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E9Q6D8

- E9Q6D8_MOUSE

UniProt

E9Q6D8 - E9Q6D8_MOUSE

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Protein
Submitted name:

Protein C6

Gene
C6
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Biological processi

  1. immune response Source: InterPro
  2. in utero embryonic development Source: MGI
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_198562. Regulation of Complement cascade.
REACT_215211. Terminal pathway of complement.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein C6Imported
Gene namesi
Name:C6Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 15

Organism-specific databases

MGIiMGI:88233. C6.

Subcellular locationi

GO - Cellular componenti

  1. membrane attack complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Expressioni

Gene expression databases

ArrayExpressiE9Q6D8.
BgeeiE9Q6D8.

Structurei

3D structure databases

ProteinModelPortaliE9Q6D8.

Family & Domainsi

Keywords - Domaini

EGF-like domainSAAS annotations, SushiSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00550000074478.
OMAiCVCQSGT.
OrthoDBiEOG7NPFT9.
TreeFamiTF330498.

Family and domain databases

InterProiIPR013032. EGF-like_CS.
IPR002350. Kazal_dom.
IPR023415. LDLR_class-A_CS.
IPR002172. LDrepeatLR_classA_rpt.
IPR001862. MAC_perforin.
IPR020864. MACPF.
IPR020863. MACPF_CS.
IPR000436. Sushi_SCR_CCP.
IPR000884. Thrombospondin_1_rpt.
[Graphical view]
PfamiPF00057. Ldl_recept_a. 1 hit.
PF01823. MACPF. 1 hit.
PF00084. Sushi. 2 hits.
PF00090. TSP_1. 3 hits.
[Graphical view]
PRINTSiPR00764. COMPLEMENTC9.
SMARTiSM00032. CCP. 2 hits.
SM00192. LDLa. 1 hit.
SM00457. MACPF. 1 hit.
SM00209. TSP1. 3 hits.
[Graphical view]
SUPFAMiSSF57424. SSF57424. 1 hit.
SSF57535. SSF57535. 2 hits.
SSF82895. SSF82895. 3 hits.
PROSITEiPS00022. EGF_1. 1 hit.
PS51465. KAZAL_2. 2 hits.
PS01209. LDLRA_1. 1 hit.
PS50068. LDLRA_2. 1 hit.
PS00279. MACPF_1. 1 hit.
PS51412. MACPF_2. 1 hit.
PS50923. SUSHI. 2 hits.
PS50092. TSP1. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q6D8-1 [UniParc]FASTAAdd to Basket

« Hide

MTRHLTLCFI LLVMLIDKSE ACFCDHYPWT HWSSCSKSCN SGTQSRQRQV    50
VVNDYYWKNL CDKLCIKQET RECNLQTCPI NCVLGDYGTW SDCDPCTEKQ 100
VKVKSVLRPS QFGGQPCTEP LVTFQPCVPS KLCKIEETNC KNKFLCDSGR 150
CIPSKLECNG ENDCGDNSDE RNCGRTKPVC TRIYTPIPSV QLMGTGFHFL 200
AGEPRGEVLD NSFTGGICKL VKTSRASNPY RVSANLENVN FEVQTIEDDL 250
KTEFYKNLIS FEKNKNEDSL SVDERTKFFP IPIFHFSEKN EHSHYSSAFN 300
KVIKASHKKD SSFIRIHKLI KVLNFTMKAT DLQLSDVFLK ALVHLPLEYN 350
SAVYSRIFDD FGTHYFTSGS LGGKYDLIYQ FSRQELQNSG LTEEEAQNCV 400
QYETKKLKFL YMEIHKEDTC TKNKLSEKYG GSFLQGSEKS ISLVQGGRSQ 450
QAAALAWEKG TSGPEENVYS EWLESVKENP AVVDYKLAPI TDLVRNIPCA 500
VTKRNNLRRA LQEYAAKFDP CQCAPCPNNG RPRLSGTECL CVCQSGTYGE 550
NCERRSPGYK SDAVDGNWGC WSSWSACNAA YRRSRTRECN NPAPQRGGQS 600
CGGKDQQEED CTVSIMENVG QPCINDDEEM KEVDLAEPEA ESGCSQPPLP 650
ENAFTWNEKK LYSVGEEVEI SCLTGFTAVG FQYLRCLPDR TWSQGDVECQ 700
RTSCLKPVVQ DVLTISPFQR VYQIGESIEL TCPRGFVVAG PSRYTCKEDS 750
WTPPISNSLT CEQGEQIFAW TCHLHVLSAL RPNTCFPSSD SAYSEDLCIF 800
DGGSSQYFTS SACKFLAGKC LNNTQSHFVH SGSCQEGLQL EWGLERLKLA 850
VNSTKRVSCG YNTCYDWENC SAHTSNCVCL LPPQCSKDEN QLYCVKIGSS 900
MREKTVNICT LGAVRCANIK VEILNPGRCP D 931
Length:931
Mass (Da):104,457
Last modified:April 5, 2011 - v1
Checksum:i513A49FCB652D071
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC102033 Genomic DNA. No translation available.
AC117588 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000162350; ENSMUSP00000125693; ENSMUSG00000022181.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC102033 Genomic DNA. No translation available.
AC117588 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali E9Q6D8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000162350 ; ENSMUSP00000125693 ; ENSMUSG00000022181 .

Organism-specific databases

MGIi MGI:88233. C6.

Phylogenomic databases

GeneTreei ENSGT00550000074478.
OMAi CVCQSGT.
OrthoDBi EOG7NPFT9.
TreeFami TF330498.

Enzyme and pathway databases

Reactomei REACT_198562. Regulation of Complement cascade.
REACT_215211. Terminal pathway of complement.

Miscellaneous databases

NextBioi 35555346.
PROi E9Q6D8.
SOURCEi Search...

Gene expression databases

ArrayExpressi E9Q6D8.
Bgeei E9Q6D8.

Family and domain databases

InterProi IPR013032. EGF-like_CS.
IPR002350. Kazal_dom.
IPR023415. LDLR_class-A_CS.
IPR002172. LDrepeatLR_classA_rpt.
IPR001862. MAC_perforin.
IPR020864. MACPF.
IPR020863. MACPF_CS.
IPR000436. Sushi_SCR_CCP.
IPR000884. Thrombospondin_1_rpt.
[Graphical view ]
Pfami PF00057. Ldl_recept_a. 1 hit.
PF01823. MACPF. 1 hit.
PF00084. Sushi. 2 hits.
PF00090. TSP_1. 3 hits.
[Graphical view ]
PRINTSi PR00764. COMPLEMENTC9.
SMARTi SM00032. CCP. 2 hits.
SM00192. LDLa. 1 hit.
SM00457. MACPF. 1 hit.
SM00209. TSP1. 3 hits.
[Graphical view ]
SUPFAMi SSF57424. SSF57424. 1 hit.
SSF57535. SSF57535. 2 hits.
SSF82895. SSF82895. 3 hits.
PROSITEi PS00022. EGF_1. 1 hit.
PS51465. KAZAL_2. 2 hits.
PS01209. LDLRA_1. 1 hit.
PS50068. LDLRA_2. 1 hit.
PS00279. MACPF_1. 1 hit.
PS51412. MACPF_2. 1 hit.
PS50923. SUSHI. 2 hits.
PS50092. TSP1. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q6D8_MOUSE
AccessioniPrimary (citable) accession number: E9Q6D8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 3, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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