Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Transporter

Gene

Slc6a9

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • glycine secretion, neurotransmission Source: MGI
  • glycine transport Source: MGI
  • regulation of synaptic transmission, glycinergic Source: GO_Central
Complete GO annotation...

Keywords - Biological processi

SymportUniRule annotationSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
TransporterUniRule annotation
Gene namesi
Name:Slc6a9Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:95760. Slc6a9.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei93 – 11119HelicalSequence analysisAdd
BLAST
Transmembranei123 – 14422HelicalSequence analysisAdd
BLAST
Transmembranei165 – 19228HelicalSequence analysisAdd
BLAST
Transmembranei272 – 29322HelicalSequence analysisAdd
BLAST
Transmembranei305 – 33228HelicalSequence analysisAdd
BLAST
Transmembranei352 – 36918HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: MGI
  • integral component of plasma membrane Source: GO_Central
  • plasma membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiE9Q3Z2.

Expressioni

Gene expression databases

BgeeiE9Q3Z2.
ExpressionAtlasiE9Q3Z2. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000030269.

Structurei

3D structure databases

ProteinModelPortaliE9Q3Z2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiCOG0733. LUCA.
KOG3659. Eukaryota.
GeneTreeiENSGT00760000118857.

Family and domain databases

InterProiIPR000175. Na/ntran_symport.
IPR003028. Na/ntran_symport_glycine_GLY1.
[Graphical view]
PANTHERiPTHR11616. PTHR11616. 1 hit.
PfamiPF00209. SNF. 1 hit.
[Graphical view]
PRINTSiPR01204. GLY1TRNSPORT.
PR00176. NANEUSMPORT.
PROSITEiPS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
PS00754. NA_NEUROTRAN_SYMP_2. 1 hit.
PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

E9Q3Z2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASAQGPVAT PSPEQGFICR PPSHSVTPFP GTTSVSFSQA CPQSLARCPQ
60 70 80 90 100
LWSPVLTHSP ASPAMAQNGA VPSEATKKDQ NLTRGNWGNQ IEFVLTSVGY
110 120 130 140 150
AVGLGNVWRF PYLCYRNGGG AFMFPYFIML IFCGIPLFFM ELSFGQFASQ
160 170 180 190 200
GCLGVWRISP MFKGVGYGMM VVSTYIGIYY NVVICIAFYY FFSSMTHVLP
210 220 230 240 250
WAYCNNPWNT PDCAGVLDAS NLTNGSRPAA LSGNLSHLFN YTLQRTSPSE
260 270 280 290 300
EYWRLYVLKL SDDIGNFGEV RLPLLGCLGV SWVVVFLCLI RGVKSSGKVV
310 320 330 340 350
YFTATFPYVV LTILFVRGVT LEGAFTGIMY YLTPQWDKIL EAKVWGDAAS
360 370
QIFYSLGCAW GGLITMASYN KFH
Length:373
Mass (Da):41,094
Last modified:April 5, 2011 - v1
Checksum:i412B7D3F40EC17E6
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei373 – 3731Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL627128 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000169990; ENSMUSP00000127203; ENSMUSG00000028542.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL627128 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliE9Q3Z2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000030269.

Proteomic databases

PaxDbiE9Q3Z2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000169990; ENSMUSP00000127203; ENSMUSG00000028542.

Organism-specific databases

MGIiMGI:95760. Slc6a9.

Phylogenomic databases

eggNOGiCOG0733. LUCA.
KOG3659. Eukaryota.
GeneTreeiENSGT00760000118857.

Miscellaneous databases

NextBioi35555053.
SOURCEiSearch...

Gene expression databases

BgeeiE9Q3Z2.
ExpressionAtlasiE9Q3Z2. baseline and differential.

Family and domain databases

InterProiIPR000175. Na/ntran_symport.
IPR003028. Na/ntran_symport_glycine_GLY1.
[Graphical view]
PANTHERiPTHR11616. PTHR11616. 1 hit.
PfamiPF00209. SNF. 1 hit.
[Graphical view]
PRINTSiPR01204. GLY1TRNSPORT.
PR00176. NANEUSMPORT.
PROSITEiPS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
PS00754. NA_NEUROTRAN_SYMP_2. 1 hit.
PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q3Z2_MOUSE
AccessioniPrimary (citable) accession number: E9Q3Z2
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: December 9, 2015
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.