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Protein
Submitted name:

C-Jun-amino-terminal kinase-interacting protein 3

Gene

Mapk8ip3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • activation of JUN kinase activity Source: MGI
  • axon guidance Source: MGI
  • forebrain development Source: MGI
  • in utero embryonic development Source: MGI
  • JNK cascade Source: MGI
  • lung alveolus development Source: MGI
  • lung morphogenesis Source: MGI
  • post-embryonic development Source: MGI
  • protein localization Source: MGI
  • regulation of gene expression Source: MGI
  • respiratory gaseous exchange Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
C-Jun-amino-terminal kinase-interacting protein 3Imported
Gene namesi
Name:Mapk8ip3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1353598. Mapk8ip3.

Subcellular locationi

GO - Cellular componenti

  • axolemma Source: MGI
  • cytoplasm Source: MGI
  • dendrite Source: MGI
  • plasma membrane Source: MGI
  • smooth endoplasmic reticulum Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiE9Q6B6.
ExpressionAtlasiE9Q6B6. baseline and differential.
GenevisibleiE9Q6B6. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000085683.

Structurei

3D structure databases

ProteinModelPortaliE9Q6B6.
SMRiE9Q6B6. Positions 380-439.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00670000097546.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR019143. JNK/Rab-associated_protein-1_N.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF09744. Jnk-SapK_ap_N. 1 hit.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.

Sequencei

Sequence statusi: Complete.

E9Q6B6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMEIQMDEGG GVVVYQDDYC SGSVMSERVS GLAGSIYREF ERLIHCYDEE
60 70 80 90 100
VVKELMPLVV NVLENLDSVL SENQEHEVEL ELLREDNEQL LTQYEREKAL
110 120 130 140 150
RKQAEEKFIE FEDALEQEKK ELQIQVEHYE FQTRQLELKA KNYADQISRL
160 170 180 190 200
EERESEMKKE YNALHQRHTE MIQTYVEHIE RSKMQQVGGS GQTESSLPGR
210 220 230 240 250
SRKERPTSLN VFPLADGMCP NDEMSESGQS SAAATPSTTG TKSNTPTSSV
260 270 280 290 300
PSAAVTPLNE SLQPLGDYVS VTKNNKQARE KRNSRNMEVQ VTQEMRNVSI
310 320 330 340 350
GMGSSDEWSD VQDIIDSTPE LDVCPETRLE RTGSSPTQGI VNKAFGINTD
360 370 380 390 400
SLYHELSTAG SEVIGDVDEG ADLLGEFSGM GKEVGNLLLE NSQLLETKNA
410 420 430 440 450
LNVVKNDLIA KVDQLSGEQE VLKGELEAAK QAKVKLENRI KELEEELKRV
460 470 480 490 500
KSEAVTARRE PREEVEDVSS YLCTELDKIP MAQRRRFTRV EMARVLMERN
510 520 530 540 550
QYKERLMELQ EAVRWTEMIR ASREHPSVQE KKKSTIWQFF SRLFSSSSSP
560 570 580 590 600
PPAKRSYPSV NIHYKSPTAA GFSQRRSHAL CQISAGSRPL EFFPDDDCTS
610 620 630 640 650
SARREQKREQ YRQVREHVRN DDGRLQACGW SLPAKYKQLS PNGGQEDTRM
660 670 680 690 700
KNVPVPVYCR PLVEKDPSTK LWCAAGVNLS GWKPHEEDSS NGPKPVPGRD
710 720 730 740 750
PLTCDREGEG EPKSTHPSPE KKKAKETPEA DATSSRVWIL TSTLTTSKVV
760 770 780 790 800
IIDANQPGTI VDQFTVCNAH VLCISSIPAA SDSDYPPGEM FLDSDVNPED
810 820 830 840 850
SGADGVLAGI TLVGCATRCN VPRSNCSSRG DTPVLDKGQG DVATTANGKV
860 870 880 890 900
NPSQSTEEAT EATEVPDPGP SESEATTVRP GPLTEHVFTD PAPTPSSSTQ
910 920 930 940 950
PASENGSESN GTIVQPQVEP SGELSTTTSS AAPTMWLGAQ NGWLYVHSAV
960 970 980 990 1000
ANWKKCLHSI KLKDSVLSLV HVKGRVLVAL ADGTLAIFHR GEDGQWDLSN
1010 1020 1030 1040 1050
YHLMDLGHPH HSIRCMAVVN DRVWCGYKNK VHVIQPKTMQ IEKSFDAHPR
1060 1070 1080 1090 1100
RESQVRQLAW IGDGVWVSIR LDSTLRLYHA HTHQHLQDVD IEPYVSKMLG
1110 1120 1130 1140 1150
TGKLGFSFVR ITALLIAGNR LWVGTGNGVV ISIPLTETVV LHRGQLLGLR
1160 1170 1180 1190 1200
ANKTSPTSGE GTRPGGIIHV YGDDSSDKAA SSFIPYCSMA QAQLCFHGHR
1210 1220 1230 1240 1250
DAVKFFVSVP GNVLATLNGS VLDSPSEGPG PAAPAADAEG QKLKNALVLS
1260 1270 1280 1290 1300
GGEGYIDFRI GDGEDDETEE CAGDVNQTKP SLSKAERSHI IVWQVSYTPE
Length:1,300
Mass (Da):143,445
Last modified:April 5, 2011 - v1
Checksum:i1257BE83224175B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC166102 Genomic DNA. No translation available.
RefSeqiNP_001156925.1. NM_001163453.1.
UniGeneiMm.43081.

Genome annotation databases

EnsembliENSMUST00000121787; ENSMUSP00000113753; ENSMUSG00000024163.
GeneIDi30957.
UCSCiuc012amv.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC166102 Genomic DNA. No translation available.
RefSeqiNP_001156925.1. NM_001163453.1.
UniGeneiMm.43081.

3D structure databases

ProteinModelPortaliE9Q6B6.
SMRiE9Q6B6. Positions 380-439.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000085683.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000121787; ENSMUSP00000113753; ENSMUSG00000024163.
GeneIDi30957.
UCSCiuc012amv.1. mouse.

Organism-specific databases

CTDi23162.
MGIiMGI:1353598. Mapk8ip3.

Phylogenomic databases

GeneTreeiENSGT00670000097546.

Miscellaneous databases

NextBioi307444.
SOURCEiSearch...

Gene expression databases

BgeeiE9Q6B6.
ExpressionAtlasiE9Q6B6. baseline and differential.
GenevisibleiE9Q6B6. MM.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR019143. JNK/Rab-associated_protein-1_N.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF09744. Jnk-SapK_ap_N. 1 hit.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
    Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L.
    Mol. Cell. Proteomics 5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q6B6_MOUSE
AccessioniPrimary (citable) accession number: E9Q6B6
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 22, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.