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Protein
Submitted name:

Protein Nav2

Gene

Nav2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • heparin binding Source: MGI

GO - Biological processi

  • glossopharyngeal nerve development Source: MGI
  • locomotory behavior Source: MGI
  • optic nerve development Source: MGI
  • regulation of systemic arterial blood pressure by baroreceptor feedback Source: MGI
  • sensory perception of smell Source: MGI
  • sensory perception of sound Source: MGI
  • vagus nerve development Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Nav2Imported
Gene namesi
Name:Nav2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:2183691. Nav2.

Subcellular locationi

GO - Cellular componenti

  • interstitial matrix Source: MGI
  • nucleoplasm Source: MGI
  • proteinaceous extracellular matrix Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiE9Q842.
PaxDbiE9Q842.
PeptideAtlasiE9Q842.

Expressioni

Gene expression databases

BgeeiENSMUSG00000052512.
ExpressionAtlasiE9Q842. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000067448.

Structurei

3D structure databases

ProteinModelPortaliE9Q842.
SMRiE9Q842. Positions 86-193.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini82 – 189108Actin-bindingInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili487 – 51428Sequence analysisAdd
BLAST
Coiled coili1630 – 165728Sequence analysisAdd
BLAST
Coiled coili1679 – 171335Sequence analysisAdd
BLAST
Coiled coili1841 – 186828Sequence analysisAdd
BLAST
Coiled coili1876 – 190328Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IGVF. Eukaryota.
ENOG410XRG8. LUCA.
GeneTreeiENSGT00530000063334.
InParanoidiE9Q842.
OMAiERNSLWS.
OrthoDBiEOG091G03NO.
TreeFamiTF329881.

Family and domain databases

Gene3Di1.10.418.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR001715. CH-domain.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00307. CH. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00033. CH. 1 hit.
[Graphical view]
SUPFAMiSSF47576. SSF47576. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS50021. CH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q842-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPAILVASKM KSGLPKPVHS AAPILHVPPA RTGPQPCYLK LGSKVEVSKT
60 70 80 90 100
AYTSQIPLKS QGLQEPTGEG LPLLKSSSLE NGFDTQIYTD WANHYLAKSG
110 120 130 140 150
HKRLIKDLQQ DVTDGVLLAQ IIQVVANDKI EDINGCPKNR SQMIENIDAC
160 170 180 190 200
LNFLAAKGIN TQGLSAEEIR NGNLKAILGL FFSLSRYKQQ QQQQQQQPEK
210 220 230 240 250
QPLSSSPLPP AGSQVAGAPS QCQAGTPQHQ GLATPQAPCQ LLQPVSHQQG
260 270 280 290 300
KTQVEMQSRL PGPTARVAAA GSEAKTRGGS AAANNRRSQS FNNYDKSKPV
310 320 330 340 350
TSPPPPAPPS NHEKEPLASS ASSHPGMSEN VPAPLENSPS VPVNCSSSAI
360 370 380 390 400
PQPSMTSKPW RSKSLSVKHT ATSAMLSVKP AGPEAPRPTP EAMKPAPNNQ
410 420 430 440 450
KSMLEKLKLF NSKGGSKAGE GSASRDTSCE RLEILPSFEE TEELEATANR
460 470 480 490 500
ALSTVGPASS SPKIALKGIA QRTFSRALTN KKSSPKGNEK EKEKQQREKE
510 520 530 540 550
KEKEKEKGKD LTKRVSVTDR PDLKEETKAD LSGVAVTEMP KKSSKIASFI
560 570 580 590 600
PKGGKLNSTK KEATAPSHSG IPKPGMKNVS AKSPSAPIPP KEGERSRGKL
610 620 630 640 650
SSGLPPQKAQ LDSRHSSSSS SLASSEGKGP GGTSLNPSIS SQTVSGSVGT
660 670 680 690 700
TQTTGSNTVS VQLPQPQQQY NHPNTATVAP FLYRSQTDTE GNVTAESSSA
710 720 730 740 750
GVSMEPSHYT KSGQPALEEL TEDPEARRLR TVKNIADLRQ NLEETMSSLR
760 770 780 790 800
GTQVTHSTLE TTFDTNVTTE ISGRSILSLT GRPTPLSWRL GQSSPRLQAG
810 820 830 840 850
DAPSMGNGYP PRANASRFIS AEAGRYVYSA PLRRQLASRG SSICHVDVSD
860 870 880 890 900
KADDDVDLEG ISMDAPGYMS DGDVLSKNIR SDDITSGYMT DGGLGLYTRR
910 920 930 940 950
LNRLPDGMAV VRETLQRNTS LGLGDADSWD DSSSVSSGIS DTIDNLSTDD
960 970 980 990 1000
INTSSSISSY ANTPASSRRN LDVQTDAEKH SQVERNSLWS GDDIKKSDGG
1010 1020 1030 1040 1050
SDSGVKMEPG SKWRRNPSDM SDESDKSVSG KKNPVLSQTG SWRRGMTAEV
1060 1070 1080 1090 1100
GITMPRTKPS APTGTLKTPG TGKTDDAKVS EKGRLSPKAS QVKRSPSDAG
1110 1120 1130 1140 1150
RSSGDESKKT LPSSSRTPTV NANSFGFKKQ SGSAAGLAMI TASGATVTSR
1160 1170 1180 1190 1200
SATLGKIPKS SALVGRPTGR KTSMDGAPNQ DDGYLSLSSR TNLQYRSLPR
1210 1220 1230 1240 1250
PSKSNSRNGA GNRCSTSSID SNMSSKSAGL PVPKLREPSK ASLGSSLPGL
1260 1270 1280 1290 1300
VNQTDKEKGI SSDSESVASC NSVKVNPATQ PVSSSAQATL QPGTKYADVA
1310 1320 1330 1340 1350
SPTLRRLFGG KPTKPIATAE TMKSAVVISN PHATLTQQGN LESPSGSGVL
1360 1370 1380 1390 1400
SSGSSSPLYS KNVDLNQSPL ASSPSSAHSG PSNSLTWGTS SSAVSKDGLG
1410 1420 1430 1440 1450
FQSVSSLHTS CESIDISLGS GGGLSHNSSP GPVASTKEDS LMPFVRTSSV
1460 1470 1480 1490 1500
KTTLSESPLS SPAASPKFCR STLPRKQDSD PHLDRNTLPK KGLRYTPTSQ
1510 1520 1530 1540 1550
LRTQEDAKEW FRSHSAGGLQ DTATNSPFSS GSSVTSPSGT RFNFSQLASP
1560 1570 1580 1590 1600
TAVTQMSLSN PTMLRTHSLS NADGQYDPYT DSRFRNSSMS LDEKSRTMSR
1610 1620 1630 1640 1650
SGSFRDGFEE VHGSSLSLVS STSSIYSTPE EKCQSEIRKL RRELDASQEK
1660 1670 1680 1690 1700
VSALTTQLTA NAHLVAAFEQ SLGNMTIRLQ SLTMTAEQKD SELNELRKTI
1710 1720 1730 1740 1750
ELLKKQNAAA QAAINGVINT PELNCKGNGS AQATDLRIRR QHSSDSVSSI
1760 1770 1780 1790 1800
NSATSHSSVG SNIESDSKKK KRKNWVSQLR SSFKQAFGKK KSPKSASSHS
1810 1820 1830 1840 1850
DIEEMTDSSL PSSPKLPHNG STGSTPLLRN AHSNSLISEC MDSEAETVMQ
1860 1870 1880 1890 1900
LRNELRDKEM KLTDIRLEAL SSAHQLDQLR EAMNRMQSEI EKLKAENDRL
1910 1920 1930 1940 1950
KSESQGSGCS RAPSQVSISA SPRQSLGLSQ HSLNLTESTS LDMLLDDTGE
1960 1970 1980 1990 2000
CSARKEGGRH VKIVVSFQEA MKWKEDSRPH LFLIGCIGVS GKTKWDVLDG
2010 2020 2030 2040 2050
VVRRLFKEYI VHVDPVSQLG LSSDSVLGYS IGEIKRSNAS ETPELLPCGY
2060 2070 2080 2090 2100
LVGENTTILV TVKGLTENSL DSLVFESLIP KPILQRYVSL LTEHRRIILS
2110 2120 2130 2140 2150
GPSGTGKTYL ANRLSEYVVL REGRELTDGV IATFNVDHKS SKELRQYLSN
2160 2170 2180 2190 2200
LADQCNSENN AVDMPLVIIL DNLHHVSSLG EIFNGLLNCK YHKCPYIIGT
2210 2220 2230 2240 2250
MNQATSSTPN LQLHHNFRWV LCANHTEPVK GFLGRFLRRK LMETEISGRV
2260 2270 2280 2290 2300
RNAELVKIIN WIPKVWHHLN RFLEAHSSSD VTIGPRLFLS CPIDVDGSRV
2310 2320 2330 2340 2350
WFTDLWNYSI IPYLLEAVRE GLQLYGRRAP WEDPAKWVMD TYPWAASPQQ
2360 2370 2380 2390 2400
HEWPPLLQLR PEDVGFDGYS LPREGSTSKQ VPPSDTEGDP LMNMLMRLQE
2410 2420 2430
AANYSSPQSY DSDSNSNSHH DDILDSSLES TL
Length:2,432
Mass (Da):261,634
Last modified:April 5, 2011 - v1
Checksum:iD19A9726E40519BD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC107862 Genomic DNA. No translation available.
AC114612 Genomic DNA. No translation available.
AC119804 Genomic DNA. No translation available.
AC119848 Genomic DNA. No translation available.
AC120854 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000064395; ENSMUSP00000067448; ENSMUSG00000052512.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC107862 Genomic DNA. No translation available.
AC114612 Genomic DNA. No translation available.
AC119804 Genomic DNA. No translation available.
AC119848 Genomic DNA. No translation available.
AC120854 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE9Q842.
SMRiE9Q842. Positions 86-193.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000067448.

Proteomic databases

MaxQBiE9Q842.
PaxDbiE9Q842.
PeptideAtlasiE9Q842.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000064395; ENSMUSP00000067448; ENSMUSG00000052512.

Organism-specific databases

MGIiMGI:2183691. Nav2.

Phylogenomic databases

eggNOGiENOG410IGVF. Eukaryota.
ENOG410XRG8. LUCA.
GeneTreeiENSGT00530000063334.
InParanoidiE9Q842.
OMAiERNSLWS.
OrthoDBiEOG091G03NO.
TreeFamiTF329881.

Miscellaneous databases

ChiTaRSiNav2. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000052512.
ExpressionAtlasiE9Q842. baseline and differential.

Family and domain databases

Gene3Di1.10.418.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR001715. CH-domain.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00307. CH. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00033. CH. 1 hit.
[Graphical view]
SUPFAMiSSF47576. SSF47576. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiPS50021. CH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q842_MOUSE
AccessioniPrimary (citable) accession number: E9Q842
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 7, 2016
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.