E9Q6D8 (E9Q6D8_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Protein C6 Ensembl ENSMUSP00000125693

Gene names

Name:

C6 Ensembl ENSMUSP00000125693 MGI 88233

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000125693

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	931 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000125693

Ontologies

Keywords
Domain	EGF-like domain SAAS SAAS000436 Sushi SAAS SAAS000436
PTM	Disulfide bond SAAS SAAS000436
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	immune response Inferred from electronic annotation. Source: InterPro in utero embryonic development Inferred from genetic interaction PubMed 18947875. Source: MGI
Cellular_component	membrane attack complex Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E9Q6D8 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: 513A49FCB652D071	FASTA	931	104,457
	10 20 30 40 50 60 MTRHLTLCFI LLVMLIDKSE ACFCDHYPWT HWSSCSKSCN SGTQSRQRQV VVNDYYWKNL 70 80 90 100 110 120 CDKLCIKQET RECNLQTCPI NCVLGDYGTW SDCDPCTEKQ VKVKSVLRPS QFGGQPCTEP 130 140 150 160 170 180 LVTFQPCVPS KLCKIEETNC KNKFLCDSGR CIPSKLECNG ENDCGDNSDE RNCGRTKPVC 190 200 210 220 230 240 TRIYTPIPSV QLMGTGFHFL AGEPRGEVLD NSFTGGICKL VKTSRASNPY RVSANLENVN 250 260 270 280 290 300 FEVQTIEDDL KTEFYKNLIS FEKNKNEDSL SVDERTKFFP IPIFHFSEKN EHSHYSSAFN 310 320 330 340 350 360 KVIKASHKKD SSFIRIHKLI KVLNFTMKAT DLQLSDVFLK ALVHLPLEYN SAVYSRIFDD 370 380 390 400 410 420 FGTHYFTSGS LGGKYDLIYQ FSRQELQNSG LTEEEAQNCV QYETKKLKFL YMEIHKEDTC 430 440 450 460 470 480 TKNKLSEKYG GSFLQGSEKS ISLVQGGRSQ QAAALAWEKG TSGPEENVYS EWLESVKENP 490 500 510 520 530 540 AVVDYKLAPI TDLVRNIPCA VTKRNNLRRA LQEYAAKFDP CQCAPCPNNG RPRLSGTECL 550 560 570 580 590 600 CVCQSGTYGE NCERRSPGYK SDAVDGNWGC WSSWSACNAA YRRSRTRECN NPAPQRGGQS 610 620 630 640 650 660 CGGKDQQEED CTVSIMENVG QPCINDDEEM KEVDLAEPEA ESGCSQPPLP ENAFTWNEKK 670 680 690 700 710 720 LYSVGEEVEI SCLTGFTAVG FQYLRCLPDR TWSQGDVECQ RTSCLKPVVQ DVLTISPFQR 730 740 750 760 770 780 VYQIGESIEL TCPRGFVVAG PSRYTCKEDS WTPPISNSLT CEQGEQIFAW TCHLHVLSAL 790 800 810 820 830 840 RPNTCFPSSD SAYSEDLCIF DGGSSQYFTS SACKFLAGKC LNNTQSHFVH SGSCQEGLQL 850 860 870 880 890 900 EWGLERLKLA VNSTKRVSCG YNTCYDWENC SAHTSNCVCL LPPQCSKDEN QLYCVKIGSS 910 920 930 MREKTVNICT LGAVRCANIK VEILNPGRCP D

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000125693.
[2]	Ensembl Submitted (MAY-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000125693.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC102033 Genomic DNA. No translation available. AC117588 Genomic DNA. No translation available.
IPI	IPI00918363.
3D structure databases
ProteinModelPortal	E9Q6D8.
SMR	E9Q6D8. Positions 24-603, 638-813.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000162350; ENSMUSP00000125693; ENSMUSG00000022181.
Organism-specific databases
MGI	MGI:88233. C6.
Phylogenomic databases
GeneTree	ENSGT00550000074478.
OMA	CVCQSGT.
Gene expression databases
ArrayExpress	E9Q6D8.
Bgee	E9Q6D8.
Family and domain databases
InterPro	IPR013032. EGF-like_CS. IPR002350. Kazal_dom. IPR023415. LDLR_class-A_CS. IPR002172. LDrepeatLR_classA_rpt. IPR001862. MAC_perforin. IPR020864. MACPF. IPR020863. MACPF_CS. IPR000436. Sushi_SCR_CCP. IPR000884. Thrombospondin_1_rpt. [Graphical view]
Pfam	PF00057. Ldl_recept_a. 1 hit. PF01823. MACPF. 1 hit. PF00084. Sushi. 2 hits. PF00090. TSP_1. 3 hits. [Graphical view]
PRINTS	PR00764. COMPLEMENTC9.
SMART	SM00032. CCP. 2 hits. SM00192. LDLa. 1 hit. SM00457. MACPF. 1 hit. SM00209. TSP1. 3 hits. [Graphical view]
SUPFAM	SSF57535. Complement_control_module. 2 hits. SSF57424. LDL_rcpt_classA_cys-rich. 1 hit. SSF82895. TSP1. 3 hits.
PROSITE	PS00022. EGF_1. 1 hit. PS51465. KAZAL_2. 2 hits. PS01209. LDLRA_1. 1 hit. PS50068. LDLRA_2. 1 hit. PS00279. MACPF_1. 1 hit. PS51412. MACPF_2. 1 hit. PS50923. SUSHI. 2 hits. PS50092. TSP1. 3 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	35555346.
SOURCE	Search...

Entry information

Entry name

E9Q6D8_MOUSE

Accession

Primary (citable) accession number: E9Q6D8

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	May 1, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)