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Protein
Submitted name:

Complement receptor type 2

Gene

Cr2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

ReactomeiR-MMU-977606. Regulation of Complement cascade.

Names & Taxonomyi

Protein namesi
Submitted name:
Complement receptor type 2Imported
Gene namesi
Name:Cr2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:88489. Cr2.

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi2 ↔ 45PROSITE-ProRule annotation
Disulfide bondi225 ↔ 252PROSITE-ProRule annotation
Disulfide bondi284 ↔ 311PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PaxDbiE9Q3S5.

Expressioni

Gene expression databases

BgeeiENSMUSG00000094924.
ExpressionAtlasiE9Q3S5. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000044261.

Structurei

3D structure databases

ProteinModelPortaliE9Q3S5.
SMRiE9Q3S5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 60Sushi (CCP/SCR)InterPro annotationAdd BLAST60
Domaini61 – 122Sushi (CCP/SCR)InterPro annotationAdd BLAST62
Domaini123 – 193Sushi (CCP/SCR)InterPro annotationAdd BLAST71
Domaini195 – 254Sushi (CCP/SCR)InterPro annotationAdd BLAST60
Domaini255 – 313Sushi (CCP/SCR)InterPro annotationAdd BLAST59

Keywords - Domaini

SushiPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4297. Eukaryota.
ENOG410XPJ1. LUCA.
GeneTreeiENSGT00760000118803.
TreeFamiTF334137.

Family and domain databases

CDDicd00033. CCP. 5 hits.
InterProiView protein in InterPro
IPR000436. Sushi_SCR_CCP_dom.
PfamiView protein in Pfam
PF00084. Sushi. 5 hits.
SMARTiView protein in SMART
SM00032. CCP. 5 hits.
SUPFAMiSSF57535. SSF57535. 5 hits.
PROSITEiView protein in PROSITE
PS50923. SUSHI. 5 hits.

Sequencei

Sequence statusi: Complete.

E9Q3S5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QCKLLPKYSF AKPSIVSDKS EFAIGTTWEY KCRPGYFRKS FIITCLETSK
60 70 80 90 100
WSDAQQFCKR KPCMNPQEPL HGSVHINTGI EFGSTITYSC NQGYRLIGDS
110 120 130 140 150
SATCIVSDNT VMWDNDMPLC ESIPCESPPA ISNGDFYSSS RDSFFYGMVV
160 170 180 190 200
TYYCHTGKNR EKLFDLVGEK SIYCTSKDNQ VGIWNSPPPQ CIPRVKCPMP
210 220 230 240 250
EIENGLVESG FKHSFFLNDT VIFKCKSGFT MKGSRIAWCQ PNSKWSPPLP
260 270 280 290 300
TCFMGCLPPQ NILHGDYNKK DEFFSVGQKV SYSCNPGYTL IGTNLVECTS
310 320 330 340
LGTWSNTVPT CEVKSCDAIP NHLLHGRVFL PPNLQLGAEV SFVCDLG
Length:347
Mass (Da):38,768
Last modified:October 3, 2012 - v2
Checksum:i717F9FF74A63A86F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC139206 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000043104; ENSMUSP00000044261; ENSMUSG00000026616.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiE9Q3S5_MOUSE
AccessioniPrimary (citable) accession number: E9Q3S5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: October 3, 2012
Last modified: July 5, 2017
This is version 52 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported