ID   E9Q4N6_MOUSE            Unreviewed;      1762 AA.
AC   E9Q4N6;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 83.
DE   SubName: Full=AT rich interactive domain 1B (SWI-like) {ECO:0000313|Ensembl:ENSMUSP00000111465.2};
GN   Name=Arid1b {ECO:0000313|Ensembl:ENSMUSP00000111465.2,
GN   ECO:0000313|MGI:MGI:1926129};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000111465.2, ECO:0000313|Proteomes:UP000000589};
RN   [1] {ECO:0000313|Ensembl:ENSMUSP00000111465.2, ECO:0000313|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000111465.2,
RC   ECO:0000313|Proteomes:UP000000589};
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2] {ECO:0007829|PubMed:21183079}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
RN   [3] {ECO:0007829|PubMed:24129315}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=24129315;
RA   Guo A., Gu H., Zhou J., Mulhern D., Wang Y., Lee K.A., Yang V., Aguiar M.,
RA   Kornhauser J., Jia X., Ren J., Beausoleil S.A., Silva J.C., Vemulapalli V.,
RA   Bedford M.T., Comb M.J.;
RT   "Immunoaffinity enrichment and mass spectrometry analysis of protein
RT   methylation.";
RL   Mol. Cell. Proteomics 13:372-387(2014).
RN   [4] {ECO:0000313|Ensembl:ENSMUSP00000111465.2}
RP   IDENTIFICATION.
RC   STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000111465.2};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   SMR; E9Q4N6; -.
DR   jPOST; E9Q4N6; -.
DR   MaxQB; E9Q4N6; -.
DR   PeptideAtlas; E9Q4N6; -.
DR   ProteomicsDB; 346807; -.
DR   Antibodypedia; 19980; 197 antibodies from 27 providers.
DR   Ensembl; ENSMUST00000115799.2; ENSMUSP00000111465.2; ENSMUSG00000069729.15.
DR   AGR; MGI:1926129; -.
DR   MGI; MGI:1926129; Arid1b.
DR   VEuPathDB; HostDB:ENSMUSG00000069729; -.
DR   GeneTree; ENSGT00940000155634; -.
DR   HOGENOM; CLU_000974_1_0_1; -.
DR   ChiTaRS; Arid1b; mouse.
DR   Proteomes; UP000000589; Chromosome 17.
DR   Bgee; ENSMUSG00000069729; Expressed in rostral migratory stream and 234 other cell types or tissues.
DR   ExpressionAtlas; E9Q4N6; baseline and differential.
DR   GO; GO:0035060; C:brahma complex; IEA:InterPro.
DR   GO; GO:0016514; C:SWI/SNF complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR   CDD; cd16877; ARID_ARID1B; 1.
DR   Gene3D; 1.10.150.60; ARID DNA-binding domain; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR038040; ARID_ARID1B.
DR   InterPro; IPR001606; ARID_dom.
DR   InterPro; IPR036431; ARID_dom_sf.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR021906; BAF250/Osa.
DR   InterPro; IPR033388; BAF250_C.
DR   PANTHER; PTHR12656:SF11; AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 1B; 1.
DR   PANTHER; PTHR12656; BRG-1 ASSOCIATED FACTOR 250 BAF250; 1.
DR   Pfam; PF01388; ARID; 1.
DR   Pfam; PF12031; BAF250_C; 1.
DR   SMART; SM01014; ARID; 1.
DR   SMART; SM00501; BRIGHT; 1.
DR   SUPFAM; SSF46774; ARID-like; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS51011; ARID; 1.
PE   1: Evidence at protein level;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Proteomics identification {ECO:0007829|EPD:E9Q4N6,
KW   ECO:0007829|MaxQB:E9Q4N6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT   DOMAIN          579..670
FT                   /note="ARID"
FT                   /evidence="ECO:0000259|PROSITE:PS51011"
FT   REGION          1..351
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          419..452
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          478..572
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          672..778
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          805..843
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          923..1090
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1221..1294
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1347..1385
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1397..1417
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        33..47
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        76..148
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        155..169
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        178..215
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        230..277
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        285..325
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        487..501
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        502..517
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        527..571
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        685..717
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        733..773
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        806..843
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        962..987
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1020..1049
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1056..1088
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1221..1238
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1239..1267
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1368..1385
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1762 AA;  191227 MW;  7A9E9491EF2013E5 CRC64;
     MSPGTPGPTM GRSQGSPMDP MVMKRPQLYG MGTHPHSQPQ QSSPYPGGSY GPPGAQRYPL
     GMQGRAPGAL GGLQYPQQQM PPQYGQQAVS GYCQQGQQPY YNQQPQPSHL PPQAQYLQPA
     AAQSQQRYQP QQDMSQEGYG TRSQPPLAPG KSNHEDLNLI QQERPSSLPD LSGSIDDLPT
     GTEATLSSAV SASGSTSSQG DQSNPAQSPF SPHASPHLSS IPGGPSPSPV GSPVGSNQSR
     SGPISPASIP GFMTGTQRNP QMSQYGPQQT GPSMSPHPSP GGQMHPGISN FQQSNSSGTY
     GPQMSQYGPQ GNYSRTPTYS GVPSASYSGP GPGMGINANN QMHGQGPAQP CGAMPLGRMP
     SAGMQNRPFP GTMSSVTPSS PGMSQQGGPG MGPPMPTVNR KAQEAAAAVM QAAANSAQSR
     QGSFPGMNQS GLVASSSPYS QSMNNNSSLM STQAQPYSMT PTMVNSSTAS MGLADMMSPS
     ESKLSVPLKA DGKEEGVSQP ESKSKDSYGS QGISQPPTPG NLPVPSPMSP SSASISSFHG
     DESDSISSPG WPKTPSSPKS SSSSTTGEKI TKVYELGNEP ERKLWVDRYL TFMEERGSPV
     SSLPAVGKKP LDLFRLYVCV KEIGGLAQVN KNKKWRELAT NLNVGTSSSA ASSLKKQYIQ
     YLFAFECKTE RGEEPPPEVF STGDSKKQPK LQPPSPANSG SLQGPQTPQS TGSNSMAEVP
     GDLKPPTPAS TPHGQMTPMQ SGRSSTVSVH DPFSDVSDSA YPKRNSMTPN APYQQGMGMP
     DMMGRMPYEP NKDPFSGMRK VPGSSEPFMT QGQVPNSGMQ DMYNQSPSGA MSNLGMGQRQ
     QFPYGTSYDR RHEAYGQQYP GQGPPTGQPP YGGHQPGLYP QQPNYKRHMD GMYGPPAKRH
     EGDMYNMQYG SQQQEMYNQY GGSYSGPDRR PIQGQYPYPY NRERMQGPGQ MQPHGIPPQM
     MGGPMQSSSS EGPQQNMWAT RNDMPYPYQS RQGPGGPAQA PPYPGMNRTD DMMVPEQRIN
     HESQWPSHVS QRQPYMSSSA SMQPITRPPQ SSYQTPPSLP NHISRAPSPA SFQRSLESRM
     SPSKSPFLPT MKMQKVMPTV PTSQVTGPPP QPPPIRREIT FPPGSVEASQ PILKQRRKIT
     SKDIVTPEAW RVMMSLKSGL LAESTWALDT INILLYDDST VATFNLSQLS GFLELLVEYF
     RKCLIDIFGI LMEYEVGDPS QKALDHRSGK KDDSQSLEDD SGKEDDDAEC LVEEEEEEEE
     EEEDSEKIES EGKSSPALAA PDASVDPKET PKQASKFDKL PIKIVKKNKL FVVDRSDKLG
     RVQEFSSGLL HWQLGGGDTT EHIQTHFESK MEIPPRRRPP PPLSSTGKKK ELEGKGDSEE
     QPEKSIIATI DDVLSARPGA LPEDTNPGPQ TDSGKFPFGI QQAKSHRNIR LLEDEPRSRD
     ETPLCTIAHW QDSLAKRCIC VSNIVRSLSF VPGNDAEMSK HPGLVLILGK LILLHHEHPE
     RKRAPQTYEK EEDEDKGVAC SKDEWWWDCL EVLRDNTLVT LANISGQLDL SAYTESICLP
     ILDGLLHWMV CPSAEAQDPF PTVGPNSVLS PQRLVLETLC KLSIQDNNVD LILATPPFSR
     QEKFYATLVR YVGDRKNPVC REMSMALLSN LAQGDTLAAR AIAVQKGSIG NLISFLEDGV
     TMAQYQQSQH NLMHMQPPPL EPPSVDMMCR AAKALLAMAR VDENRSEFLL HEGRLLDISI
     SAVLNSLVAS VICDVLFQIG QL
//