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Protein
Submitted name:

DNA polymerase iota

Gene

Poli

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-5656121. Translesion synthesis by POLI.
R-MMU-5656169. Termination of translesion DNA synthesis.

Names & Taxonomyi

Protein namesi
Submitted name:
DNA polymerase iotaImported
Gene namesi
Name:PoliImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:1347081. Poli.

PTM / Processingi

Proteomic databases

PaxDbiE9Q3H9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000038425.
ExpressionAtlasiE9Q3H9. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000112563.

Structurei

3D structure databases

ProteinModelPortaliE9Q3H9.
SMRiE9Q3H9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 177UmuCInterPro annotationAdd BLAST177

Phylogenomic databases

eggNOGiKOG2095. Eukaryota.
COG0389. LUCA.
GeneTreeiENSGT00530000062942.

Family and domain databases

Gene3Di3.30.1490.100. 1 hit.
InterProiIPR017961. DNA_pol_Y-fam_little_finger.
IPR024728. PolY_HhH_motif.
IPR001126. UmuC.
[Graphical view]
PfamiPF00817. IMS. 1 hit.
PF11799. IMS_C. 1 hit.
PF11798. IMS_HHH. 1 hit.
[Graphical view]
SUPFAMiSSF100879. SSF100879. 1 hit.
PROSITEiPS50173. UMUC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q3H9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISNPELKDR PLGVQQKYLV VTCNYEARKL GVRKLMNVRD AKEKCPQLVL
60 70 80 90 100
VNGEDLSRYR EMSYKVTEMV EKRLQQLPSE EVPSVTVFGH VYNNQSVNLH
110 120 130 140 150
NIMHRRLVVG SQIAAEMREA MYNQLGLTGC AGVAPNKLLA KLVSGVFKPN
160 170 180 190 200
QQTVLLPESC QHLIHSLNHI KEIPGIGYKT AKRLEVLGIN SVHDLQTFPI
210 220 230 240 250
KTLEKELGIA IAQRIQQLSF GEDKSPVTPS GPPQSFSEED TFKKCSSEVE
260 270 280 290 300
AKAKIEELLS SLLTRVCQDG RKPHTVRLVI RRYSDKHCNR ESRQCPIPSH
310 320 330 340 350
VIQKLGTGNH DSMPPLIDIL MKLFRNMVNV KMPFHLTLMS VCFCNLKALS
360 370 380 390 400
SAKKGPMDCY LTSLSTPAYT DKRAFKVKDT HTEDSHKEKE ANWDCLPSRR
410 420 430 440 450
IESTGTGESP LDATCFPKEK DTSDLPLQAL PEGVDQEVFK QLPADIQEEI
460 470 480 490 500
LSGKSRENLK GKGSLSCPLH ASRGVLSFFS TKQMQASRLS PRDTALPSKR
510 520 530 540 550
VSAASPCEPG TSGLSPGSTS HPSCGKDCSY YIDSQLKDEQ TSQGPTESQG
560 570 580 590 600
CQFSSTNPAV SGFHSFPNLQ TEQLFSTHRT VDSHKQTATA SHQGLESHQG
610 620 630 640 650
LESRELDSAE EKLPFPPDID PQVFYELPEE VQKELMAEWE RAGAARPSAH

R
Length:651
Mass (Da):72,428
Last modified:April 5, 2011 - v1
Checksum:i0CC74AEC2E0CE734
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC134831 Genomic DNA. No translation available.
RefSeqiNP_001276445.1. NM_001289516.1.
UniGeneiMm.244352.

Genome annotation databases

EnsembliENSMUST00000159389; ENSMUSP00000123964; ENSMUSG00000038425.
GeneIDi26447.
UCSCiuc008foi.3. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC134831 Genomic DNA. No translation available.
RefSeqiNP_001276445.1. NM_001289516.1.
UniGeneiMm.244352.

3D structure databases

ProteinModelPortaliE9Q3H9.
SMRiE9Q3H9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000112563.

Proteomic databases

PaxDbiE9Q3H9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000159389; ENSMUSP00000123964; ENSMUSG00000038425.
GeneIDi26447.
UCSCiuc008foi.3. mouse.

Organism-specific databases

CTDi11201.
MGIiMGI:1347081. Poli.

Phylogenomic databases

eggNOGiKOG2095. Eukaryota.
COG0389. LUCA.
GeneTreeiENSGT00530000062942.

Enzyme and pathway databases

ReactomeiR-MMU-5656121. Translesion synthesis by POLI.
R-MMU-5656169. Termination of translesion DNA synthesis.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000038425.
ExpressionAtlasiE9Q3H9. baseline and differential.

Family and domain databases

Gene3Di3.30.1490.100. 1 hit.
InterProiIPR017961. DNA_pol_Y-fam_little_finger.
IPR024728. PolY_HhH_motif.
IPR001126. UmuC.
[Graphical view]
PfamiPF00817. IMS. 1 hit.
PF11799. IMS_C. 1 hit.
PF11798. IMS_HHH. 1 hit.
[Graphical view]
SUPFAMiSSF100879. SSF100879. 1 hit.
PROSITEiPS50173. UMUC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q3H9_MOUSE
AccessioniPrimary (citable) accession number: E9Q3H9
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 2, 2016
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.