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Protein
Submitted name:

Tropomyosin alpha-1 chain

Gene

Tpm1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • structural constituent of cytoskeleton Source: MGI

GO - Biological processi

  • in utero embryonic development Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Tropomyosin alpha-1 chainImported
Gene namesi
Name:Tpm1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:98809. Tpm1.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: MGI
  • muscle thin filament tropomyosin Source: MGI
  • myofibril Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiE9Q452.
PRIDEiE9Q452.

Expressioni

Gene expression databases

BgeeiE9Q452.
ExpressionAtlasiE9Q452. baseline and differential.
GenevisibleiE9Q452. MM.

Structurei

3D structure databases

ProteinModelPortaliE9Q452.
SMRiE9Q452. Positions 1-280.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tropomyosin family.UniRule annotation

Keywords - Domaini

Coiled coilSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00550000074494.
KOiK10373.

Family and domain databases

InterProiIPR000533. Tropomyosin.
[Graphical view]
PfamiPF00261. Tropomyosin. 1 hit.
[Graphical view]
PRINTSiPR00194. TROPOMYOSIN.
PROSITEiPS00326. TROPOMYOSIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q452-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAIKKKMQM LKLDKENALD RAEQAEADKK AAEDRSKQLE DELVSLQKKL
60 70 80 90 100
KGTEDELDKY SEALKDAQEK LELAEKKATD AEADVASLNR RIQLVEEELD
110 120 130 140 150
RAQERLATAL QKLEEAEKAA DESERGMKVI ESRAQKDEEK MEIQEIQLKE
160 170 180 190 200
AKHIAEDADR KYEEVARKLV IIESDLERAE ERAELSEGKC AELEEELKTV
210 220 230 240 250
TNNLKSLEAQ AEKYSQKEDK YEEEIKVLSD KLKEAETRAE FAERSVTKLE
260 270 280
KSIDDLEDQL YHQLEQNRRL TNELKLALNE D
Length:281
Mass (Da):32,495
Last modified:April 5, 2011 - v1
Checksum:iE8CA06AF0B96E230
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC166370 Genomic DNA. No translation available.
RefSeqiNP_001157727.1. NM_001164255.1.
UniGeneiMm.121878.

Genome annotation databases

EnsembliENSMUST00000113693; ENSMUSP00000109323; ENSMUSG00000032366.
GeneIDi22003.
KEGGimmu:22003.
UCSCiuc012gvw.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC166370 Genomic DNA. No translation available.
RefSeqiNP_001157727.1. NM_001164255.1.
UniGeneiMm.121878.

3D structure databases

ProteinModelPortaliE9Q452.
SMRiE9Q452. Positions 1-280.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiE9Q452.
PRIDEiE9Q452.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000113693; ENSMUSP00000109323; ENSMUSG00000032366.
GeneIDi22003.
KEGGimmu:22003.
UCSCiuc012gvw.1. mouse.

Organism-specific databases

CTDi7168.
MGIiMGI:98809. Tpm1.

Phylogenomic databases

GeneTreeiENSGT00550000074494.
KOiK10373.

Miscellaneous databases

ChiTaRSiTpm1. mouse.
NextBioi301732.
SOURCEiSearch...

Gene expression databases

BgeeiE9Q452.
ExpressionAtlasiE9Q452. baseline and differential.
GenevisibleiE9Q452. MM.

Family and domain databases

InterProiIPR000533. Tropomyosin.
[Graphical view]
PfamiPF00261. Tropomyosin. 1 hit.
[Graphical view]
PRINTSiPR00194. TROPOMYOSIN.
PROSITEiPS00326. TROPOMYOSIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q452_MOUSE
AccessioniPrimary (citable) accession number: E9Q452
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 24, 2015
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.