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Protein
Submitted name:

Caspase-12

Gene

Casp12

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Thiol proteaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Caspase-12Imported
Gene namesi
Name:Casp12Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi

Organism-specific databases

MGIiMGI:1312922 Casp12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiE9Q575
PRIDEiE9Q575

Expressioni

Gene expression databases

BgeeiENSMUSG00000025887
ExpressionAtlasiE9Q575 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9Q575
SMRiE9Q575
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini104 – 232CASPASE_P20InterPro annotationAdd BLAST129
Domaini262 – 347CASPASE_P10InterPro annotationAdd BLAST86

Sequence similaritiesi

Belongs to the peptidase C14A family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3573 Eukaryota
ENOG410ZQIE LUCA
GeneTreeiENSGT00910000144131

Family and domain databases

CDDicd00032 CASc, 1 hit
InterProiView protein in InterPro
IPR029030 Caspase-like_dom_sf
IPR035713 Caspase_12
IPR033139 Caspase_cys_AS
IPR016129 Caspase_his_AS
IPR002138 Pept_C14_p10
IPR001309 Pept_C14_p20
IPR015917 Pept_C14A
PANTHERiPTHR10454:SF134 PTHR10454:SF134, 1 hit
PRINTSiPR00376 IL1BCENZYME
SMARTiView protein in SMART
SM00115 CASc, 1 hit
SUPFAMiSSF52129 SSF52129, 1 hit
PROSITEiView protein in PROSITE
PS01122 CASPASE_CYS, 1 hit
PS01121 CASPASE_HIS, 1 hit
PS50207 CASPASE_P10, 1 hit
PS50208 CASPASE_P20, 1 hit

Sequencei

Sequence statusi: Complete.

E9Q575-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARRTHERD PIYKIKEFSN DEDDGPQKIC TPSSPSESKR KVEDDEMEVN
60 70 80 90 100
AGLAHESHLM LTAPHGLQSS EVQDTLKLCP RDQFCKIKTE RAKEIYPVME
110 120 130 140 150
KEGRTRLALI ICNKKFDYLF DRDNADTDIL NMQELLENLG YSVVLKENLT
160 170 180 190 200
AQEMETELMQ FAGRPEHQSS DSTFLVFMSH GILEGICGVK HRNKKPDVLH
210 220 230 240 250
DDTIFKIFNN SNCRSLRNKP KILIMQACRG RYNGTIWVST NKGIATADTD
260 270 280 290 300
EERVLSCKWN NSITKAHVET DFIAFKSSTP HNISWKVGKT GSLFISKLID
310 320 330 340
CFKKYCWCYH LEEIFRKVQH SFEVPGELTQ MPTIERVSMT RYFYLFPGN
Length:349
Mass (Da):40,250
Last modified:April 5, 2011 - v1
Checksum:i5DE0DC1FFF7D27A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC104914 Genomic DNA No translation available.
AC141637 Genomic DNA No translation available.
RefSeqiXP_006509903.1, XM_006509840.2
UniGeneiMm.42163

Genome annotation databases

EnsembliENSMUST00000151332; ENSMUSP00000122201; ENSMUSG00000025887
GeneIDi12364
UCSCiuc012gno.1 mouse

Similar proteinsi

Entry informationi

Entry nameiE9Q575_MOUSE
AccessioniPrimary (citable) accession number: E9Q575
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 23, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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