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Protein
Submitted name:

Interleukin-1 receptor accessory protein

Gene

Il1rap

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin-1 receptor accessory proteinImported
Gene namesi
Name:Il1rapImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 16

Organism-specific databases

MGIiMGI:104975. Il1rap.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei363 – 38321HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 640620Sequence analysisPRO_5003244464Add
BLAST

Proteomic databases

MaxQBiE9Q6I2.
PaxDbiE9Q6I2.
PeptideAtlasiE9Q6I2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000022514.
ExpressionAtlasiE9Q6I2. baseline and differential.
GenevisibleiE9Q6I2. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000093843.

Structurei

3D structure databases

ProteinModelPortaliE9Q6I2.
SMRiE9Q6I2. Positions 24-345, 403-546.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini158 – 23073Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini243 – 348106Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini403 – 547145TIRInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IEPH. Eukaryota.
ENOG410ZRCQ. LUCA.
GeneTreeiENSGT00760000119071.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.40.50.10140. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR015621. IL-1_rcpt_fam.
IPR004074. IL-1_rcpt_I/II-typ.
IPR000157. TIR_dom.
[Graphical view]
PANTHERiPTHR11890. PTHR11890. 1 hit.
PfamiPF13895. Ig_2. 1 hit.
PF01582. TIR. 1 hit.
[Graphical view]
PRINTSiPR01536. INTRLKN1R12F.
SMARTiSM00409. IG. 3 hits.
SM00255. TIR. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 3 hits.
SSF52200. SSF52200. 1 hit.
PROSITEiPS50835. IG_LIKE. 2 hits.
PS50104. TIR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q6I2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLLWYLMSL SFYGILQSHA SERCDDWGLD TMRQIQVFED EPARIKCPLF
60 70 80 90 100
EHFLKYNYST AHSSGLTLIW YWTRQDRDLE EPINFRLPEN RISKEKDVLW
110 120 130 140 150
FRPTLLNDTG NYTCMLRNTT YCSKVAFPLE VVQKDSCFNS AMRFPVHKMY
160 170 180 190 200
IEHGIHKITC PNVDGYFPSS VKPSVTWYKG CTEIVDFHNV LPEGMNLSFF
210 220 230 240 250
IPLVSNNGNY TCVVTYPENG RLFHLTRTVT VKVVGSPKDA LPPQIYSPND
260 270 280 290 300
RVVYEKEPGE ELVIPCKVYF SFIMDSHNEV WWTIDGKKPD DVTVDITINE
310 320 330 340 350
SVSYSSTEDE TRTQILSIKK VTPEDLRRNY VCHARNTKGE AEQAAKVKQK
360 370 380 390 400
VIPPRYTVEL ACGFGATVFL VVVLIVVYHV YWLEMVLFYR AHFGTDETIL
410 420 430 440 450
DGKEYDIYVS YARNVEEEEF VLLTLRGVLE NEFGYKLCIF DRDSLPGGNT
460 470 480 490 500
VEAVFDFIQR SRRMIVVLSP DYVTEKSISM LEFKLGVMCQ NSIATKLIVV
510 520 530 540 550
EYRPLEQPHP GIMQLKESVS FVSWKGEKSK HSGSKFWKAL RLALPLRSLS
560 570 580 590 600
ASSGWNESCS SQSDISLDHV QRRSRLKEPP ELRSSERVSG AEPAPGTMSK
610 620 630 640
HRGKPSAACR CCVTYCEGES HLRSKSRAEM HTHPQWETHL
Length:640
Mass (Da):73,517
Last modified:April 5, 2011 - v1
Checksum:iF21C567FDC79B0C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154234 Genomic DNA. No translation available.
AC154601 Genomic DNA. No translation available.
CT009561 Genomic DNA. No translation available.
RefSeqiNP_001152789.1. NM_001159317.1.
UniGeneiMm.253424.

Genome annotation databases

EnsembliENSMUST00000166294; ENSMUSP00000128100; ENSMUSG00000022514.
GeneIDi16180.
UCSCiuc007yvf.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154234 Genomic DNA. No translation available.
AC154601 Genomic DNA. No translation available.
CT009561 Genomic DNA. No translation available.
RefSeqiNP_001152789.1. NM_001159317.1.
UniGeneiMm.253424.

3D structure databases

ProteinModelPortaliE9Q6I2.
SMRiE9Q6I2. Positions 24-345, 403-546.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000093843.

Proteomic databases

MaxQBiE9Q6I2.
PaxDbiE9Q6I2.
PeptideAtlasiE9Q6I2.

Protocols and materials databases

DNASUi16180.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000166294; ENSMUSP00000128100; ENSMUSG00000022514.
GeneIDi16180.
UCSCiuc007yvf.2. mouse.

Organism-specific databases

CTDi3556.
MGIiMGI:104975. Il1rap.

Phylogenomic databases

eggNOGiENOG410IEPH. Eukaryota.
ENOG410ZRCQ. LUCA.
GeneTreeiENSGT00760000119071.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000022514.
ExpressionAtlasiE9Q6I2. baseline and differential.
GenevisibleiE9Q6I2. MM.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.40.50.10140. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR015621. IL-1_rcpt_fam.
IPR004074. IL-1_rcpt_I/II-typ.
IPR000157. TIR_dom.
[Graphical view]
PANTHERiPTHR11890. PTHR11890. 1 hit.
PfamiPF13895. Ig_2. 1 hit.
PF01582. TIR. 1 hit.
[Graphical view]
PRINTSiPR01536. INTRLKN1R12F.
SMARTiSM00409. IG. 3 hits.
SM00255. TIR. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 3 hits.
SSF52200. SSF52200. 1 hit.
PROSITEiPS50835. IG_LIKE. 2 hits.
PS50104. TIR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q6I2_MOUSE
AccessioniPrimary (citable) accession number: E9Q6I2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 7, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.