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Protein
Submitted name:

Unconventional myosin-XVIIIa

Gene

Myo18a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Motor protein, MyosinSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Unconventional myosin-XVIIIaImported
Gene namesi
Name:Myo18aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:2667185. Myo18a.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

EPDiE9Q405.
PaxDbiE9Q405.

Expressioni

Gene expression databases

BgeeiE9Q405.
ExpressionAtlasiE9Q405. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000090563.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini74 – 846773Myosin motorInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili910 – 96556Sequence analysisAdd
BLAST
Coiled coili973 – 101442Sequence analysisAdd
BLAST
Coiled coili1036 – 1162127Sequence analysisAdd
BLAST
Coiled coili1170 – 124980Sequence analysisAdd
BLAST
Coiled coili1255 – 130349Sequence analysisAdd
BLAST
Coiled coili1374 – 147198Sequence analysisAdd
BLAST
Coiled coili1478 – 1589112Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.SAAS annotation
Contains IQ domain.SAAS annotation
Contains myosin motor domain.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0161. Eukaryota.
COG5022. LUCA.
GeneTreeiENSGT00840000129849.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
4.10.270.10. 1 hit.
InterProiIPR000048. IQ_motif_EF-hand-BS.
IPR031244. MYO18A.
IPR027401. Myosin-like_IQ_dom.
IPR001609. Myosin_head_motor_dom.
IPR002928. Myosin_tail.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR13140:SF421. PTHR13140:SF421. 4 hits.
PfamiPF00063. Myosin_head. 2 hits.
PF01576. Myosin_tail_1. 1 hit.
[Graphical view]
PRINTSiPR00193. MYOSINHEAVY.
SMARTiSM00015. IQ. 1 hit.
SM00242. MYSc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiPS50096. IQ. 1 hit.
PS51456. MYOSIN_MOTOR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q405-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLAKTEEQIA AEEAWYETEK VWLVHRDGFS LASQLKSEEL SLPEGKARVK
60 70 80 90 100
LDHDGAILDV DEDDIEKANA PSCDRLEDLA SLVYLNESSV LHTLRQRYGA
110 120 130 140 150
SLLHTYAGPS LLVLSTRGAP AVYSEKVMHM FKGCRREDMA PHIYAVAQTA
160 170 180 190 200
YRAMLMSRQD QSIVLLGSSG SGKTTSFQHL VQYLATIAGT SGTKVFSVEK
210 220 230 240 250
WQALSTLLEA FGNSPTIMNG SATRFSQILS LDFDQAGQVA SASIQTMLLE
260 270 280 290 300
KLRVARRPAS EATFNVFYYL LACGDATLRT ELHLNHLAEN NVFGIVPLSK
310 320 330 340 350
PEEKQKAAQQ FSKLQAAMKV LAISPEEQKT CWLILASIYH LGAAGATKAG
360 370 380 390 400
RKQFARHEWA QKAAYLLGCS LEELSSAIFK HQLKGGTLQR STSFRQGPEE
410 420 430 440 450
SGLGEGTKLS ALECLEGMAS GLYSELFTLL ISLVNRALKS SQHSLCSMMI
460 470 480 490 500
VDTPGFQNPE WGGSARGASF EELCHNYAQD RLQRLFHERT FLQELERYKE
510 520 530 540 550
DNIELAFDDL EPVADDSVAA VDQASHLVRS LAHADEARGL LWLLEEEALV
560 570 580 590 600
PGATEDALLD RLFSYYGPQE GDKKGQSPLL RSSKPRHFLL GHSHGTNWVE
610 620 630 640 650
YNVAGWLNYT KQNPATQNAP RLLQDSQKKI ISNLFLGRAG SATVLSGSIA
660 670 680 690 700
GLEGGSQLAL RRATSMRKTF TTGMAAVKKK SLCIQIKLQV DALIDTIKRS
710 720 730 740 750
KMHFVHCFLP VAEGWPGEPR SASSRRVSSS SELDLPPGDP CEAGLLQLDV
760 770 780 790 800
SLLRAQLRGS RLLDAMRMYR QGYPDHMVFS EFRRRFDVLA PHLTKKHGRN
810 820 830 840 850
YIVVDEKRAV EELLESLDLE KSSCCLGLSR VFFRAGTLAR LEEQRDEQTS
860 870 880 890 900
RHLTLFQAAC RGYLARQHFK KRKIQDLAIR CVQKNIKKNK GVKDWPWWKL
910 920 930 940 950
FTTVRPLIQV QLSEEQIRNK DEEIQQLRSK LEKVEKERNE LRLSSDRLET
960 970 980 990 1000
RISELTSELT DERNTGESAS QLLDAETAER LRTEKEMKEL QTQYDALKKQ
1010 1020 1030 1040 1050
MEVMEMEVME ARLIRAAEIN GEVDDDDAGG EWRLKYERAV REVDFTKKRL
1060 1070 1080 1090 1100
QQELEDKMEV EQQSRRQLER RLGDLQADSD ESQRALQQLK KKCQRLTAEL
1110 1120 1130 1140 1150
QDTKLHLEGQ QVRNHELEKK QRRFDSELSQ AHEETQREKL QREKLQREKD
1160 1170 1180 1190 1200
MLLAEAFSLK QQMEEKDLDI AGFTQKVVSL EAELQDISSQ ESKDEASLAK
1210 1220 1230 1240 1250
VKKQLRDLEA KVKDQEEELD EQAGSIQMLE QAKLRLEMEM ERMRQTHSKE
1260 1270 1280 1290 1300
MESRDEEVEE ARQSCQKKLK QMEVQLEEEY EDKQKALREK RELESKLSTL
1310 1320 1330 1340 1350
SDQVNQRDFE SEKRLRKDLK RTKALLADAQ IMLDHLKNNA PSKREIAQLK
1360 1370 1380 1390 1400
NQLEESEFTC AAAVKARKAM EVEMEDLHLQ IDDIAKAKTA LEEQLSRLQR
1410 1420 1430 1440 1450
EKNEIQNRLE EDQEDMNELM KKHKAAVAQA SRDMAQMNDL QAQIEESNKE
1460 1470 1480 1490 1500
KQELQEKLQA LQSQVEFLEQ SMVDKSLVSR QEAKIRELET RLEFEKTQVK
1510 1520 1530 1540 1550
RLENLASRLK ETMEKLTEER DQRAAAENRE KEQNKRLQRQ LRDTKEEMSE
1560 1570 1580 1590 1600
LARKEAEASR KKHELEMDLE SLEAANQSLQ ADLKLAFKRI GDLQAAIEDE
1610 1620 1630 1640 1650
MESDENEDLI NSEGDSDVDS ELEDRVDGVK SWLSKNKGPS KAPSDDGSLK
1660 1670 1680 1690 1700
SSSPTSHWKP LAPDPSDDEH DPVDSISRPR FSHSYLSDSD TEAKLTETSA
Length:1,700
Mass (Da):193,647
Last modified:April 5, 2011 - v1
Checksum:i84AE7A548E624359
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591065 Genomic DNA. No translation available.
RefSeqiNP_001278143.1. NM_001291214.1.
UniGeneiMm.341248.
Mm.476162.

Genome annotation databases

EnsembliENSMUST00000100794; ENSMUSP00000098358; ENSMUSG00000000631.
GeneIDi360013.
UCSCiuc007khj.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591065 Genomic DNA. No translation available.
RefSeqiNP_001278143.1. NM_001291214.1.
UniGeneiMm.341248.
Mm.476162.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000090563.

Proteomic databases

EPDiE9Q405.
PaxDbiE9Q405.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000100794; ENSMUSP00000098358; ENSMUSG00000000631.
GeneIDi360013.
UCSCiuc007khj.2. mouse.

Organism-specific databases

CTDi399687.
MGIiMGI:2667185. Myo18a.

Phylogenomic databases

eggNOGiKOG0161. Eukaryota.
COG5022. LUCA.
GeneTreeiENSGT00840000129849.

Miscellaneous databases

ChiTaRSiMyo18a. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiE9Q405.
ExpressionAtlasiE9Q405. baseline and differential.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
4.10.270.10. 1 hit.
InterProiIPR000048. IQ_motif_EF-hand-BS.
IPR031244. MYO18A.
IPR027401. Myosin-like_IQ_dom.
IPR001609. Myosin_head_motor_dom.
IPR002928. Myosin_tail.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR13140:SF421. PTHR13140:SF421. 4 hits.
PfamiPF00063. Myosin_head. 2 hits.
PF01576. Myosin_tail_1. 1 hit.
[Graphical view]
PRINTSiPR00193. MYOSINHEAVY.
SMARTiSM00015. IQ. 1 hit.
SM00242. MYSc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 3 hits.
PROSITEiPS50096. IQ. 1 hit.
PS51456. MYOSIN_MOTOR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
    Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L.
    Mol. Cell. Proteomics 5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. "Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
    Zhou H., Ye M., Dong J., Han G., Jiang X., Wu R., Zou H.
    J. Proteome Res. 7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  5. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  6. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q405_MOUSE
AccessioniPrimary (citable) accession number: E9Q405
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 8, 2016
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.