E9Q4T8 (E9Q4T8_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cullin-3 Ensembl ENSMUSP00000131891

Gene names

Name:

Cul3 Ensembl ENSMUSP00000131891 MGI 1347360

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000131891

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	702 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities	Belongs to the cullin family. RuleBase RU003829
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000131891

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	Wnt receptor signaling pathway Inferred from direct assay PubMed 19056892. Source: MGI cyclin catabolic process Inferred from sequence or structural similarity PubMed 10500095. Source: MGI gastrulation Inferred from mutant phenotype PubMed 10500095. Source: MGI trophectodermal cellular morphogenesis Inferred from mutant phenotype PubMed 10500095. Source: MGI
Cellular_component	Golgi apparatus Inferred from direct assay PubMed 10500095. Source: MGI cullin-RING ubiquitin ligase complex Inferred from electronic annotation. Source: InterPro nucleus Inferred from direct assay PubMed 10500095. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	E9Q4T8 [UniParc]. Last modified April 5, 2011. Version 1. Checksum: 09608E18C7E70FB0	FASTA	702	81,111
	10 20 30 40 50 60 MSNLSKGTGS RKDTKMRIRA FPVREDVLNS LNNNFLQTLN QAWNDHQTAM VMIRDILMYM 70 80 90 100 110 120 DRVYVQQNNV ENVYNLGLII FRDQVVRYGC IRDHLRQTLL DMIARERKGE VVDRGAIRNA 130 140 150 160 170 180 CQMLMILGLE GRSVYEEDFE APFLEMSAEF FQMESQKFLA ENSASVYIKK VEARINEEIE 190 200 210 220 230 240 RVMHCLDKST EEPIVKVVER ELISKHMKTI VEMENSGLVH MLKNGKTEDL ACMYKLFSRV 250 260 270 280 290 300 PNGLKTMCEC MSCYLREQGK ALVSEEGEGK NPVDYIQGLL DLKSRFDRFL QESFNNDRLF 310 320 330 340 350 360 KQTIAGDFEY FLNLNSRSPE YLSLFIDDKL KKGVKGLTEQ EVETILDKAM VLFRFMQEKD 370 380 390 400 410 420 VFERYYKQHL ARRLLTNKSV SDDSEKNMIS KLKTECGCQF TSKLEGMFRD MSISNTTMDE 430 440 450 460 470 480 FRQHLQATGV SLGGVDLTVR VLTTGYWPTQ SATPKCNIPP APRHAFEIFR RFYLAKHSGR 490 500 510 520 530 540 QLTLQHHMGS ADLNATFYGP VKKEDGSEVG VGGAQVTGSN TRKHILQVST FQMTILMLFN 550 560 570 580 590 600 NREKYTFEEI QQETDIPERE LVRALQSLAC GKPTQRVLTK EPKSKEIESG HIFTVNDQFT 610 620 630 640 650 660 SKLHRVKIQT VAAKQGESDP ERKETRQKVD DDRKHEIEAA IVRIMKSRKK MQHNVLVAEV 670 680 690 700 TQQLKARFLP SPVVIKKRIE GLIEREYLAR TPEDRKVYTY VA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000131891.
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000131891.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC161416 Genomic DNA. No translation available. AC166157 Genomic DNA. No translation available.
IPI	IPI00988265.
3D structure databases
ProteinModelPortal	E9Q4T8.
SMR	E9Q4T8. Positions 21-702.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000164108; ENSMUSP00000131891; ENSMUSG00000004364.
Organism-specific databases
MGI	MGI:1347360. Cul3.
Phylogenomic databases
GeneTree	ENSGT00550000074299.
Gene expression databases
ArrayExpress	E9Q4T8.
Bgee	E9Q4T8.
Family and domain databases
Gene3D	1.10.10.10. 2 hits.
InterPro	IPR016157. Cullin_CS. IPR016158. Cullin_homology. IPR001373. Cullin_N. IPR019559. Cullin_neddylation_domain. IPR016159. Cullin_repeat-like_dom. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
Pfam	PF00888. Cullin. 1 hit. PF10557. Cullin_Nedd8. 1 hit. [Graphical view]
SMART	SM00182. CULLIN. 1 hit. SM00884. Cullin_Nedd8. 1 hit. [Graphical view]
SUPFAM	SSF75632. Cullin_homology. 1 hit. SSF74788. Cullin_repeat-like. 1 hit.
PROSITE	PS01256. CULLIN_1. 1 hit. PS50069. CULLIN_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	CUL3. mouse.
NextBio	35555159.
SOURCE	Search...

Entry information

Entry name

E9Q4T8_MOUSE

Accession

Primary (citable) accession number: E9Q4T8

Entry history

Integrated into UniProtKB/TrEMBL:	April 5, 2011
Last sequence update:	April 5, 2011
Last modified:	May 1, 2013
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)