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E9Q706

- E9Q706_MOUSE

UniProt

E9Q706 - E9Q706_MOUSE

Protein
Submitted name:

Adenylate cyclase type 9

Gene

Adcy9

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. adenylate cyclase activity Source: MGI
    2. nucleotide binding Source: UniProtKB-KW

    GO - Biological processi

    1. activation of adenylate cyclase activity Source: MGI
    2. cAMP biosynthetic process Source: MGI
    3. intracellular signal transduction Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Nucleotide-bindingSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Adenylate cyclase type 9Imported
    Gene namesi
    Name:Adcy9Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 16

    Organism-specific databases

    MGIiMGI:108450. Adcy9.

    Subcellular locationi

    GO - Cellular componenti

    1. axon Source: Ensembl
    2. dendrite Source: Ensembl
    3. integral component of membrane Source: UniProtKB-KW
    4. plasma membrane Source: MGI

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    ArrayExpressiE9Q706.
    BgeeiE9Q706.

    Structurei

    3D structure databases

    ProteinModelPortaliE9Q706.
    SMRiE9Q706. Positions 143-316, 813-1004.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117304.

    Family and domain databases

    Gene3Di3.30.70.1230. 2 hits.
    InterProiIPR001054. A/G_cyclase.
    IPR018297. A/G_cyclase_CS.
    [Graphical view]
    PfamiPF00211. Guanylate_cyc. 2 hits.
    [Graphical view]
    SMARTiSM00044. CYCc. 2 hits.
    [Graphical view]
    SUPFAMiSSF55073. SSF55073. 2 hits.
    PROSITEiPS00452. GUANYLATE_CYCLASE_1. 2 hits.
    PS50125. GUANYLATE_CYCLASE_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9Q706-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQLPLYLSLF LGVVYSVLFE TFGYHFRNED CYPSPGPGAL HWELLSRALL     50
    HVCIHAIGIH LFVMSQVRSR STFLKVGQSI MHGKDLEVEK ALKERMIHSV 100
    MPRIIADDLM KQGDEESENS VKRHATSSPK NRKKKSSIQK APIAFRPFKM 150
    QQIEEVSILF ADIVGFTKMS ANKSAHALVG LLNDLFGRFD RLCEQTKCEK 200
    ISTLGDCYYC VAGCPEPRAD HAYCCIEMGL GMIKAIEQFC QEKKEMVNMR 250
    VGVHTGTVLC GILGMRRFKF DVWSNDVNLA NLMEQLGVAG KVHISEATAK 300
    YLDDRYEMED GRVIERLGQS VVADQLKGLK TYLISGQRAK ESHCSCAEAL 350
    LSGFEVIDDS RESSGPRGQG TASPGSVSDL AQTVKTFDNL KTCPSCGITF 400
    APKSEAGAEG GTVQNGCQDE PKTSTKASGG PNSKTQNGLL SPPAEEKLTN 450
    SQTSLCEILQ EKGRWAGVSL DQSALLPLRF KNIREKTDAH FVDVIKEDSL 500
    MKDYFFKPPI NQFSLNFLDQ ELERSYRTSY QEEVIKNSPV KTFASATFSS 550
    LLDVFLSTTV FLILSITCFL KYGATATPPP PAALAVFGAD LLLEVLSLIV 600
    SIRMVFFLED VMTCTKWLLE WIAGWLPRHC IGAILVSLPA LAVYSHITSE 650
    FETNIHVTMF TGSAVLVAVV HYCNFCQLSS WMRSSLATIV GAGLLLLLHI 700
    SLCQDSSIVM SPLDSAQNFS AQRNPCNSSV LQDGRRPASL IGKELILTFF 750
    LLLLLVWFLN REFEVSYRLH YHGDVEADLH RTKIQSMRDQ ADWLLRNIIP 800
    YHVAEQLKVS QTYSKNHDSG GVIFASIVNF SEFYEENYEG GKECYRVLNE 850
    LIGDFDELLS KPDYNSIEKI KTIGATYMAA SGLNTAQCQE GGHPQEHLRI 900
    LFEFAKEMMR VVDDFNNNML WFNFKLRVGF NHGPLTAGVI GTTKLLYDIW 950
    GDTVNIASRM DTTGVECRIQ VSEESYRVLS KMGYDFDYRG TVNVKGKGQM 1000
    KTYLYPKCTD NGVVPQHQLS ISPDIRVQVD GSIGRSPTDE IANLVPSVQY 1050
    SDKASLGSDD STQAKEARLS SKRSWREPVK AEERFPFGKA IEKDSCEDIG 1100
    VEEASELSKL NVSKSV 1116
    Length:1,116
    Mass (Da):124,388
    Last modified:April 5, 2011 - v1
    Checksum:i1C4E4A174C99CFAA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC087799 Genomic DNA. No translation available.
    AC132575 Genomic DNA. No translation available.
    RefSeqiNP_001278839.1. NM_001291910.1.

    Genome annotation databases

    EnsembliENSMUST00000120080; ENSMUSP00000113421; ENSMUSG00000005580.
    GeneIDi11515.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC087799 Genomic DNA. No translation available.
    AC132575 Genomic DNA. No translation available.
    RefSeqi NP_001278839.1. NM_001291910.1.

    3D structure databases

    ProteinModelPortali E9Q706.
    SMRi E9Q706. Positions 143-316, 813-1004.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000120080 ; ENSMUSP00000113421 ; ENSMUSG00000005580 .
    GeneIDi 11515.

    Organism-specific databases

    MGIi MGI:108450. Adcy9.

    Phylogenomic databases

    GeneTreei ENSGT00750000117304.

    Miscellaneous databases

    NextBioi 35555435.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9Q706.
    Bgeei E9Q706.

    Family and domain databases

    Gene3Di 3.30.70.1230. 2 hits.
    InterProi IPR001054. A/G_cyclase.
    IPR018297. A/G_cyclase_CS.
    [Graphical view ]
    Pfami PF00211. Guanylate_cyc. 2 hits.
    [Graphical view ]
    SMARTi SM00044. CYCc. 2 hits.
    [Graphical view ]
    SUPFAMi SSF55073. SSF55073. 2 hits.
    PROSITEi PS00452. GUANYLATE_CYCLASE_1. 2 hits.
    PS50125. GUANYLATE_CYCLASE_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9Q706_MOUSE
    AccessioniPrimary (citable) accession number: E9Q706
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3