4. membrane Source: MGI
    5. nucleus Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiE9Q8A6.
    BgeeiE9Q8A6.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00730000110451.

    Family and domain databases

    InterProiIPR001409. Glcrtcd_rcpt.
    [Graphical view]
    PfamiPF02155. GCR. 2 hits.
    [Graphical view]
    PRINTSiPR00528. GLCORTICOIDR.

    Sequencei

    Sequence statusi: Fragment.

    E9Q8A6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDSKESLAPP GRDEVPSSLL GRGRGSVMDL YKTLRGGATV KVSASSPSVA    50
    AASQADSKQQ RILLDFSKGS ASNAQQQQQQ QQQQQQQQQQ QPQPDLSKAV 100
    SLSMGLYMGE TETKVMGNDL GYPQQGQLG 129
    Length:129
    Mass (Da):13,796
    Last modified:May 14, 2014 - v2
    Checksum:iC327A9A19DA3C9C3
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei129 – 1291Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC007995 Genomic DNA. No translation available.
    AC124417 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000124115; ENSMUSP00000119630; ENSMUSG00000024431.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC007995 Genomic DNA. No translation available.
    AC124417 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000124115 ; ENSMUSP00000119630 ; ENSMUSG00000024431 .

    Organism-specific databases

    MGIi MGI:95824. Nr3c1.

    Phylogenomic databases

    GeneTreei ENSGT00730000110451.

    Miscellaneous databases

    ChiTaRSi NR3C1. mouse.
    NextBioi 35555599.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9Q8A6.
    Bgeei E9Q8A6.

    Family and domain databases

    InterProi IPR001409. Glcrtcd_rcpt.
    [Graphical view ]
    Pfami PF02155. GCR. 2 hits.
    [Graphical view ]
    PRINTSi PR00528. GLCORTICOIDR.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9Q8A6_MOUSE
    AccessioniPrimary (citable) accession number: E9Q8A6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: May 14, 2014
    Last modified: October 1, 2014
    This is version 30 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3