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E9Q3G8

- E9Q3G8_MOUSE

UniProt

E9Q3G8 - E9Q3G8_MOUSE

Protein
Submitted name:

Protein Nup153

Gene

Nup153

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 33 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. nucleocytoplasmic transporter activity Source: Ensembl
    2. structural constituent of nuclear pore Source: Ensembl
    3. zinc ion binding Source: InterPro

    GO - Biological processi

    1. negative regulation of RNA export from nucleus Source: Ensembl
    2. nuclear pore complex assembly Source: Ensembl

    Enzyme and pathway databases

    ReactomeiREACT_196650. Nuclear Pore Complex (NPC) Disassembly.
    REACT_204192. Regulation of Glucokinase by Glucokinase Regulatory Protein.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein Nup153Imported
    Gene namesi
    Name:Nup153Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 13

    Organism-specific databases

    MGIiMGI:2385621. Nup153.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl
    2. nuclear inclusion body Source: Ensembl
    3. nuclear membrane Source: Ensembl
    4. nuclear periphery Source: Ensembl
    5. nuclear pore nuclear basket Source: Ensembl
    6. nucleolus Source: Ensembl

    PTM / Processingi

    Proteomic databases

    MaxQBiE9Q3G8.
    PRIDEiE9Q3G8.

    Expressioni

    Gene expression databases

    ArrayExpressiE9Q3G8.
    BgeeiE9Q3G8.

    Structurei

    3D structure databases

    ProteinModelPortaliE9Q3G8.
    SMRiE9Q3G8. Positions 657-682, 719-745, 787-813, 844-869.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00700000104544.
    KOiK14296.
    OMAiSKKPAFN.
    OrthoDBiEOG73JKTK.
    TreeFamiTF323517.

    Family and domain databases

    InterProiIPR013913. Nucleoporin_Nup153.
    IPR018892. Retro-transposon_transp_CS.
    IPR001876. Znf_RanBP2.
    [Graphical view]
    PfamiPF08604. Nup153. 1 hit.
    PF10599. Nup_retrotrp_bd. 1 hit.
    PF00641. zf-RanBP. 4 hits.
    [Graphical view]
    SMARTiSM00547. ZnF_RBZ. 4 hits.
    [Graphical view]
    PROSITEiPS01358. ZF_RANBP2_1. 4 hits.
    PS50199. ZF_RANBP2_2. 4 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9Q3G8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASEAGGIGG GGGGGKIRTR RCHQGPVKPY QQGRPQHQGI LSRVTESVKN     50
    IVPGWLQRYF NKSENACSCS PDADEVPPWP ENREDEHAIY ADENTNTDDG 100
    RITPDPAGSN TEEPSTTSTA SNYPDVLTRP SLHRSHLNFS VLESPALHCQ 150
    PSTSSAFPIG SSGFSLVKEI KDSTSQHDDD NISTTSGFSS RASEKDIAVS 200
    KNTSLPPLWS PEAERSHSLS QHTAISSKKP AFNLSAFGTL STSLGNSSIL 250
    KTSQLGDSPF YPGKTTYGGA AAAVRQNKVR STPYQAPVRR QMKAKQLNAQ 300
    SYGVTSSTAR RILQSLEKMS SPLADAKRIP SAVSSPLNSP LDRSGIDNTV 350
    FQAKKEKVDS QYPPVQRLMT PKPVSIATNR TVYFKPSLTP SGDLRKTNQR 400
    IDKKNSTVDE KSISRQNREQ ESGFSYPNFS IPAANGLSSG VGGGGGKMRR 450
    ERTHFVAPKP PENEEVEAPL LPQISLPISS SSLPTFSFSS PVTSASPSPV 500
    SSSQPLPNKV QMTSLGSTGS PVFTFSSPIV KSTQAAVLPP ASIGFTFSVP 550
    LAKTEFSGSN SSSETVLSSS AQDITAVNSS SYKKRSAPCE DPFTPAKILR 600
    EGSVLDILKT PGFASPKVDS PALQPTTTSS IVYTRPAIST FSSSGIEYGE 650
    SLKAGSSWQC DTCLLQNKVT DNKCIACQAA KLPLKETAKQ TGTGTPSKSD 700
    KPASTSGTGF GDKFKPAIGT WDCDTCLVQN KPEAVKCVAC ETPKPGTGVK 750
    RALTLTVASE SPVTASSSTT VTTGTLGFGD KFKRPVGSWE CPVCCVCNKA 800
    EDNRCVSCTS EKPGLVSASS SSPAPVSLSS GGCLGLDKFK KPEGSWDCEV 850
    CLVQNKADSA KCIACESAKP GTKSEFKGFG TSSSLNPAPS AFKFGIPSSS 900
    SGLSQTLTST GNFKFGDQGG FKLGTSSDSG STNTMNTNFK FSKPTGDFKF 950
    GVLSDSKPEE VKNDNKNDNF QFGSSSGLTN PASSAPFQFG VSTLGQQEKK 1000
    EELPKSSPAG FSFGAGVNNP PNAAIDTTAT SENKSGFNFG TLDTKSVSVT 1050
    PFTYKTTEAK KEDAPATKGG FTFGKVGSSS LPSSSMFVLG RTEEKQQEPV 1100
    TSTSLVFGKK ADSEEPKCQP VFSFGNSEQT KDESSKPTFS FSVAKPSGKE 1150
    SEQLAKATFA FGNQTNTTTD QGAAKPVFSF LNSSSSSSSA PATSSSGGIF 1200
    GSSTSSSNPP VAAFVFGQAS NPVSSSAFGN AAESSTSQSL LFPQESEPAT 1250
    TSSTAPAASP FVFGTGASSN SVSSGFTFGA TTTSSSSGSS FVFGTGHSAP 1300
    SASPAFGANQ TPTFGQSQGA SQPNPPSFGS ISSSTALFSA GSQPVPPPIF 1350
    GTVSSSSQPP VFGQQPSQSA FGSGTANASS VFQFGSSTTN FNFTNNNPSG 1400
    VFTFGASPST PAASAQPSGS GVFSFSQSPA SFTVGSNGKN MFSSSGTSVS 1450
    GRKIKTAVRR KK 1462
    Length:1,462
    Mass (Da):152,008
    Last modified:April 5, 2011 - v1
    Checksum:i1A6FC0CD8AA2C3FC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC124598 Genomic DNA. No translation available.
    RefSeqiNP_786925.2. NM_175749.2.
    UniGeneiMm.255398.
    Mm.445069.

    Genome annotation databases

    EnsembliENSMUST00000021803; ENSMUSP00000021803; ENSMUSG00000021374.
    GeneIDi218210.
    KEGGimmu:218210.
    UCSCiuc007qhj.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC124598 Genomic DNA. No translation available.
    RefSeqi NP_786925.2. NM_175749.2.
    UniGenei Mm.255398.
    Mm.445069.

    3D structure databases

    ProteinModelPortali E9Q3G8.
    SMRi E9Q3G8. Positions 657-682, 719-745, 787-813, 844-869.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    MaxQBi E9Q3G8.
    PRIDEi E9Q3G8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000021803 ; ENSMUSP00000021803 ; ENSMUSG00000021374 .
    GeneIDi 218210.
    KEGGi mmu:218210.
    UCSCi uc007qhj.2. mouse.

    Organism-specific databases

    CTDi 9972.
    MGIi MGI:2385621. Nup153.

    Phylogenomic databases

    GeneTreei ENSGT00700000104544.
    KOi K14296.
    OMAi SKKPAFN.
    OrthoDBi EOG73JKTK.
    TreeFami TF323517.

    Enzyme and pathway databases

    Reactomei REACT_196650. Nuclear Pore Complex (NPC) Disassembly.
    REACT_204192. Regulation of Glucokinase by Glucokinase Regulatory Protein.

    Miscellaneous databases

    NextBioi 376192.
    PROi E9Q3G8.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9Q3G8.
    Bgeei E9Q3G8.

    Family and domain databases

    InterProi IPR013913. Nucleoporin_Nup153.
    IPR018892. Retro-transposon_transp_CS.
    IPR001876. Znf_RanBP2.
    [Graphical view ]
    Pfami PF08604. Nup153. 1 hit.
    PF10599. Nup_retrotrp_bd. 1 hit.
    PF00641. zf-RanBP. 4 hits.
    [Graphical view ]
    SMARTi SM00547. ZnF_RBZ. 4 hits.
    [Graphical view ]
    PROSITEi PS01358. ZF_RANBP2_1. 4 hits.
    PS50199. ZF_RANBP2_2. 4 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
      Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    4. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.
    5. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
      Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiE9Q3G8_MOUSE
    AccessioniPrimary (citable) accession number: E9Q3G8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 33 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3