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Protein
Submitted name:

Protein Cenpf

Gene

Cenpf

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-2467813. Separation of Sister Chromatids.
R-MMU-2500257. Resolution of Sister Chromatid Cohesion.
R-MMU-5663220. RHO GTPases Activate Formins.
R-MMU-68877. Mitotic Prometaphase.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein CenpfImported
Gene namesi
Name:CenpfImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1313302. Cenpf.

Subcellular locationi

GO - Cellular componenti

  • axoneme Source: MGI
  • centrosome Source: MGI
  • chromosome, centromeric region Source: MGI
  • ciliary basal body Source: MGI
  • ciliary transition fiber Source: MGI
  • condensed chromosome outer kinetochore Source: MGI
  • cytoplasm Source: MGI
  • midbody Source: MGI
  • nuclear envelope Source: MGI
  • nuclear matrix Source: MGI
  • nucleoplasm Source: MGI
  • nucleus Source: MGI
  • pronucleus Source: MGI
  • spindle Source: MGI
  • spindle pole Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiE9Q3P4.
PaxDbiE9Q3P4.
PRIDEiE9Q3P4.

Expressioni

Gene expression databases

BgeeiE9Q3P4.
ExpressionAtlasiE9Q3P4. baseline and differential.
GenevisibleiE9Q3P4. MM.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiE9Q3P4. 12 interactions.
STRINGi10090.ENSMUSP00000129738.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 300300CENP-F_NInterPro annotationAdd
BLAST
Domaini1894 – 2035142CENP-F_leu_zipInterPro annotationAdd
BLAST
Domaini2131 – 2270140CENP-F_leu_zipInterPro annotationAdd
BLAST
Domaini2313 – 2449137CENP-F_leu_zipInterPro annotationAdd
BLAST
Domaini2852 – 289645CENP-F_C_Rb_bdgInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili13 – 131119Sequence analysisAdd
BLAST
Coiled coili159 – 18628Sequence analysisAdd
BLAST
Coiled coili273 – 33563Sequence analysisAdd
BLAST
Coiled coili343 – 39553Sequence analysisAdd
BLAST
Coiled coili425 – 48359Sequence analysisAdd
BLAST
Coiled coili516 – 61297Sequence analysisAdd
BLAST
Coiled coili710 – 73728Sequence analysisAdd
BLAST
Coiled coili831 – 87949Sequence analysisAdd
BLAST
Coiled coili905 – 93935Sequence analysisAdd
BLAST
Coiled coili968 – 100538Sequence analysisAdd
BLAST
Coiled coili1010 – 109081Sequence analysisAdd
BLAST
Coiled coili1131 – 116535Sequence analysisAdd
BLAST
Coiled coili1208 – 125649Sequence analysisAdd
BLAST
Coiled coili1550 – 161364Sequence analysisAdd
BLAST
Coiled coili1825 – 185228Sequence analysisAdd
BLAST
Coiled coili1883 – 191028Sequence analysisAdd
BLAST
Coiled coili1946 – 199752Sequence analysisAdd
BLAST
Coiled coili2023 – 207856Sequence analysisAdd
BLAST
Coiled coili2142 – 219756Sequence analysisAdd
BLAST
Coiled coili2205 – 228581Sequence analysisAdd
BLAST
Coiled coili2324 – 235128Sequence analysisAdd
BLAST
Coiled coili2356 – 2457102Sequence analysisAdd
BLAST
Coiled coili2465 – 249228Sequence analysisAdd
BLAST
Coiled coili2500 – 253435Sequence analysisAdd
BLAST
Coiled coili2559 – 260042Sequence analysisAdd
BLAST
Coiled coili2615 – 270995Sequence analysisAdd
BLAST
Coiled coili2719 – 274628Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IGJF. Eukaryota.
ENOG410XS5F. LUCA.
GeneTreeiENSGT00730000111187.
InParanoidiE9Q3P4.
KOiK11499.
OMAiEIAEYQL.
OrthoDBiEOG7FV3PD.
TreeFamiTF101133.

Family and domain databases

InterProiIPR018302. CenpF/LEK1_Rb-prot-bd.
IPR019513. Centromere_CenpF_leu-rich_rpt.
IPR018463. Centromere_CenpF_N.
[Graphical view]
PfamiPF10490. CENP-F_C_Rb_bdg. 1 hit.
PF10473. CENP-F_leu_zip. 3 hits.
PF10481. CENP-F_N. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q3P4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWALEEWKE GLPSRALQKI QELEGQLEKL KKEKQQRQFQ LDSLEAALQK
60 70 80 90 100
QKQKVEDGKT EGADLKRENQ RLMEICEHLE KSRQKLSHEL QVKESQVNLQ
110 120 130 140 150
ESQLSSCKKQ IEKLEQELKR CKSEFERSQQ VAQSADVSLN PCSTPQKLFA
160 170 180 190 200
TPLTPSSTYE DLKEKYNKEV EERKRLEEEV KALHAKKVSL PVSQATMNHR
210 220 230 240 250
DIARHQASSS VFPWQQENTP SRLSSDALKT PLRRDGSAAH FLGEEVSPNK
260 270 280 290 300
SSMKTGRGDC SSLPGEPHSA QLLHQAKAQN QDLKSKMTEL ELRLQGQEKE
310 320 330 340 350
MRSQVNKCQD LQLQLEKTKV ELIEKERILN KTRDEVVRST AQYDQAAAKC
360 370 380 390 400
TTLEQKLKTL TEELSCHRQN AESAKRSLEQ RIKEKEKELQ EELSRQHQSF
410 420 430 440 450
QALDSEYTQM KTRLTQELQQ VKHLHSTLQL ELEKVTSVKQ QLERNLEEIR
460 470 480 490 500
LKLSRAEQAL QASQVAENEL RRSSEEMKKE NSLIRSQSEQ RTREVCHLEE
510 520 530 540 550
ELGKVKVSLS KSQNFAEEMK AKNTSQEIML RDLQEKLNQQ ENSLTLEKLK
560 570 580 590 600
LALADLERQR NCSQDLLKKR EHHIDQLNNK LNKIEKEFET LLSALELKKK
610 620 630 640 650
ECEELKEEKN QISFWKIDSE KLINQIESEK EILLGKINHL ETSLKTQQVS
660 670 680 690 700
PDSNERIRTL EMERENFTVE IKNLQSMLDS KMVEIKTQKQ AYLELQQKSE
710 720 730 740 750
SSDQKHQKEI ENMCLKANKL TGQVESLECK LQLLSSEVVT KDQQYQDLRM
760 770 780 790 800
EYETLRDLLK SRGSSLVTNE DNQRSSEDNQ RSSEDNQRGS LAFEQQPAVS
810 820 830 840 850
DSFANVMGRK GSINSERSDC SVDGGRSPEH IAILQNRVTS LESSLESQNQ
860 870 880 890 900
MNSDLQMRCE ELLQIKGEVE ENLSKAEQIH QNFVAETNQC ISKLQEDAAV
910 920 930 940 950
HQNIVAETLA TLESKEKELQ LLKEKLEAQQ TEVQKLNKNN CLLEGTLKEL
960 970 980 990 1000
QLLSDTLSSE KKEMNSIISL SKKNIEELTQ ANEALKEVNE ALEQEKMNLL
1010 1020 1030 1040 1050
QKHEKITSCI AEQERSIAEL SDQYKQERLQ LLQRCEETEA VLEDLRGNYK
1060 1070 1080 1090 1100
TAQENNAKLE CMLSECTALC ENRKNELEQL KETFAKEQQE FLTKLAFAEE
1110 1120 1130 1140 1150
QNRKLMLELE IEQQTVRSEI TNTNKHSMSA TDGLRQECLT LNEEQNEQQN
1160 1170 1180 1190 1200
EVSNLTHENE QLMELTQTKH DSYLAVEPVE NSVKATEDEI GKSSSQYQMD
1210 1220 1230 1240 1250
IDTKDISLDS YKAQLVHLEA LVRILEVQLD QSEEENKKLH LELQTIREEL
1260 1270 1280 1290 1300
ETKSSQDPQS QARTGLKDCD TAEEKYVSML QELSASQNEN AHLQCSLQTA
1310 1320 1330 1340 1350
VNKLNELGKM CDVLRVEKLQ LESELNDSRT ECITATSQMT AEVEKLVSEM
1360 1370 1380 1390 1400
KMLNHESALS QNELMKDTSG GEFHDKANHS SVFLTPLDSS NFCEQMTLSS
1410 1420 1430 1440 1450
KEVRVHFAEL QEKFSCLQSE HKILHDQHCE VSSKMSALRS YVDTLKAENS
1460 1470 1480 1490 1500
ALSMSLRTLQ GDLVKEGEPA AEGGHGLPLS FCGADSPSLT NFGETSFYKD
1510 1520 1530 1540 1550
VLEQTGDTCH LSLEGNASAN SCDLDEEFSS SLEEETLTEK ESPPAPGRTV
1560 1570 1580 1590 1600
EGLEVLCQVY LQSLKNLEEK TESQRIMKNK EIEKLEQLLS SERKELSCLR
1610 1620 1630 1640 1650
KQYLSEKEQW QQKLTSVTLE MESKLAEEKQ QTKTLSLELE VARLQLQELD
1660 1670 1680 1690 1700
LSSRSLLGTD LESVVRCQND NYDIKESEVY ISETTEKTPK QDTDQTCDKD
1710 1720 1730 1740 1750
IQQDLGLETS VTESETTRLT GEGCEEQPPK TNCEAPAEDK TQDCSECISE
1760 1770 1780 1790 1800
LCSSSNVLVP MDVLEDQGSI QNLQLQKDTL NENLRLLPEV EDWDKKVESL
1810 1820 1830 1840 1850
LNEIMEADSK LSLQEVQLKM KIATCIQLEK IVKDLRKEKA DLSEKLESLP
1860 1870 1880 1890 1900
CNQEVCLRVE RSEEDLGFNL DMGANELLSK STKDNATNTE DNYKEKFLDM
1910 1920 1930 1940 1950
ERELTRIKSE KANIEHHILS VETNLEVVQA EKLCLERDTE SKQKVIIDLK
1960 1970 1980 1990 2000
EELFTVISER NRLREELDNV SKESKALDQM SKKMKEKIEE LESHQRESLR
2010 2020 2030 2040 2050
HIGAVESEVK DKADLIQTLS FNVGELTKDK AHLQEQLQNL QNDSQELSLA
2060 2070 2080 2090 2100
IGELEIQIGQ LNKEKESLVK ESQNFQIKLT ESECEKQTIS KALEVALKEK
2110 2120 2130 2140 2150
GEFAVQLSSA QEEVHQLRRG IEKLSVRIEA DEKKHLSAVA KLKESQRESD
2160 2170 2180 2190 2200
SLKDTVETLE RELERSEENQ ELAILDSENL KAEVETLKAQ KDEMTKSLRI
2210 2220 2230 2240 2250
FELDLVTVRT ERENLAKQLQ EKQSRVSELD ERCSSLRRLL EEKEQARVQM
2260 2270 2280 2290 2300
EEDSKSAMLM LQMQLKELRE EVAALCNDQE TLKAQEQSLD QPGEEVHHLK
2310 2320 2330 2340 2350
SSIRKLKVHI DADEKKHQNI LEQLKESKHH ADLLKDRVEN LEQELILSEK
2360 2370 2380 2390 2400
NMIFQAEKSK AEIQTLKSEI QRMAQNLQDL QLELISTRSE NENLMKELKK
2410 2420 2430 2440 2450
EQERVSDLET INSSIENLLK DKEQEKVQMK EEAKITVEML QTQLKELNET
2460 2470 2480 2490 2500
VVSLCNDQEV SKTKEQNLGS QVQTLELEKA QLLQDLGEAK NKYIIFQSSV
2510 2520 2530 2540 2550
NALTQEVEAG KQKLEKGEKE IRTLKEQLKS QEQLVCKLAQ VEGEQQLWQK
2560 2570 2580 2590 2600
QKLELRNVTM ALEQKVQVLQ SENNTLQSTY EALQNSHKSL ESELGLIKLE
2610 2620 2630 2640 2650
KVALVERVST ISGKEAELQR ELRDMLQKTT QLSEDYNKEK NRLTEEVEVL
2660 2670 2680 2690 2700
REELQNTKAA HLKSVNQLEK ELQRAQGKIK LMLKSCRQLE GEKEMLQKEL
2710 2720 2730 2740 2750
SQLEAAQQQR AGSLVDSNVD EVMTENKALK ETLEEKVKEA DKYLDKYCSL
2760 2770 2780 2790 2800
LISHEELEKA KEILEIEVAR LKSRQSRQDL QSSPLLNSSI PGPSPNTSVS
2810 2820 2830 2840 2850
EMKSASGQNK ASGKRQRSSG IWEHGKRAAP STAETFSKKS RKSDSKSTRP
2860 2870 2880 2890 2900
AEHEQETEFE PEGLPEVVKK GFADIPTGKT SPYILRRTTM ATRTSPRFAT
2910 2920 2930 2940 2950
QKLVGSSPSL GKENVVESSK PTAGGSRSQK VKVVQESSAD SHTAFQELPA
2960 2970 2980 2990
KSLTASNIPG RNSTESPREG LRAKRAYPAS SPAAGPDPTN NENCRVQ
Length:2,997
Mass (Da):342,472
Last modified:April 5, 2011 - v1
Checksum:i3AEE30F1D554DEC5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140679 Genomic DNA. No translation available.
RefSeqiNP_001074832.2. NM_001081363.2.
UniGeneiMm.129746.

Genome annotation databases

EnsembliENSMUST00000171929; ENSMUSP00000129738; ENSMUSG00000026605.
GeneIDi108000.
KEGGimmu:108000.
UCSCiuc007eao.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC140679 Genomic DNA. No translation available.
RefSeqiNP_001074832.2. NM_001081363.2.
UniGeneiMm.129746.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiE9Q3P4. 12 interactions.
STRINGi10090.ENSMUSP00000129738.

Proteomic databases

MaxQBiE9Q3P4.
PaxDbiE9Q3P4.
PRIDEiE9Q3P4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000171929; ENSMUSP00000129738; ENSMUSG00000026605.
GeneIDi108000.
KEGGimmu:108000.
UCSCiuc007eao.2. mouse.

Organism-specific databases

CTDi1063.
MGIiMGI:1313302. Cenpf.

Phylogenomic databases

eggNOGiENOG410IGJF. Eukaryota.
ENOG410XS5F. LUCA.
GeneTreeiENSGT00730000111187.
InParanoidiE9Q3P4.
KOiK11499.
OMAiEIAEYQL.
OrthoDBiEOG7FV3PD.
TreeFamiTF101133.

Enzyme and pathway databases

ReactomeiR-MMU-2467813. Separation of Sister Chromatids.
R-MMU-2500257. Resolution of Sister Chromatid Cohesion.
R-MMU-5663220. RHO GTPases Activate Formins.
R-MMU-68877. Mitotic Prometaphase.

Miscellaneous databases

ChiTaRSiCenpf. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiE9Q3P4.
ExpressionAtlasiE9Q3P4. baseline and differential.
GenevisibleiE9Q3P4. MM.

Family and domain databases

InterProiIPR018302. CenpF/LEK1_Rb-prot-bd.
IPR019513. Centromere_CenpF_leu-rich_rpt.
IPR018463. Centromere_CenpF_N.
[Graphical view]
PfamiPF10490. CENP-F_C_Rb_bdg. 1 hit.
PF10473. CENP-F_leu_zip. 3 hits.
PF10481. CENP-F_N. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q3P4_MOUSE
AccessioniPrimary (citable) accession number: E9Q3P4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 8, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.