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Protein
Submitted name:

Dynactin subunit 1

Gene

Dctn1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Dynactin subunit 1Imported
Gene namesi
Name:Dctn1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:107745. Dctn1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiE9Q586.
MaxQBiE9Q586.
PaxDbiE9Q586.
PeptideAtlasiE9Q586.
PRIDEiE9Q586.

Expressioni

Gene expression databases

BgeeiE9Q586.
ExpressionAtlasiE9Q586. baseline and differential.
GenevisibleiE9Q586. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000109552.

Structurei

3D structure databases

ProteinModelPortaliE9Q586.
SMRiE9Q586. Positions 8-81, 401-501.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini31 – 7343CAP-GlyInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili180 – 315136Sequence analysisAdd
BLAST
Coiled coili323 – 34624Sequence analysisAdd
BLAST
Coiled coili351 – 503153Sequence analysisAdd
BLAST
Coiled coili915 – 100692Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0971. Eukaryota.
COG5244. LUCA.
GeneTreeiENSGT00760000119173.
OrthoDBiEOG79W94B.

Family and domain databases

Gene3Di2.30.30.190. 1 hit.
InterProiIPR000938. CAP-Gly_domain.
IPR027663. DCTN1.
IPR022157. Dynactin.
[Graphical view]
PANTHERiPTHR18916:SF40. PTHR18916:SF40. 1 hit.
PfamiPF01302. CAP_GLY. 1 hit.
PF12455. Dynactin. 1 hit.
[Graphical view]
SMARTiSM01052. CAP_GLY. 1 hit.
[Graphical view]
SUPFAMiSSF74924. SSF74924. 1 hit.
PROSITEiPS00845. CAP_GLY_1. 1 hit.
PS50245. CAP_GLY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q586-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTEASARPL RVGSRVEVIG KGHRGTVAYV GATLFATGKW VGVILDEAKG
60 70 80 90 100
KNDGTVQGRK YFTCDEGHGI FVRQSQIQVF EDGADTTSPE TPDSSASKVL
110 120 130 140 150
KREGADAAAK TSKLPTRPAS TGVAGPSSSL GPSGSASAGE LSSSEPSTPA
160 170 180 190 200
QTPLAAPIIP TPALTSPGAA PPLPSPSKEE EGLRAQVRDL EEKLETLRLK
210 220 230 240 250
RSEDKAKLKE LEKHKIQLEQ VQEWKSKMQE QQADLQRRLK EARKEAKEAL
260 270 280 290 300
EAKERYMEEM ADTADAIEMA TLDKEMAEER AESLQQEVEA LKERVDELTT
310 320 330 340 350
DLEILKAEIE EKGSDGAASS YQLKQLEEQN ARLKDALVRM RDLSSSEKQE
360 370 380 390 400
HVKLQKLMEK KNQELEVVRQ QRERLQEELS QAESTIDELK EQVDAALGAE
410 420 430 440 450
EMVEMLTDRN LNLEEKVREL RETVGDLEAM NEMNDELQEN ARETELELRE
460 470 480 490 500
QLDMAGARVR EAQKRVEAAQ ETVADYQQTI KKYRQLTAHL QDVNRELTNQ
510 520 530 540 550
QEASVERQQQ PPPETFDFKI KFAETKAHAK AIEMELRQME VAQANRHMSL
560 570 580 590 600
LTAFMPDSFL RPGGDHDCVL VLLLMPRLIC KAELIRKQAQ EKFDLSENCS
610 620 630 640 650
ERPGLRGAAG EQLSFAAGLV YSLSLLQATL HRYEHALSQC SVDVYKKVGS
660 670 680 690 700
LYPEMSAHER SLDFLIELLH KDQLDETVNV EPLTKAIKYY QHLYSIHLAE
710 720 730 740 750
QPEDSTMQLA DHIKFTQSAL DCMGVEVGRL RAFLQGGQEA TDIALLLRDL
760 770 780 790 800
ETSCSDTRQF CKKIRRRMPG TDAPGIPAAL AFGSQVSDTL LDCRKHLTWV
810 820 830 840 850
VAVLQEVAAA AAQLIAPLAE NEGLPVAALE ELAFKASEQI YGSPSSSPYE
860 870 880 890 900
CLRQSCTILI STMNKLATAM QEGEYDAERP PSKPPPVELR AAALRAEITD
910 920 930 940 950
AEGLGLKLED RETVIKELKK SLKIKGEELS EANVRLSLLE KKLDSAAKDA
960 970 980 990 1000
DERIEKVQTR LDETQTLLRK KEKDFEETMD ALQADIDQLE AEKAELKQRL
1010 1020 1030 1040 1050
NSQSKRTIEG LRGPPPSGIA TLVSGIAGGG APGQAPGALP GPGLVKDSPL
1060 1070 1080 1090 1100
LLQQISAMRL HISQLQHENS ILRGAQMKAS LAALPPLHVA KLSLPPHEGP
1110 1120 1130 1140 1150
GGNLVAGALY RKTSQLLEKL NQLSTHTHVV DITRSSPAAK SPSAQLMEQV
1160 1170 1180 1190 1200
AQLKSLSDTI EKLKDEVLKE TVTQRPGATV PTDFATFPSS AFLRAKEEQQ
1210 1220 1230
DDTVYMGKVT FSCAAGLGQR HRLVLTQEQL HQLHSRLIS
Length:1,239
Mass (Da):136,848
Last modified:April 5, 2011 - v1
Checksum:iAF1C01FC4CD1638F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC160400 Genomic DNA. No translation available.
RefSeqiNP_001185796.1. NM_001198867.1.
UniGeneiMm.6919.

Genome annotation databases

EnsembliENSMUST00000077407; ENSMUSP00000076623; ENSMUSG00000031865.
GeneIDi13191.
UCSCiuc009cna.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC160400 Genomic DNA. No translation available.
RefSeqiNP_001185796.1. NM_001198867.1.
UniGeneiMm.6919.

3D structure databases

ProteinModelPortaliE9Q586.
SMRiE9Q586. Positions 8-81, 401-501.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000109552.

Proteomic databases

EPDiE9Q586.
MaxQBiE9Q586.
PaxDbiE9Q586.
PeptideAtlasiE9Q586.
PRIDEiE9Q586.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000077407; ENSMUSP00000076623; ENSMUSG00000031865.
GeneIDi13191.
UCSCiuc009cna.2. mouse.

Organism-specific databases

CTDi1639.
MGIiMGI:107745. Dctn1.

Phylogenomic databases

eggNOGiKOG0971. Eukaryota.
COG5244. LUCA.
GeneTreeiENSGT00760000119173.
OrthoDBiEOG79W94B.

Miscellaneous databases

ChiTaRSiDctn1. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiE9Q586.
ExpressionAtlasiE9Q586. baseline and differential.
GenevisibleiE9Q586. MM.

Family and domain databases

Gene3Di2.30.30.190. 1 hit.
InterProiIPR000938. CAP-Gly_domain.
IPR027663. DCTN1.
IPR022157. Dynactin.
[Graphical view]
PANTHERiPTHR18916:SF40. PTHR18916:SF40. 1 hit.
PfamiPF01302. CAP_GLY. 1 hit.
PF12455. Dynactin. 1 hit.
[Graphical view]
SMARTiSM01052. CAP_GLY. 1 hit.
[Graphical view]
SUPFAMiSSF74924. SSF74924. 1 hit.
PROSITEiPS00845. CAP_GLY_1. 1 hit.
PS50245. CAP_GLY_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q586_MOUSE
AccessioniPrimary (citable) accession number: E9Q586
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 6, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.