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Protein
Submitted name:

Ataxin-3

Gene

Atxn3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei14PROSITE-ProRule annotation1
Active sitei119PROSITE-ProRule annotation1
Active sitei134PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolasePROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Ataxin-3Imported
Gene namesi
Name:Atxn3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:1099442 Atxn3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiE9Q717
PeptideAtlasiE9Q717

Expressioni

Gene expression databases

BgeeiENSMUSG00000021189
ExpressionAtlasiE9Q717 baseline and differential
GenevisibleiE9Q717 MM

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliE9Q717
SMRiE9Q717
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 180JosephinInterPro annotationAdd BLAST180

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili235 – 255Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2935 Eukaryota
ENOG4111G4B LUCA
GeneTreeiENSGT00390000001830

Family and domain databases

InterProiView protein in InterPro
IPR033865 Ataxin-3
IPR006155 Josephin
IPR003903 UIM_dom
PANTHERiPTHR14159 PTHR14159, 1 hit
PfamiView protein in Pfam
PF02099 Josephin, 1 hit
PF02809 UIM, 2 hits
SMARTiView protein in SMART
SM01246 Josephin, 1 hit
SM00726 UIM, 2 hits
PROSITEiView protein in PROSITE
PS50957 JOSEPHIN, 1 hit
PS50330 UIM, 2 hits

Sequencei

Sequence statusi: Complete.

E9Q717-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESIFHEKQE GSLCAQHCLN NLLQGEYFSP VELSSIAHQL DEEERLRMAE
60 70 80 90 100
GGVTSEDYRT FLQQPSGNMD DSGFFSIQVI SNALKVWGLE LILFNSPEYQ
110 120 130 140 150
RLRIDPINER SFICNYKEHW FTVRKLGKQW FNLNSLLTGP ELISDTYLAL
160 170 180 190 200
FLAQLQQEGY SIFVVKGDLP DCEADQLLQM IKVQQMHRPK LIGEELAHLK
210 220 230 240 250
EQSALKADLE RVLEAADGSG IFDEDEDDLQ RALAISRQEI DMEDEEADLR
260 270 280 290
RAIQLSMQGS SRSMCENSPQ TSSPDLSSEE LRRRREAYFE K
Length:291
Mass (Da):33,435
Last modified:April 5, 2011 - v1
Checksum:i3F3DF245ABE63527
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121965 Genomic DNA No translation available.
RefSeqiNP_001161386.1, NM_001167914.1
UniGeneiMm.271914

Genome annotation databases

EnsembliENSMUST00000161011; ENSMUSP00000125378; ENSMUSG00000021189
GeneIDi110616

Similar proteinsi

Entry informationi

Entry nameiE9Q717_MOUSE
AccessioniPrimary (citable) accession number: E9Q717
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: March 28, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported