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E9Q4T8

- E9Q4T8_MOUSE

UniProt

E9Q4T8 - E9Q4T8_MOUSE

Protein
Submitted name:

Cullin-3

Gene

Cul3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Protein inferred from homologyi
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    • History
      Entry version 26 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. cyclin binding Source: MGI
    2. protein binding Source: MGI
    3. protein heterodimerization activity Source: MGI
    4. protein homodimerization activity Source: MGI

    GO - Biological processi

    1. cell morphogenesis Source: MGI
    2. cyclin catabolic process Source: MGI
    3. gastrulation Source: MGI
    4. in utero embryonic development Source: MGI
    5. proteasome-mediated ubiquitin-dependent protein catabolic process Source: MGI
    6. trophectodermal cellular morphogenesis Source: MGI
    7. Wnt signaling pathway Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Cullin-3Imported
    Gene namesi
    Name:Cul3Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 1

    Organism-specific databases

    MGIiMGI:1347360. Cul3.

    Subcellular locationi

    GO - Cellular componenti

    1. cullin-RING ubiquitin ligase complex Source: InterPro
    2. Golgi apparatus Source: MGI
    3. nucleus Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiE9Q4T8.
    BgeeiE9Q4T8.

    Structurei

    3D structure databases

    ProteinModelPortaliE9Q4T8.
    SMRiE9Q4T8. Positions 21-702.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cullin family.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00730000110449.

    Family and domain databases

    Gene3Di1.10.10.10. 2 hits.
    InterProiIPR016157. Cullin_CS.
    IPR016158. Cullin_homology.
    IPR001373. Cullin_N.
    IPR019559. Cullin_neddylation_domain.
    IPR016159. Cullin_repeat-like_dom.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF00888. Cullin. 1 hit.
    PF10557. Cullin_Nedd8. 1 hit.
    [Graphical view]
    SMARTiSM00182. CULLIN. 1 hit.
    SM00884. Cullin_Nedd8. 1 hit.
    [Graphical view]
    SUPFAMiSSF74788. SSF74788. 1 hit.
    SSF75632. SSF75632. 1 hit.
    PROSITEiPS01256. CULLIN_1. 1 hit.
    PS50069. CULLIN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9Q4T8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSNLSKGTGS RKDTKMRIRA FPVREDVLNS LNNNFLQTLN QAWNDHQTAM    50
    VMIRDILMYM DRVYVQQNNV ENVYNLGLII FRDQVVRYGC IRDHLRQTLL 100
    DMIARERKGE VVDRGAIRNA CQMLMILGLE GRSVYEEDFE APFLEMSAEF 150
    FQMESQKFLA ENSASVYIKK VEARINEEIE RVMHCLDKST EEPIVKVVER 200
    ELISKHMKTI VEMENSGLVH MLKNGKTEDL ACMYKLFSRV PNGLKTMCEC 250
    MSCYLREQGK ALVSEEGEGK NPVDYIQGLL DLKSRFDRFL QESFNNDRLF 300
    KQTIAGDFEY FLNLNSRSPE YLSLFIDDKL KKGVKGLTEQ EVETILDKAM 350
    VLFRFMQEKD VFERYYKQHL ARRLLTNKSV SDDSEKNMIS KLKTECGCQF 400
    TSKLEGMFRD MSISNTTMDE FRQHLQATGV SLGGVDLTVR VLTTGYWPTQ 450
    SATPKCNIPP APRHAFEIFR RFYLAKHSGR QLTLQHHMGS ADLNATFYGP 500
    VKKEDGSEVG VGGAQVTGSN TRKHILQVST FQMTILMLFN NREKYTFEEI 550
    QQETDIPERE LVRALQSLAC GKPTQRVLTK EPKSKEIESG HIFTVNDQFT 600
    SKLHRVKIQT VAAKQGESDP ERKETRQKVD DDRKHEIEAA IVRIMKSRKK 650
    MQHNVLVAEV TQQLKARFLP SPVVIKKRIE GLIEREYLAR TPEDRKVYTY 700
    VA 702
    Length:702
    Mass (Da):81,111
    Last modified:April 5, 2011 - v1
    Checksum:i09608E18C7E70FB0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC161416 Genomic DNA. No translation available.
    AC166157 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000164108; ENSMUSP00000131891; ENSMUSG00000004364.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC161416 Genomic DNA. No translation available.
    AC166157 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E9Q4T8.
    SMRi E9Q4T8. Positions 21-702.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000164108 ; ENSMUSP00000131891 ; ENSMUSG00000004364 .

    Organism-specific databases

    MGIi MGI:1347360. Cul3.

    Phylogenomic databases

    GeneTreei ENSGT00730000110449.

    Miscellaneous databases

    ChiTaRSi CUL3. mouse.
    NextBioi 35555159.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9Q4T8.
    Bgeei E9Q4T8.

    Family and domain databases

    Gene3Di 1.10.10.10. 2 hits.
    InterProi IPR016157. Cullin_CS.
    IPR016158. Cullin_homology.
    IPR001373. Cullin_N.
    IPR019559. Cullin_neddylation_domain.
    IPR016159. Cullin_repeat-like_dom.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF00888. Cullin. 1 hit.
    PF10557. Cullin_Nedd8. 1 hit.
    [Graphical view ]
    SMARTi SM00182. CULLIN. 1 hit.
    SM00884. Cullin_Nedd8. 1 hit.
    [Graphical view ]
    SUPFAMi SSF74788. SSF74788. 1 hit.
    SSF75632. SSF75632. 1 hit.
    PROSITEi PS01256. CULLIN_1. 1 hit.
    PS50069. CULLIN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9Q4T8_MOUSE
    AccessioniPrimary (citable) accession number: E9Q4T8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 26 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3