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Protein
Submitted name:

DNA polymerase iota

Gene

Poli

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-5656121. Translesion synthesis by POLI.
R-MMU-5656169. Termination of translesion DNA synthesis.

Names & Taxonomyi

Protein namesi
Submitted name:
DNA polymerase iotaImported
Gene namesi
Name:PoliImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:1347081. Poli.

PTM / Processingi

Proteomic databases

MaxQBiE9Q3H9.
PaxDbiE9Q3H9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000038425.
ExpressionAtlasiE9Q3H9. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9Q3H9.
SMRiE9Q3H9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 177UmuCInterPro annotationAdd BLAST177

Phylogenomic databases

eggNOGiKOG2095. Eukaryota.
COG0389. LUCA.
GeneTreeiENSGT00530000062942.

Family and domain databases

Gene3Di3.30.1490.100. 1 hit.
InterProiView protein in InterPro
IPR017061. DNA_pol_eta/kappa/iota/IV.
IPR017961. DNA_pol_Y-fam_little_finger.
IPR024728. PolY_HhH_motif.
IPR001126. UmuC.
PfamiView protein in Pfam
PF00817. IMS. 1 hit.
PF11799. IMS_C. 1 hit.
PF11798. IMS_HHH. 1 hit.
PIRSFiPIRSF036603. DPol_eta. 2 hits.
SUPFAMiSSF100879. SSF100879. 1 hit.
PROSITEiView protein in PROSITE
PS50173. UMUC. 1 hit.

Sequencei

Sequence statusi: Complete.

E9Q3H9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISNPELKDR PLGVQQKYLV VTCNYEARKL GVRKLMNVRD AKEKCPQLVL
60 70 80 90 100
VNGEDLSRYR EMSYKVTEMV EKRLQQLPSE EVPSVTVFGH VYNNQSVNLH
110 120 130 140 150
NIMHRRLVVG SQIAAEMREA MYNQLGLTGC AGVAPNKLLA KLVSGVFKPN
160 170 180 190 200
QQTVLLPESC QHLIHSLNHI KEIPGIGYKT AKRLEVLGIN SVHDLQTFPI
210 220 230 240 250
KTLEKELGIA IAQRIQQLSF GEDKSPVTPS GPPQSFSEED TFKKCSSEVE
260 270 280 290 300
AKAKIEELLS SLLTRVCQDG RKPHTVRLVI RRYSDKHCNR ESRQCPIPSH
310 320 330 340 350
VIQKLGTGNH DSMPPLIDIL MKLFRNMVNV KMPFHLTLMS VCFCNLKALS
360 370 380 390 400
SAKKGPMDCY LTSLSTPAYT DKRAFKVKDT HTEDSHKEKE ANWDCLPSRR
410 420 430 440 450
IESTGTGESP LDATCFPKEK DTSDLPLQAL PEGVDQEVFK QLPADIQEEI
460 470 480 490 500
LSGKSRENLK GKGSLSCPLH ASRGVLSFFS TKQMQASRLS PRDTALPSKR
510 520 530 540 550
VSAASPCEPG TSGLSPGSTS HPSCGKDCSY YIDSQLKDEQ TSQGPTESQG
560 570 580 590 600
CQFSSTNPAV SGFHSFPNLQ TEQLFSTHRT VDSHKQTATA SHQGLESHQG
610 620 630 640 650
LESRELDSAE EKLPFPPDID PQVFYELPEE VQKELMAEWE RAGAARPSAH

R
Length:651
Mass (Da):72,428
Last modified:April 5, 2011 - v1
Checksum:i0CC74AEC2E0CE734
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC134831 Genomic DNA. No translation available.
RefSeqiNP_001276445.1. NM_001289516.1.
UniGeneiMm.244352.

Genome annotation databases

EnsembliENSMUST00000159389; ENSMUSP00000123964; ENSMUSG00000038425.
GeneIDi26447.
UCSCiuc008foi.3. mouse.

Similar proteinsi

Entry informationi

Entry nameiE9Q3H9_MOUSE
AccessioniPrimary (citable) accession number: E9Q3H9
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: August 30, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported