E9Q8A6 (E9Q8A6_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glucocorticoid receptor Ensembl ENSMUSP00000119630

Gene names

Name:

Nr3c1 Ensembl ENSMUSP00000119630 MGI 95824

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000119630

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	130 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000119630

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	adrenal gland development Inferred from mutant phenotype PubMed 7628695. Source: MGI glucocorticoid metabolic process Inferred from mutant phenotype PubMed 10509797. Source: MGI glucocorticoid receptor signaling pathway Inferred from direct assay PubMed 15199138. Source: MGI mammary gland duct morphogenesis Inferred from mutant phenotype PubMed 12198239. Source: MGI positive regulation of neuron apoptotic process Inferred from genetic interaction PubMed 10744634. Source: MGI regulation of glucocorticoid biosynthetic process Inferred from mutant phenotype PubMed 7628695. Source: MGI regulation of gluconeogenesis Inferred from mutant phenotype PubMed 7628695. Source: MGI regulation of transcription, DNA-templated Inferred from direct assay PubMed 10224232. Source: MGI
Cellular_component	cytosol Inferred from direct assay PubMed 7914432. Source: MGI intracellular Inferred from direct assay PubMed 9237103. Source: MGI membrane Inferred from direct assay PubMed 9237103. Source: MGI nucleus Inferred from direct assay PubMed 11555636PubMed 15870285PubMed 7914432. Source: MGI
Molecular_function	DNA binding Inferred from direct assay PubMed 15870285. Source: MGI glucocorticoid receptor activity Inferred from direct assay PubMed 15199138PubMed 7914432PubMed 9237103. Source: MGI protein dimerization activity Inferred from direct assay PubMed 7883868. Source: MGI sequence-specific DNA binding Inferred from direct assay PubMed 7883868. Source: MGI steroid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	130	1	Ensembl ENSMUSP00000119630

Sequences

	Sequence		Length	Mass (Da)
	E9Q8A6 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: D15327A9A19DA3C9	FASTA	130	13,909
	10 20 30 40 50 60 MDSKESLAPP GRDEVPSSLL GRGRGSVMDL YKTLRGGATV KVSASSPSVA AASQADSKQQ 70 80 90 100 110 120 RILLDFSKGS ASNAQQQQQQ QQQQQQQQQQ QPQPDLSKAV SLSMGLYMGE TETKVMGNDL 130 GYPQQGQLGL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000119630.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000119630.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC007995 Genomic DNA. No translation available. AC124417 Genomic DNA. No translation available.
3D structure databases
ModBase	Search...
MobiDB	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000124115; ENSMUSP00000119630; ENSMUSG00000024431.
Organism-specific databases
MGI	MGI:95824. Nr3c1.
Phylogenomic databases
GeneTree	ENSGT00730000110451.
Gene expression databases
ArrayExpress	E9Q8A6.
Bgee	E9Q8A6.
Family and domain databases
InterPro	IPR001409. Glcrtcd_rcpt. [Graphical view]
Pfam	PF02155. GCR. 1 hit. [Graphical view]
PRINTS	PR00528. GLCORTICOIDR.
ProtoNet	Search...
Other
ChiTaRS	NR3C1. mouse.
NextBio	35555599.
SOURCE	Search...

Entry information

Entry name

E9Q8A6_MOUSE

Accession

Primary (citable) accession number: E9Q8A6

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	April 16, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)