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E9Q3N9

- E9Q3N9_MOUSE

UniProt

E9Q3N9 - E9Q3N9_MOUSE

Protein
Submitted name:

EGF-containing fibulin-like extracellular matrix protein 2

Gene

Efemp2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 32 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro
    2. transmembrane signaling receptor activity Source: InterPro

    GO - Biological processi

    1. blood coagulation Source: InterPro

    Keywords - Ligandi

    CalciumSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    EGF-containing fibulin-like extracellular matrix protein 2Imported
    Gene namesi
    Name:Efemp2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 19

    Organism-specific databases

    MGIiMGI:1891209. Efemp2.

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: InterPro
    2. proteinaceous extracellular matrix Source: MGI

    Keywords - Cellular componenti

    SecretedSAAS annotation

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Expressioni

    Gene expression databases

    ArrayExpressiE9Q3N9.
    BgeeiE9Q3N9.

    Structurei

    3D structure databases

    ProteinModelPortaliE9Q3N9.
    SMRiE9Q3N9. Positions 54-268.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    EGF-like domainUniRule annotationSAAS annotation, RepeatSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00740000115418.

    Family and domain databases

    InterProiIPR026823. cEGF.
    IPR026824. Efemp2.
    IPR000742. EG-like_dom.
    IPR001881. EGF-like_Ca-bd_dom.
    IPR013032. EGF-like_CS.
    IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
    IPR018097. EGF_Ca-bd_CS.
    IPR009030. Growth_fac_rcpt_N_dom.
    IPR001491. Thrombomodulin.
    [Graphical view]
    PANTHERiPTHR24048:SF2. PTHR24048:SF2. 1 hit.
    PfamiPF12662. cEGF. 2 hits.
    PF07645. EGF_CA. 2 hits.
    [Graphical view]
    PRINTSiPR00907. THRMBOMODULN.
    SMARTiSM00181. EGF. 1 hit.
    SM00179. EGF_CA. 3 hits.
    [Graphical view]
    SUPFAMiSSF57184. SSF57184. 3 hits.
    PROSITEiPS00010. ASX_HYDROXYL. 3 hits.
    PS01186. EGF_2. 3 hits.
    PS50026. EGF_3. 3 hits.
    PS01187. EGF_CA. 5 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9Q3N9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLPFASCLPG SLLLWAFLLL LLGAASPQDP EEPDSYTECT DGYEWDADSQ    50
    HCRDVNECLT IPEACKGEMK CINHYGGYLC LPRSAAVISD LHGEGPPPPA 100
    AHAQQPNPCP QGYEPDEQES CVDIDECRYR YCQHRCVNLP GSFRCQCEPG 150
    FQLGPNNRSC VDVNECDMGA PCEQRCFNSY GTFLCRCNQG YELHRDGFSC 200
    SDIDECGYSS YLCQYRCVNE PGRFSCHCPQ GYQLLATRLC QDIDECETGA 250
    HQCSEAQTCV NFHGGYRCVD TNRCVEPYVQ VSDNRCLCPA SNPLCREQPS 300
    SIVHRYMSIT SERSVPADVF QIQATSVYPG AYNAFQIRSG NTQGDFYIRQ 350
    INNVSAMLVL ARPVTGPREY VLDLEMVTMN SLMSYRASSV LRLTVFVGAY 400
    TF 402
    Length:402
    Mass (Da):44,888
    Last modified:April 5, 2011 - v1
    Checksum:i6BB44040C8F7E2A5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC126029 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000167371; ENSMUSP00000129746; ENSMUSG00000024909.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC126029 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E9Q3N9.
    SMRi E9Q3N9. Positions 54-268.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000167371 ; ENSMUSP00000129746 ; ENSMUSG00000024909 .

    Organism-specific databases

    MGIi MGI:1891209. Efemp2.

    Phylogenomic databases

    GeneTreei ENSGT00740000115418.

    Miscellaneous databases

    ChiTaRSi EFEMP2. mouse.
    NextBioi 35555018.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9Q3N9.
    Bgeei E9Q3N9.

    Family and domain databases

    InterProi IPR026823. cEGF.
    IPR026824. Efemp2.
    IPR000742. EG-like_dom.
    IPR001881. EGF-like_Ca-bd_dom.
    IPR013032. EGF-like_CS.
    IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
    IPR018097. EGF_Ca-bd_CS.
    IPR009030. Growth_fac_rcpt_N_dom.
    IPR001491. Thrombomodulin.
    [Graphical view ]
    PANTHERi PTHR24048:SF2. PTHR24048:SF2. 1 hit.
    Pfami PF12662. cEGF. 2 hits.
    PF07645. EGF_CA. 2 hits.
    [Graphical view ]
    PRINTSi PR00907. THRMBOMODULN.
    SMARTi SM00181. EGF. 1 hit.
    SM00179. EGF_CA. 3 hits.
    [Graphical view ]
    SUPFAMi SSF57184. SSF57184. 3 hits.
    PROSITEi PS00010. ASX_HYDROXYL. 3 hits.
    PS01186. EGF_2. 3 hits.
    PS50026. EGF_3. 3 hits.
    PS01187. EGF_CA. 5 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9Q3N9_MOUSE
    AccessioniPrimary (citable) accession number: E9Q3N9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 32 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3