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Protein
Submitted name:

Adenylate cyclase type 9

Gene

Adcy9

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotation
LigandNucleotide-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate cyclase type 9Imported
Gene namesi
Name:Adcy9Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:108450 Adcy9

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei5 – 24HelicalSequence analysisAdd BLAST20
Transmembranei44 – 63HelicalSequence analysisAdd BLAST20
Transmembranei551 – 572HelicalSequence analysisAdd BLAST22
Transmembranei584 – 608HelicalSequence analysisAdd BLAST25
Transmembranei629 – 647HelicalSequence analysisAdd BLAST19
Transmembranei653 – 673HelicalSequence analysisAdd BLAST21
Transmembranei740 – 759HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

MaxQBiE9Q706
PeptideAtlasiE9Q706
PRIDEiE9Q706

Expressioni

Gene expression databases

BgeeiENSMUSG00000005580
ExpressionAtlasiE9Q706 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9Q706
SMRiE9Q706
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini157 – 284Guanylate cyclaseInterPro annotationAdd BLAST128
Domaini821 – 961Guanylate cyclaseInterPro annotationAdd BLAST141

Sequence similaritiesi

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3618 Eukaryota
COG2114 LUCA
GeneTreeiENSGT00760000119042

Family and domain databases

Gene3Di3.30.70.1230, 2 hits
InterProiView protein in InterPro
IPR001054 A/G_cyclase
IPR018297 A/G_cyclase_CS
IPR029787 Nucleotide_cyclase
PfamiView protein in Pfam
PF00211 Guanylate_cyc, 2 hits
SMARTiView protein in SMART
SM00044 CYCc, 2 hits
SUPFAMiSSF55073 SSF55073, 2 hits
PROSITEiView protein in PROSITE
PS00452 GUANYLATE_CYCLASE_1, 2 hits
PS50125 GUANYLATE_CYCLASE_2, 2 hits

Sequencei

Sequence statusi: Complete.

E9Q706-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLPLYLSLF LGVVYSVLFE TFGYHFRNED CYPSPGPGAL HWELLSRALL
60 70 80 90 100
HVCIHAIGIH LFVMSQVRSR STFLKVGQSI MHGKDLEVEK ALKERMIHSV
110 120 130 140 150
MPRIIADDLM KQGDEESENS VKRHATSSPK NRKKKSSIQK APIAFRPFKM
160 170 180 190 200
QQIEEVSILF ADIVGFTKMS ANKSAHALVG LLNDLFGRFD RLCEQTKCEK
210 220 230 240 250
ISTLGDCYYC VAGCPEPRAD HAYCCIEMGL GMIKAIEQFC QEKKEMVNMR
260 270 280 290 300
VGVHTGTVLC GILGMRRFKF DVWSNDVNLA NLMEQLGVAG KVHISEATAK
310 320 330 340 350
YLDDRYEMED GRVIERLGQS VVADQLKGLK TYLISGQRAK ESHCSCAEAL
360 370 380 390 400
LSGFEVIDDS RESSGPRGQG TASPGSVSDL AQTVKTFDNL KTCPSCGITF
410 420 430 440 450
APKSEAGAEG GTVQNGCQDE PKTSTKASGG PNSKTQNGLL SPPAEEKLTN
460 470 480 490 500
SQTSLCEILQ EKGRWAGVSL DQSALLPLRF KNIREKTDAH FVDVIKEDSL
510 520 530 540 550
MKDYFFKPPI NQFSLNFLDQ ELERSYRTSY QEEVIKNSPV KTFASATFSS
560 570 580 590 600
LLDVFLSTTV FLILSITCFL KYGATATPPP PAALAVFGAD LLLEVLSLIV
610 620 630 640 650
SIRMVFFLED VMTCTKWLLE WIAGWLPRHC IGAILVSLPA LAVYSHITSE
660 670 680 690 700
FETNIHVTMF TGSAVLVAVV HYCNFCQLSS WMRSSLATIV GAGLLLLLHI
710 720 730 740 750
SLCQDSSIVM SPLDSAQNFS AQRNPCNSSV LQDGRRPASL IGKELILTFF
760 770 780 790 800
LLLLLVWFLN REFEVSYRLH YHGDVEADLH RTKIQSMRDQ ADWLLRNIIP
810 820 830 840 850
YHVAEQLKVS QTYSKNHDSG GVIFASIVNF SEFYEENYEG GKECYRVLNE
860 870 880 890 900
LIGDFDELLS KPDYNSIEKI KTIGATYMAA SGLNTAQCQE GGHPQEHLRI
910 920 930 940 950
LFEFAKEMMR VVDDFNNNML WFNFKLRVGF NHGPLTAGVI GTTKLLYDIW
960 970 980 990 1000
GDTVNIASRM DTTGVECRIQ VSEESYRVLS KMGYDFDYRG TVNVKGKGQM
1010 1020 1030 1040 1050
KTYLYPKCTD NGVVPQHQLS ISPDIRVQVD GSIGRSPTDE IANLVPSVQY
1060 1070 1080 1090 1100
SDKASLGSDD STQAKEARLS SKRSWREPVK AEERFPFGKA IEKDSCEDIG
1110
VEEASELSKL NVSKSV
Length:1,116
Mass (Da):124,388
Last modified:April 5, 2011 - v1
Checksum:i1C4E4A174C99CFAA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087799 Genomic DNA No translation available.
AC132575 Genomic DNA No translation available.
RefSeqiNP_001278839.1, NM_001291910.1
UniGeneiMm.439750
Mm.482493

Genome annotation databases

EnsembliENSMUST00000120080; ENSMUSP00000113421; ENSMUSG00000005580
GeneIDi11515

Similar proteinsi

Entry informationi

Entry nameiE9Q706_MOUSE
AccessioniPrimary (citable) accession number: E9Q706
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: March 28, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health