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Protein
Submitted name:

Hexokinase-3

Gene

Hk3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotation, Transferase
Biological processGlycolysisSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase-3Imported
Gene namesi
Name:Hk3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi

Organism-specific databases

MGIiMGI:2670962 Hk3

PTM / Processingi

Proteomic databases

MaxQBiE9Q3Z4
PeptideAtlasiE9Q3Z4
PRIDEiE9Q3Z4

Expressioni

Gene expression databases

BgeeiENSMUSG00000025877
ExpressionAtlasiE9Q3Z4 baseline and differential
GenevisibleiE9Q3Z4 MM

Structurei

3D structure databases

ProteinModelPortaliE9Q3Z4
SMRiE9Q3Z4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 173Hexokinase_1InterPro annotationAdd BLAST173
Domaini181 – 415Hexokinase_2InterPro annotationAdd BLAST235
Domaini426 – 617Hexokinase_1InterPro annotationAdd BLAST192
Domaini623 – 857Hexokinase_2InterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the hexokinase family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1369 Eukaryota
COG5026 LUCA
GeneTreeiENSGT00390000017159

Family and domain databases

InterProiView protein in InterPro
IPR001312 Hexokinase
IPR019807 Hexokinase_BS
IPR022673 Hexokinase_C
IPR022672 Hexokinase_N
PANTHERiPTHR19443 PTHR19443, 4 hits
PfamiView protein in Pfam
PF00349 Hexokinase_1, 2 hits
PF03727 Hexokinase_2, 2 hits
PROSITEiView protein in PROSITE
PS00378 HEXOKINASE_1, 2 hits
PS51748 HEXOKINASE_2, 2 hits

Sequencei

Sequence statusi: Complete.

E9Q3Z4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQALKGQDS PAPSVRMLPT YVRSTPHGTE QGDFLVLELG ATGASLRVLW
60 70 80 90 100
VTLTGTKECR VEPRSREFVI PQEVILGAGQ QLFDFAARCL SEFLDAYPVE
110 120 130 140 150
NQGLKLGFNF SFPCHQTGLD RSTLISWTKG FRCSGVEGQD VVQLLRDAIQ
160 170 180 190 200
RQGTYRIDVV AMVNDTVGTM MGCELGTRPC EVGLIVDTGT NACYMEEARH
210 220 230 240 250
VAALDEDRGR TCVSIEWGSF YDEDALGPVL TTFDSALDRE SLTPGAQRFE
260 270 280 290 300
KMIGGLYLGE LVRLVLVHLT QHGVLFDGCA SPALLSQGCI LLDHVAEMED
310 320 330 340 350
TATGTARVHT ILQDLGLSPR ASDAELVQYV CVAVCTRAAQ LCAAALAAVL
360 370 380 390 400
SRLQHSREQQ TLQVAVATGG RVFERHPRFL RILKETVTLL APNCDVSFIP
410 420 430 440 450
SVDGGGRGVA MVTAVAARLA AHRRILEETL APFQLTLEQM TVVQAQMREA
460 470 480 490 500
MIRGLQGEAS SLRMLPTYVR ATPDGSERGD FLALDLGGTN FRVLLVRVAE
510 520 530 540 550
GSVQIINQVY SIPECRAQGS GQKLFDHIVD CIVDFQKRQG LSGQSLPLGF
560 570 580 590 600
TFSFPCKQLG LDQGILLNWT KGFNASGCEG QDVVYLLREA IRRRQAVELN
610 620 630 640 650
VVAIVNDTVG TMMSCGYDDP RCEMGLIVGT GTNACYMEEL RNVASVPGDS
660 670 680 690 700
GLMCINMEWG AFGDDGSLGT LSTRFDTSVD QASINPGKQR FEKMISGMYL
710 720 730 740 750
GEIVRHILLH LTNLGVLFRG QKTQCLQARD IFKTKFLSEI ESDSLALRQV
760 770 780 790 800
RAILEDLGLT LTSDDALMVL EVCQAVSRRA AQLCGAGVAA VVEKIRENRG
810 820 830 840 850
LQELTVSVGV DGTLYKLHPH FSKLVSATVR KLAPQCTVTF LQSEDGSGKG
860
AALVTAVACR LTQMAHV
Length:867
Mass (Da):94,231
Last modified:April 5, 2011 - v1
Checksum:i00043A686D3E52DE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154610 Genomic DNA No translation available.
RefSeqiNP_001193321.1, NM_001206392.1
UniGeneiMm.267479

Genome annotation databases

EnsembliENSMUST00000153665; ENSMUSP00000115227; ENSMUSG00000025877
GeneIDi212032

Similar proteinsi

Entry informationi

Entry nameiE9Q3Z4_MOUSE
AccessioniPrimary (citable) accession number: E9Q3Z4
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 25, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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