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E9Q3Z8

- E9Q3Z8_MOUSE

UniProt

E9Q3Z8 - E9Q3Z8_MOUSE

Protein
Submitted name:

Disks large homolog 4

Gene

Dlg4

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. protein binding Source: MGI

    GO - Biological processi

    1. protein localization to synapse Source: MGI
    2. regulation of long-term neuronal synaptic plasticity Source: MGI
    3. synaptic vesicle maturation Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Disks large homolog 4Imported
    Gene namesi
    Name:Dlg4Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 11

    Organism-specific databases

    MGIiMGI:1277959. Dlg4.

    Subcellular locationi

    GO - Cellular componenti

    1. alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex Source: MGI
    2. cell junction Source: MGI
    3. cerebellar mossy fiber Source: MGI
    4. cytoplasm Source: MGI
    5. dendrite Source: MGI
    6. endoplasmic reticulum Source: MGI
    7. excitatory synapse Source: MGI
    8. extrinsic component of cytoplasmic side of plasma membrane Source: MGI
    9. juxtaparanode region of axon Source: MGI
    10. membrane Source: MGI
    11. neuronal postsynaptic density Source: MGI
    12. neuron projection terminus Source: MGI
    13. neuron spine Source: MGI
    14. plasma membrane Source: MGI
    15. postsynaptic density Source: MGI
    16. synapse Source: MGI
    17. synaptic vesicle Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiE9Q3Z8.
    BgeeiE9Q3Z8.

    Structurei

    3D structure databases

    ProteinModelPortaliE9Q3Z8.
    SMRiE9Q3Z8. Positions 94-165.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 PDZ (DHR) domain.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00660000095130.
    OMAiDIMFSER.

    Family and domain databases

    Gene3Di2.30.42.10. 1 hit.
    InterProiIPR016313. DLG1.
    IPR019590. MAGUK_PEST_N.
    IPR001478. PDZ.
    [Graphical view]
    PANTHERiPTHR23119. PTHR23119. 1 hit.
    PfamiPF10608. MAGUK_N_PEST. 1 hit.
    PF00595. PDZ. 1 hit.
    [Graphical view]
    SMARTiSM00228. PDZ. 1 hit.
    [Graphical view]
    SUPFAMiSSF50156. SSF50156. 1 hit.
    PROSITEiPS50106. PDZ. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    E9Q3Z8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDCLCIVTTK KYRYQDEDTP PLEHSPAHLP NQVNAPELVH VAERNLSHLE    50
    AVHGVVGHAH LSSLKANSPP VIVNTDTLEA PGYELQVNGT EGEMEYEEIT 100
    LERGNSGLGF SIAGGTDNPH IGDDPSIFIT KIIPGGAAAQ DGRLRVNDSI 150
    LFVNEVDVRE VTHSA 165
    Length:165
    Mass (Da):17,811
    Last modified:April 5, 2011 - v1
    Checksum:i94E6663ECB1D8626
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei165 – 1651Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL596185 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000134376; ENSMUSP00000115206; ENSMUSG00000020886.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL596185 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E9Q3Z8.
    SMRi E9Q3Z8. Positions 94-165.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000134376 ; ENSMUSP00000115206 ; ENSMUSG00000020886 .

    Organism-specific databases

    MGIi MGI:1277959. Dlg4.

    Phylogenomic databases

    GeneTreei ENSGT00660000095130.
    OMAi DIMFSER.

    Miscellaneous databases

    ChiTaRSi DLG4. mouse.
    NextBioi 35555055.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9Q3Z8.
    Bgeei E9Q3Z8.

    Family and domain databases

    Gene3Di 2.30.42.10. 1 hit.
    InterProi IPR016313. DLG1.
    IPR019590. MAGUK_PEST_N.
    IPR001478. PDZ.
    [Graphical view ]
    PANTHERi PTHR23119. PTHR23119. 1 hit.
    Pfami PF10608. MAGUK_N_PEST. 1 hit.
    PF00595. PDZ. 1 hit.
    [Graphical view ]
    SMARTi SM00228. PDZ. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50156. SSF50156. 1 hit.
    PROSITEi PS50106. PDZ. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9Q3Z8_MOUSE
    AccessioniPrimary (citable) accession number: E9Q3Z8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3