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E9Q3Z4

- E9Q3Z4_MOUSE

UniProt

E9Q3Z4 - E9Q3Z4_MOUSE

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Protein
Submitted name:

Hexokinase-3

Gene

Hk3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. fructokinase activity Source: RefGenome
  3. glucokinase activity Source: RefGenome
  4. hormone binding Source: Ensembl
  5. mannokinase activity Source: RefGenome

GO - Biological processi

  1. carbohydrate phosphorylation Source: GOC
  2. cellular glucose homeostasis Source: RefGenome
  3. glucose 6-phosphate metabolic process Source: GOC
  4. glycolytic process Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase-3Imported
Gene namesi
Name:Hk3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 13

Organism-specific databases

MGIiMGI:2670962. Hk3.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: RefGenome
  2. mitochondrion Source: MGI
  3. protein complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiE9Q3Z4.
ExpressionAtlasiE9Q3Z4. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9Q3Z4.
SMRiE9Q3Z4. Positions 1-863.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000017159.
KOiK00844.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q3Z4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEQALKGQDS PAPSVRMLPT YVRSTPHGTE QGDFLVLELG ATGASLRVLW
60 70 80 90 100
VTLTGTKECR VEPRSREFVI PQEVILGAGQ QLFDFAARCL SEFLDAYPVE
110 120 130 140 150
NQGLKLGFNF SFPCHQTGLD RSTLISWTKG FRCSGVEGQD VVQLLRDAIQ
160 170 180 190 200
RQGTYRIDVV AMVNDTVGTM MGCELGTRPC EVGLIVDTGT NACYMEEARH
210 220 230 240 250
VAALDEDRGR TCVSIEWGSF YDEDALGPVL TTFDSALDRE SLTPGAQRFE
260 270 280 290 300
KMIGGLYLGE LVRLVLVHLT QHGVLFDGCA SPALLSQGCI LLDHVAEMED
310 320 330 340 350
TATGTARVHT ILQDLGLSPR ASDAELVQYV CVAVCTRAAQ LCAAALAAVL
360 370 380 390 400
SRLQHSREQQ TLQVAVATGG RVFERHPRFL RILKETVTLL APNCDVSFIP
410 420 430 440 450
SVDGGGRGVA MVTAVAARLA AHRRILEETL APFQLTLEQM TVVQAQMREA
460 470 480 490 500
MIRGLQGEAS SLRMLPTYVR ATPDGSERGD FLALDLGGTN FRVLLVRVAE
510 520 530 540 550
GSVQIINQVY SIPECRAQGS GQKLFDHIVD CIVDFQKRQG LSGQSLPLGF
560 570 580 590 600
TFSFPCKQLG LDQGILLNWT KGFNASGCEG QDVVYLLREA IRRRQAVELN
610 620 630 640 650
VVAIVNDTVG TMMSCGYDDP RCEMGLIVGT GTNACYMEEL RNVASVPGDS
660 670 680 690 700
GLMCINMEWG AFGDDGSLGT LSTRFDTSVD QASINPGKQR FEKMISGMYL
710 720 730 740 750
GEIVRHILLH LTNLGVLFRG QKTQCLQARD IFKTKFLSEI ESDSLALRQV
760 770 780 790 800
RAILEDLGLT LTSDDALMVL EVCQAVSRRA AQLCGAGVAA VVEKIRENRG
810 820 830 840 850
LQELTVSVGV DGTLYKLHPH FSKLVSATVR KLAPQCTVTF LQSEDGSGKG
860
AALVTAVACR LTQMAHV
Length:867
Mass (Da):94,231
Last modified:April 5, 2011 - v1
Checksum:i00043A686D3E52DE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC154610 Genomic DNA. No translation available.
RefSeqiNP_001193321.1. NM_001206392.1.
UniGeneiMm.267479.

Genome annotation databases

EnsembliENSMUST00000153665; ENSMUSP00000115227; ENSMUSG00000025877.
GeneIDi212032.
KEGGimmu:212032.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC154610 Genomic DNA. No translation available.
RefSeqi NP_001193321.1. NM_001206392.1.
UniGenei Mm.267479.

3D structure databases

ProteinModelPortali E9Q3Z4.
SMRi E9Q3Z4. Positions 1-863.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000153665 ; ENSMUSP00000115227 ; ENSMUSG00000025877 .
GeneIDi 212032.
KEGGi mmu:212032.

Organism-specific databases

CTDi 3101.
MGIi MGI:2670962. Hk3.

Phylogenomic databases

GeneTreei ENSGT00390000017159.
KOi K00844.

Miscellaneous databases

NextBioi 373427.
SOURCEi Search...

Gene expression databases

Bgeei E9Q3Z4.
ExpressionAtlasi E9Q3Z4. baseline and differential.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
PROSITEi PS00378. HEXOKINASES. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q3Z4_MOUSE
AccessioniPrimary (citable) accession number: E9Q3Z4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: October 29, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3