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Protein
Submitted name:

Neural cell adhesion molecule 1

Gene

Ncam1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-375165. NCAM signaling for neurite out-growth.
R-MMU-419037. NCAM1 interactions.
R-MMU-445144. Signal transduction by L1.
R-MMU-5673001. RAF/MAP kinase cascade.

Names & Taxonomyi

Protein namesi
Submitted name:
Neural cell adhesion molecule 1Imported
Gene namesi
Name:Ncam1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:97281. Ncam1.

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_500324573920 – 725Sequence analysisAdd BLAST706

Proteomic databases

MaxQBiE9Q589.
PaxDbiE9Q589.
PeptideAtlasiE9Q589.
PRIDEiE9Q589.

Expressioni

Gene expression databases

BgeeiENSMUSG00000039542.
ExpressionAtlasiE9Q589. baseline and differential.
GenevisibleiE9Q589. MM.

Structurei

3D structure databases

ProteinModelPortaliE9Q589.
SMRiE9Q589.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 111Ig-likeInterPro annotationAdd BLAST92
Domaini116 – 189Ig-likeInterPro annotationAdd BLAST74
Domaini212 – 302Ig-likeInterPro annotationAdd BLAST91
Domaini309 – 404Ig-likeInterPro annotationAdd BLAST96
Domaini407 – 492Ig-likeInterPro annotationAdd BLAST86
Domaini500 – 599Fibronectin type-IIIInterPro annotationAdd BLAST100
Domaini601 – 696Fibronectin type-IIIInterPro annotationAdd BLAST96

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IQJI. Eukaryota.
ENOG410XTGB. LUCA.
GeneTreeiENSGT00860000133697.

Family and domain databases

CDDicd00063. FN3. 2 hits.
Gene3Di2.60.40.10. 8 hits.
InterProiView protein in InterPro
IPR003961. FN3_dom.
IPR036116. FN3_sf.
IPR007110. Ig-like_dom.
IPR036179. Ig-like_dom_sf.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR013106. Ig_V-set.
IPR033019. Ncam1.
IPR009138. Neural_cell_adh.
PANTHERiPTHR44059:SF2. PTHR44059:SF2. 1 hit.
PfamiView protein in Pfam
PF00041. fn3. 2 hits.
PF07679. I-set. 3 hits.
PRINTSiPR01838. NCAMFAMILY.
SMARTiView protein in SMART
SM00060. FN3. 2 hits.
SM00409. IG. 5 hits.
SM00408. IGc2. 5 hits.
SM00406. IGv. 2 hits.
SUPFAMiSSF48726. SSF48726. 5 hits.
SSF49265. SSF49265. 1 hit.
PROSITEiView protein in PROSITE
PS50853. FN3. 2 hits.
PS50835. IG_LIKE. 5 hits.

Sequencei

Sequence statusi: Complete.

E9Q589-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRTKDLIWT LFFLGTAVSL QVDIVPSQGE ISVGESKFFL CQVAGDAKDK
60 70 80 90 100
DISWFSPNGE KLSPNQQRIS VVWNDDDSST LTIYNANIDD AGIYKCVVTA
110 120 130 140 150
EDGTQSEATV NVKIFQKLMF KNAPTPQEFK EGEDAVIVCD VVSSLPPTII
160 170 180 190 200
WKHKGRDVIL KKDVRFIVLS NNYLQIRGIK KTDEGTYRCE GRILARGEIN
210 220 230 240 250
FKDIQVIVNV PPTVQARQSI VNATANLGQS VTLVCDADGF PEPTMSWTKD
260 270 280 290 300
GEPIENEEED DEKHIFSDDS SELTIRNVDK NDEAEYVCIA ENKAGEQDAS
310 320 330 340 350
IHLKVFAKPK ITYVENQTAM ELEEQVTLTC EASGDPIPSI TWRTSTRNIS
360 370 380 390 400
SEEKTLDGHM VVRSHARVSS LTLKSIQYTD AGEYICTASN TIGQDSQSMY
410 420 430 440 450
LEVQYAPKLQ GPVAVYTWEG NQVNITCEVF AYPSATISWF RDGQLLPSSN
460 470 480 490 500
YSNIKIYNTP SASYLEVTPD SENDFGNYNC TAVNRIGQES LEFILVQADT
510 520 530 540 550
PSSPSIDRVE PYSSTAQVQF DEPEATGGVP ILKYKAEWKS LGEESWHFKW
560 570 580 590 600
YDAKEANMEG IVTIMGLKPE TRYSVRLAAL NGKGLGEISA ATEFKTQPVR
610 620 630 640 650
EPSAPKLEGQ MGEDGNSIKV NLIKQDDGGS PIRHYLVKYR ALASEWKPEI
660 670 680 690 700
RLPSGSDHVM LKSLDWNAEY EVYVVAENQQ GKSKAAHFVF RTSAQPTAIP
710 720
ATLGGSSTSY TLVSLLFSAV TLLLL
Length:725
Mass (Da):80,358
Last modified:April 5, 2011 - v1
Checksum:iE08F947CD65FF22C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC117630 Genomic DNA. No translation available.
AC140447 Genomic DNA. No translation available.
CT025676 Genomic DNA. No translation available.
RefSeqiNP_035005.2. NM_010875.3.
UniGeneiMm.439182.
Mm.4974.

Genome annotation databases

EnsembliENSMUST00000114476; ENSMUSP00000110120; ENSMUSG00000039542.
GeneIDi17967.
UCSCiuc009pjh.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiE9Q589_MOUSE
AccessioniPrimary (citable) accession number: E9Q589
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 25, 2017
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported