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E9Q6D8

- E9Q6D8_MOUSE

UniProt

E9Q6D8 - E9Q6D8_MOUSE

Protein
Submitted name:

Protein C6

Gene

C6

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. immune response Source: InterPro
    2. in utero embryonic development Source: MGI

    Enzyme and pathway databases

    ReactomeiREACT_198562. Regulation of Complement cascade.
    REACT_215211. Terminal pathway of complement.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein C6Imported
    Gene namesi
    Name:C6Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 15

    Organism-specific databases

    MGIiMGI:88233. C6.

    Subcellular locationi

    GO - Cellular componenti

    1. membrane attack complex Source: InterPro

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Expressioni

    Gene expression databases

    ArrayExpressiE9Q6D8.
    BgeeiE9Q6D8.

    Structurei

    3D structure databases

    ProteinModelPortaliE9Q6D8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    EGF-like domainSAAS annotation, SushiSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00550000074478.
    OMAiCVCQSGT.
    OrthoDBiEOG7NPFT9.
    TreeFamiTF330498.

    Family and domain databases

    InterProiIPR013032. EGF-like_CS.
    IPR002350. Kazal_dom.
    IPR023415. LDLR_class-A_CS.
    IPR002172. LDrepeatLR_classA_rpt.
    IPR001862. MAC_perforin.
    IPR020864. MACPF.
    IPR020863. MACPF_CS.
    IPR000436. Sushi_SCR_CCP.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view]
    PfamiPF00057. Ldl_recept_a. 1 hit.
    PF01823. MACPF. 1 hit.
    PF00084. Sushi. 2 hits.
    PF00090. TSP_1. 3 hits.
    [Graphical view]
    PRINTSiPR00764. COMPLEMENTC9.
    SMARTiSM00032. CCP. 2 hits.
    SM00192. LDLa. 1 hit.
    SM00457. MACPF. 1 hit.
    SM00209. TSP1. 3 hits.
    [Graphical view]
    SUPFAMiSSF57424. SSF57424. 1 hit.
    SSF57535. SSF57535. 2 hits.
    SSF82895. SSF82895. 3 hits.
    PROSITEiPS00022. EGF_1. 1 hit.
    PS51465. KAZAL_2. 2 hits.
    PS01209. LDLRA_1. 1 hit.
    PS50068. LDLRA_2. 1 hit.
    PS00279. MACPF_1. 1 hit.
    PS51412. MACPF_2. 1 hit.
    PS50923. SUSHI. 2 hits.
    PS50092. TSP1. 3 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9Q6D8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTRHLTLCFI LLVMLIDKSE ACFCDHYPWT HWSSCSKSCN SGTQSRQRQV    50
    VVNDYYWKNL CDKLCIKQET RECNLQTCPI NCVLGDYGTW SDCDPCTEKQ 100
    VKVKSVLRPS QFGGQPCTEP LVTFQPCVPS KLCKIEETNC KNKFLCDSGR 150
    CIPSKLECNG ENDCGDNSDE RNCGRTKPVC TRIYTPIPSV QLMGTGFHFL 200
    AGEPRGEVLD NSFTGGICKL VKTSRASNPY RVSANLENVN FEVQTIEDDL 250
    KTEFYKNLIS FEKNKNEDSL SVDERTKFFP IPIFHFSEKN EHSHYSSAFN 300
    KVIKASHKKD SSFIRIHKLI KVLNFTMKAT DLQLSDVFLK ALVHLPLEYN 350
    SAVYSRIFDD FGTHYFTSGS LGGKYDLIYQ FSRQELQNSG LTEEEAQNCV 400
    QYETKKLKFL YMEIHKEDTC TKNKLSEKYG GSFLQGSEKS ISLVQGGRSQ 450
    QAAALAWEKG TSGPEENVYS EWLESVKENP AVVDYKLAPI TDLVRNIPCA 500
    VTKRNNLRRA LQEYAAKFDP CQCAPCPNNG RPRLSGTECL CVCQSGTYGE 550
    NCERRSPGYK SDAVDGNWGC WSSWSACNAA YRRSRTRECN NPAPQRGGQS 600
    CGGKDQQEED CTVSIMENVG QPCINDDEEM KEVDLAEPEA ESGCSQPPLP 650
    ENAFTWNEKK LYSVGEEVEI SCLTGFTAVG FQYLRCLPDR TWSQGDVECQ 700
    RTSCLKPVVQ DVLTISPFQR VYQIGESIEL TCPRGFVVAG PSRYTCKEDS 750
    WTPPISNSLT CEQGEQIFAW TCHLHVLSAL RPNTCFPSSD SAYSEDLCIF 800
    DGGSSQYFTS SACKFLAGKC LNNTQSHFVH SGSCQEGLQL EWGLERLKLA 850
    VNSTKRVSCG YNTCYDWENC SAHTSNCVCL LPPQCSKDEN QLYCVKIGSS 900
    MREKTVNICT LGAVRCANIK VEILNPGRCP D 931
    Length:931
    Mass (Da):104,457
    Last modified:April 5, 2011 - v1
    Checksum:i513A49FCB652D071
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC102033 Genomic DNA. No translation available.
    AC117588 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000162350; ENSMUSP00000125693; ENSMUSG00000022181.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC102033 Genomic DNA. No translation available.
    AC117588 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E9Q6D8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000162350 ; ENSMUSP00000125693 ; ENSMUSG00000022181 .

    Organism-specific databases

    MGIi MGI:88233. C6.

    Phylogenomic databases

    GeneTreei ENSGT00550000074478.
    OMAi CVCQSGT.
    OrthoDBi EOG7NPFT9.
    TreeFami TF330498.

    Enzyme and pathway databases

    Reactomei REACT_198562. Regulation of Complement cascade.
    REACT_215211. Terminal pathway of complement.

    Miscellaneous databases

    NextBioi 35555346.
    PROi E9Q6D8.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9Q6D8.
    Bgeei E9Q6D8.

    Family and domain databases

    InterProi IPR013032. EGF-like_CS.
    IPR002350. Kazal_dom.
    IPR023415. LDLR_class-A_CS.
    IPR002172. LDrepeatLR_classA_rpt.
    IPR001862. MAC_perforin.
    IPR020864. MACPF.
    IPR020863. MACPF_CS.
    IPR000436. Sushi_SCR_CCP.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view ]
    Pfami PF00057. Ldl_recept_a. 1 hit.
    PF01823. MACPF. 1 hit.
    PF00084. Sushi. 2 hits.
    PF00090. TSP_1. 3 hits.
    [Graphical view ]
    PRINTSi PR00764. COMPLEMENTC9.
    SMARTi SM00032. CCP. 2 hits.
    SM00192. LDLa. 1 hit.
    SM00457. MACPF. 1 hit.
    SM00209. TSP1. 3 hits.
    [Graphical view ]
    SUPFAMi SSF57424. SSF57424. 1 hit.
    SSF57535. SSF57535. 2 hits.
    SSF82895. SSF82895. 3 hits.
    PROSITEi PS00022. EGF_1. 1 hit.
    PS51465. KAZAL_2. 2 hits.
    PS01209. LDLRA_1. 1 hit.
    PS50068. LDLRA_2. 1 hit.
    PS00279. MACPF_1. 1 hit.
    PS51412. MACPF_2. 1 hit.
    PS50923. SUSHI. 2 hits.
    PS50092. TSP1. 3 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9Q6D8_MOUSE
    AccessioniPrimary (citable) accession number: E9Q6D8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3