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E9Q706

- E9Q706_MOUSE

UniProt

E9Q706 - E9Q706_MOUSE

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Protein
Submitted name:

Adenylate cyclase type 9

Gene

Adcy9

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. adenylate cyclase activity Source: MGI
  2. nucleotide binding Source: UniProtKB-KW

GO - Biological processi

  1. activation of adenylate cyclase activity Source: MGI
  2. cAMP biosynthetic process Source: MGI
  3. intracellular signal transduction Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Ligandi

Nucleotide-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate cyclase type 9Imported
Gene namesi
Name:Adcy9Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 16

Organism-specific databases

MGIiMGI:108450. Adcy9.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiE9Q706.
ExpressionAtlasiE9Q706. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9Q706.
SMRiE9Q706. Positions 143-316, 813-1004.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000119042.
KOiK08049.

Family and domain databases

Gene3Di3.30.70.1230. 2 hits.
InterProiIPR001054. A/G_cyclase.
IPR018297. A/G_cyclase_CS.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 2 hits.
[Graphical view]
SMARTiSM00044. CYCc. 2 hits.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 2 hits.
PROSITEiPS00452. GUANYLATE_CYCLASE_1. 2 hits.
PS50125. GUANYLATE_CYCLASE_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q706-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQLPLYLSLF LGVVYSVLFE TFGYHFRNED CYPSPGPGAL HWELLSRALL
60 70 80 90 100
HVCIHAIGIH LFVMSQVRSR STFLKVGQSI MHGKDLEVEK ALKERMIHSV
110 120 130 140 150
MPRIIADDLM KQGDEESENS VKRHATSSPK NRKKKSSIQK APIAFRPFKM
160 170 180 190 200
QQIEEVSILF ADIVGFTKMS ANKSAHALVG LLNDLFGRFD RLCEQTKCEK
210 220 230 240 250
ISTLGDCYYC VAGCPEPRAD HAYCCIEMGL GMIKAIEQFC QEKKEMVNMR
260 270 280 290 300
VGVHTGTVLC GILGMRRFKF DVWSNDVNLA NLMEQLGVAG KVHISEATAK
310 320 330 340 350
YLDDRYEMED GRVIERLGQS VVADQLKGLK TYLISGQRAK ESHCSCAEAL
360 370 380 390 400
LSGFEVIDDS RESSGPRGQG TASPGSVSDL AQTVKTFDNL KTCPSCGITF
410 420 430 440 450
APKSEAGAEG GTVQNGCQDE PKTSTKASGG PNSKTQNGLL SPPAEEKLTN
460 470 480 490 500
SQTSLCEILQ EKGRWAGVSL DQSALLPLRF KNIREKTDAH FVDVIKEDSL
510 520 530 540 550
MKDYFFKPPI NQFSLNFLDQ ELERSYRTSY QEEVIKNSPV KTFASATFSS
560 570 580 590 600
LLDVFLSTTV FLILSITCFL KYGATATPPP PAALAVFGAD LLLEVLSLIV
610 620 630 640 650
SIRMVFFLED VMTCTKWLLE WIAGWLPRHC IGAILVSLPA LAVYSHITSE
660 670 680 690 700
FETNIHVTMF TGSAVLVAVV HYCNFCQLSS WMRSSLATIV GAGLLLLLHI
710 720 730 740 750
SLCQDSSIVM SPLDSAQNFS AQRNPCNSSV LQDGRRPASL IGKELILTFF
760 770 780 790 800
LLLLLVWFLN REFEVSYRLH YHGDVEADLH RTKIQSMRDQ ADWLLRNIIP
810 820 830 840 850
YHVAEQLKVS QTYSKNHDSG GVIFASIVNF SEFYEENYEG GKECYRVLNE
860 870 880 890 900
LIGDFDELLS KPDYNSIEKI KTIGATYMAA SGLNTAQCQE GGHPQEHLRI
910 920 930 940 950
LFEFAKEMMR VVDDFNNNML WFNFKLRVGF NHGPLTAGVI GTTKLLYDIW
960 970 980 990 1000
GDTVNIASRM DTTGVECRIQ VSEESYRVLS KMGYDFDYRG TVNVKGKGQM
1010 1020 1030 1040 1050
KTYLYPKCTD NGVVPQHQLS ISPDIRVQVD GSIGRSPTDE IANLVPSVQY
1060 1070 1080 1090 1100
SDKASLGSDD STQAKEARLS SKRSWREPVK AEERFPFGKA IEKDSCEDIG
1110
VEEASELSKL NVSKSV
Length:1,116
Mass (Da):124,388
Last modified:April 5, 2011 - v1
Checksum:i1C4E4A174C99CFAA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087799 Genomic DNA. No translation available.
AC132575 Genomic DNA. No translation available.
RefSeqiNP_001278839.1. NM_001291910.1.
UniGeneiMm.439750.
Mm.482493.

Genome annotation databases

EnsembliENSMUST00000120080; ENSMUSP00000113421; ENSMUSG00000005580.
GeneIDi11515.
KEGGimmu:11515.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087799 Genomic DNA. No translation available.
AC132575 Genomic DNA. No translation available.
RefSeqi NP_001278839.1. NM_001291910.1.
UniGenei Mm.439750.
Mm.482493.

3D structure databases

ProteinModelPortali E9Q706.
SMRi E9Q706. Positions 143-316, 813-1004.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000120080 ; ENSMUSP00000113421 ; ENSMUSG00000005580 .
GeneIDi 11515.
KEGGi mmu:11515.

Organism-specific databases

CTDi 115.
MGIi MGI:108450. Adcy9.

Phylogenomic databases

GeneTreei ENSGT00760000119042.
KOi K08049.

Miscellaneous databases

NextBioi 35555435.
SOURCEi Search...

Gene expression databases

Bgeei E9Q706.
ExpressionAtlasi E9Q706. baseline and differential.

Family and domain databases

Gene3Di 3.30.70.1230. 2 hits.
InterProi IPR001054. A/G_cyclase.
IPR018297. A/G_cyclase_CS.
IPR029787. Nucleotide_cyclase.
[Graphical view ]
Pfami PF00211. Guanylate_cyc. 2 hits.
[Graphical view ]
SMARTi SM00044. CYCc. 2 hits.
[Graphical view ]
SUPFAMi SSF55073. SSF55073. 2 hits.
PROSITEi PS00452. GUANYLATE_CYCLASE_1. 2 hits.
PS50125. GUANYLATE_CYCLASE_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q706_MOUSE
AccessioniPrimary (citable) accession number: E9Q706
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 26, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3