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Protein
Submitted name:

EGF-containing fibulin-like extracellular matrix protein 2

Gene

Efemp2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
EGF-containing fibulin-like extracellular matrix protein 2Imported
Gene namesi
Name:Efemp2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:1891209 Efemp2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_500324440228 – 402Sequence analysisAdd BLAST375

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi166 ↔ 176PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

MaxQBiE9Q3N9
PeptideAtlasiE9Q3N9
PRIDEiE9Q3N9

Expressioni

Gene expression databases

BgeeiENSMUSG00000024909
ExpressionAtlasiE9Q3N9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliE9Q3N9
SMRiE9Q3N9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini123 – 161EGF-likeInterPro annotationAdd BLAST39
Domaini162 – 197EGF-likeInterPro annotationAdd BLAST36
Domaini202 – 241EGF-likeInterPro annotationAdd BLAST40

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000118806

Family and domain databases

InterProiView protein in InterPro
IPR026823 cEGF
IPR026824 Efemp2
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR037287 Fibulin_3/4/5
IPR009030 Growth_fac_rcpt_cys_sf
PANTHERiPTHR44074 PTHR44074, 2 hits
PTHR44074:SF3 PTHR44074:SF3, 2 hits
PfamiView protein in Pfam
PF12662 cEGF, 2 hits
PF07645 EGF_CA, 2 hits
SMARTiView protein in SMART
SM00181 EGF, 4 hits
SM00179 EGF_CA, 5 hits
SUPFAMiSSF57184 SSF57184, 3 hits
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 3 hits
PS01186 EGF_2, 2 hits
PS50026 EGF_3, 3 hits
PS01187 EGF_CA, 2 hits

Sequencei

Sequence statusi: Complete.

E9Q3N9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPFASCLPG SLLLWAFLLL LLGAASPQDP EEPDSYTECT DGYEWDADSQ
60 70 80 90 100
HCRDVNECLT IPEACKGEMK CINHYGGYLC LPRSAAVISD LHGEGPPPPA
110 120 130 140 150
AHAQQPNPCP QGYEPDEQES CVDIDECRYR YCQHRCVNLP GSFRCQCEPG
160 170 180 190 200
FQLGPNNRSC VDVNECDMGA PCEQRCFNSY GTFLCRCNQG YELHRDGFSC
210 220 230 240 250
SDIDECGYSS YLCQYRCVNE PGRFSCHCPQ GYQLLATRLC QDIDECETGA
260 270 280 290 300
HQCSEAQTCV NFHGGYRCVD TNRCVEPYVQ VSDNRCLCPA SNPLCREQPS
310 320 330 340 350
SIVHRYMSIT SERSVPADVF QIQATSVYPG AYNAFQIRSG NTQGDFYIRQ
360 370 380 390 400
INNVSAMLVL ARPVTGPREY VLDLEMVTMN SLMSYRASSV LRLTVFVGAY

TF
Length:402
Mass (Da):44,888
Last modified:April 5, 2011 - v1
Checksum:i6BB44040C8F7E2A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126029 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000167371; ENSMUSP00000129746; ENSMUSG00000024909

Similar proteinsi

Entry informationi

Entry nameiE9Q3N9_MOUSE
AccessioniPrimary (citable) accession number: E9Q3N9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 23, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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