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Protein
Submitted name:

Dynactin subunit 1

Gene

Dctn1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Dynactin subunit 1Imported
Gene namesi
Name:Dctn1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:107745. Dctn1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiE9Q3M3.
PaxDbiE9Q3M3.
PeptideAtlasiE9Q3M3.
PRIDEiE9Q3M3.

Expressioni

Gene expression databases

BgeeiENSMUSG00000031865.
ExpressionAtlasiE9Q3M3. baseline and differential.
GenevisibleiE9Q3M3. MM.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliE9Q3M3.
SMRiE9Q3M3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 73CAP-GlyInterPro annotationAdd BLAST43

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili200 – 335Sequence analysisAdd BLAST136
Coiled coili343 – 366Sequence analysisAdd BLAST24
Coiled coili371 – 523Sequence analysisAdd BLAST153
Coiled coili935 – 1026Sequence analysisAdd BLAST92

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0971. Eukaryota.
COG5244. LUCA.
GeneTreeiENSGT00760000119173.

Family and domain databases

Gene3Di2.30.30.190. 1 hit.
InterProiView protein in InterPro
IPR000938. CAP-Gly_domain.
IPR027663. DCTN1.
IPR022157. Dynactin.
PANTHERiPTHR18916:SF54. PTHR18916:SF54. 1 hit.
PfamiView protein in Pfam
PF01302. CAP_GLY. 1 hit.
PF12455. Dynactin. 1 hit.
SMARTiView protein in SMART
SM01052. CAP_GLY. 1 hit.
SUPFAMiSSF74924. SSF74924. 1 hit.
PROSITEiView protein in PROSITE
PS00845. CAP_GLY_1. 1 hit.
PS50245. CAP_GLY_2. 1 hit.

Sequencei

Sequence statusi: Complete.

E9Q3M3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTEASARPL RVGSRVEVIG KGHRGTVAYV GATLFATGKW VGVILDEAKG
60 70 80 90 100
KNDGTVQGRK YFTCDEGHGI FVRQSQIQVF EDGADTTSPE TPDSSASKVL
110 120 130 140 150
KREGADAAAK TSKLRGLKPK KAPTARKTTT RRPKPTRPAS TGVAGPSSSL
160 170 180 190 200
GPSGSASAGE LSSSEPSTPA QTPLAAPIIP TPALTSPGAA PPLPSPSKEE
210 220 230 240 250
EGLRAQVRDL EEKLETLRLK RSEDKAKLKE LEKHKIQLEQ VQEWKSKMQE
260 270 280 290 300
QQADLQRRLK EARKEAKEAL EAKERYMEEM ADTADAIEMA TLDKEMAEER
310 320 330 340 350
AESLQQEVEA LKERVDELTT DLEILKAEIE EKGSDGAASS YQLKQLEEQN
360 370 380 390 400
ARLKDALVRM RDLSSSEKQE HVKLQKLMEK KNQELEVVRQ QRERLQEELS
410 420 430 440 450
QAESTIDELK EQVDAALGAE EMVEMLTDRN LNLEEKVREL RETVGDLEAM
460 470 480 490 500
NEMNDELQEN ARETELELRE QLDMAGARVR EAQKRVEAAQ ETVADYQQTI
510 520 530 540 550
KKYRQLTAHL QDVNRELTNQ QEASVERQQQ PPPETFDFKI KFAETKAHAK
560 570 580 590 600
AIEMELRQME VAQANRHMSL LTAFMPDSFL RPGGDHDCVL VLLLMPRLIC
610 620 630 640 650
KAELIRKQAQ EKFDLSENCS ERPGLRGAAG EQLSFAAGLV YSLSLLQATL
660 670 680 690 700
HRYEHALSQC SVDVYKKVGS LYPEMSAHER SLDFLIELLH KDQLDETVNV
710 720 730 740 750
EPLTKAIKYY QHLYSIHLAE QPEDSTMQLA DHIKFTQSAL DCMGVEVGRL
760 770 780 790 800
RAFLQGGQEA TDIALLLRDL ETSCSDTRQF CKKIRRRMPG TDAPGIPAAL
810 820 830 840 850
AFGSQVSDTL LDCRKHLTWV VAVLQEVAAA AAQLIAPLAE NEGLPVAALE
860 870 880 890 900
ELAFKASEQI YGSPSSSPYE CLRQSCTILI STMNKLATAM QEGEYDAERP
910 920 930 940 950
PSKPPPVELR AAALRAEITD AEGLGLKLED RETVIKELKK SLKIKGEELS
960 970 980 990 1000
EANVRLSLLE KKLDSAAKDA DERIEKVQTR LDETQTLLRK KEKDFEETMD
1010 1020 1030 1040 1050
ALQADIDQLE AEKAELKQRL NSQSKRTIEG LRGPPPSGIA TLVSGIAGEE
1060 1070 1080 1090 1100
PQRGGAPGQA PGALPGPGLV KDSPLLLQQI SAMRLHISQL QHENSILRGA
1110 1120 1130 1140 1150
QMKASLAALP PLHVAKLSLP PHEGPGGNLV AGALYRKTSQ LLEKLNQLST
1160 1170 1180 1190 1200
HTHVVDITRS SPAAKSPSAQ LMEQVAQLKS LSDTIEKLKD EVLKETVTQR
1210 1220 1230 1240 1250
PGATVPTDFA TFPSSAFLRA KEEQQDDTVY MGKVTFSCAA GLGQRHRLVL
1260
TQEQLHQLHS RLIS
Length:1,264
Mass (Da):139,762
Last modified:April 5, 2011 - v1
Checksum:i99C763496C2F193E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC160400 Genomic DNA. No translation available.
RefSeqiNP_001185795.1. NM_001198866.1.
XP_006505551.1. XM_006505488.2.
XP_017176867.1. XM_017321378.1.
UniGeneiMm.6919.

Genome annotation databases

EnsembliENSMUST00000113913; ENSMUSP00000109546; ENSMUSG00000031865.
GeneIDi13191.

Similar proteinsi

Entry informationi

Entry nameiE9Q3M3_MOUSE
AccessioniPrimary (citable) accession number: E9Q3M3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: August 30, 2017
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported