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Protein

POU domain protein

Gene

Pou2f1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

TranscriptionUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:Pou2f1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:101898. Pou2f1.

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiE9Q6Z8.

Expressioni

Gene expression databases

BgeeiE9Q6Z8.
ExpressionAtlasiE9Q6Z8. baseline and differential.
GenevisibleiE9Q6Z8. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000124738.

Structurei

3D structure databases

ProteinModelPortaliE9Q6Z8.
SMRiE9Q6Z8. Positions 306-464.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini304 – 37875POU-specificInterPro annotationAdd
BLAST
Domaini403 – 46361Homeobox DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation
Contains 1 POU-specific domain.UniRule annotation
Contains 1 homeobox DNA-binding domain.UniRule annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3802. Eukaryota.
ENOG410XQ7X. LUCA.
GeneTreeiENSGT00760000118935.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_dom.
IPR000972. TF_octamer.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00029. OCTAMER.
PR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q6Z8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADGGAASQD ESSAAAAAAA DSRMNNPSET NKSSMESEDA STGTQTNGLD
60 70 80 90 100
FQKQPVPVGG AISTAQAQAF LGHLHQVQLA GTSLQAAAQS LNVQSKSSEE
110 120 130 140 150
SGDSQQSSQP SSQPPSVQSA IPQTQLMLAG GQITGLTLTP AQQQLLLQQA
160 170 180 190 200
QAQAQLLAAA VQQHSASQQH SAAGATISAS AATPMTQIPL SQPIQIAQDL
210 220 230 240 250
QQLQQLQQQN LNLQQFVLVH PTTNLQPAQF IISQTPQGQQ GLLQAQNLLT
260 270 280 290 300
QLPQQSQANL LQPQPSITLT SQPTTPTRTI AAASVQTLPQ SQSTPKRIDT
310 320 330 340 350
PSLEEPSDLE ELEQFAKTFK QRRIKLGFTQ GDVGLAMGKL YGNDFSQTTI
360 370 380 390 400
SRFEALNLSF KNMCKLKPLL EKWLNDAENL SSDSTASSPS ALNSPGLGAE
410 420 430 440 450
GLNRRRKKRT SIETNIRVAL EKSFMENQKP TSEDITLIAE QLNMEKEVIR
460 470 480 490 500
VWFCNRRQKE KRINPPSSGG TSSSPIKAIF PSPASLVATT PSLVTSSTAT
510 520 530 540 550
TLTVNPVLPL TSAAVTNLSL TGTTDSTSNN NTATVISTAP PASSAVTSPS
560 570 580 590 600
LSPSPSASAS TSEASSASET NTTQTTSTPL PSPLGASQVM VTTPGLQTAA
610 620 630 640 650
AALQGAAQLP ANASLAAMAA AAGLSPGLMA PSQFAAGGAL LSLSPGTLGS
660 670 680 690 700
ALSPALMSNS TLATIQALAS SGSLPITSLD ATGNLVFANA GGAPNIVTAP
710 720 730 740 750
LFLNPQNLSL LTSNPVSLVS AAAASTGNSA PTASLHASST STESIQSSLF
760
TVASASGPAS TTTAASKAQ
Length:769
Mass (Da):78,853
Last modified:April 5, 2011 - v1
Checksum:i4983FAE2C1FF76C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093371 Genomic DNA. No translation available.
RefSeqiNP_945150.2. NM_198932.3.
UniGeneiMm.245261.

Genome annotation databases

EnsembliENSMUST00000160908; ENSMUSP00000125444; ENSMUSG00000026565.
GeneIDi18986.
UCSCiuc007djz.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093371 Genomic DNA. No translation available.
RefSeqiNP_945150.2. NM_198932.3.
UniGeneiMm.245261.

3D structure databases

ProteinModelPortaliE9Q6Z8.
SMRiE9Q6Z8. Positions 306-464.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000124738.

Proteomic databases

PaxDbiE9Q6Z8.

Protocols and materials databases

DNASUi18986.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000160908; ENSMUSP00000125444; ENSMUSG00000026565.
GeneIDi18986.
UCSCiuc007djz.2. mouse.

Organism-specific databases

CTDi5451.
MGIiMGI:101898. Pou2f1.

Phylogenomic databases

eggNOGiKOG3802. Eukaryota.
ENOG410XQ7X. LUCA.
GeneTreeiENSGT00760000118935.

Miscellaneous databases

ChiTaRSiPou2f1. mouse.
NextBioi295362.
SOURCEiSearch...

Gene expression databases

BgeeiE9Q6Z8.
ExpressionAtlasiE9Q6Z8. baseline and differential.
GenevisibleiE9Q6Z8. MM.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.260.40. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_dom.
IPR000972. TF_octamer.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
[Graphical view]
PRINTSiPR00029. OCTAMER.
PR00028. POUDOMAIN.
SMARTiSM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q6Z8_MOUSE
AccessioniPrimary (citable) accession number: E9Q6Z8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 11, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.