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E9Q3G8

- E9Q3G8_MOUSE

UniProt

E9Q3G8 - E9Q3G8_MOUSE

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Protein
Submitted name:

Protein Nup153

Gene

Nup153

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. nucleocytoplasmic transporter activity Source: Ensembl
  2. structural constituent of nuclear pore Source: Ensembl
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. negative regulation of RNA export from nucleus Source: Ensembl
  2. nuclear pore complex assembly Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_196650. Nuclear Pore Complex (NPC) Disassembly.
REACT_204192. Regulation of Glucokinase by Glucokinase Regulatory Protein.
REACT_270446. Transcriptional regulation by small RNAs.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Nup153Imported
Gene namesi
Name:Nup153Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 13

Organism-specific databases

MGIiMGI:2385621. Nup153.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. nuclear inclusion body Source: Ensembl
  3. nuclear membrane Source: Ensembl
  4. nuclear periphery Source: Ensembl
  5. nuclear pore nuclear basket Source: Ensembl
  6. nucleolus Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiE9Q3G8.
PRIDEiE9Q3G8.

Expressioni

Gene expression databases

BgeeiE9Q3G8.
ExpressionAtlasiE9Q3G8. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliE9Q3G8.
SMRiE9Q3G8. Positions 657-682, 719-745, 787-813, 844-869.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00700000104544.
InParanoidiE9Q3G8.
KOiK14296.
OMAiSKKPAFN.
OrthoDBiEOG73JKTK.
TreeFamiTF323517.

Family and domain databases

InterProiIPR013913. Nucleoporin_Nup153.
IPR018892. Retro-transposon_transp_CS.
IPR001876. Znf_RanBP2.
[Graphical view]
PfamiPF08604. Nup153. 1 hit.
PF10599. Nup_retrotrp_bd. 1 hit.
PF00641. zf-RanBP. 4 hits.
[Graphical view]
SMARTiSM00547. ZnF_RBZ. 4 hits.
[Graphical view]
PROSITEiPS01358. ZF_RANBP2_1. 4 hits.
PS50199. ZF_RANBP2_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q3G8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASEAGGIGG GGGGGKIRTR RCHQGPVKPY QQGRPQHQGI LSRVTESVKN
60 70 80 90 100
IVPGWLQRYF NKSENACSCS PDADEVPPWP ENREDEHAIY ADENTNTDDG
110 120 130 140 150
RITPDPAGSN TEEPSTTSTA SNYPDVLTRP SLHRSHLNFS VLESPALHCQ
160 170 180 190 200
PSTSSAFPIG SSGFSLVKEI KDSTSQHDDD NISTTSGFSS RASEKDIAVS
210 220 230 240 250
KNTSLPPLWS PEAERSHSLS QHTAISSKKP AFNLSAFGTL STSLGNSSIL
260 270 280 290 300
KTSQLGDSPF YPGKTTYGGA AAAVRQNKVR STPYQAPVRR QMKAKQLNAQ
310 320 330 340 350
SYGVTSSTAR RILQSLEKMS SPLADAKRIP SAVSSPLNSP LDRSGIDNTV
360 370 380 390 400
FQAKKEKVDS QYPPVQRLMT PKPVSIATNR TVYFKPSLTP SGDLRKTNQR
410 420 430 440 450
IDKKNSTVDE KSISRQNREQ ESGFSYPNFS IPAANGLSSG VGGGGGKMRR
460 470 480 490 500
ERTHFVAPKP PENEEVEAPL LPQISLPISS SSLPTFSFSS PVTSASPSPV
510 520 530 540 550
SSSQPLPNKV QMTSLGSTGS PVFTFSSPIV KSTQAAVLPP ASIGFTFSVP
560 570 580 590 600
LAKTEFSGSN SSSETVLSSS AQDITAVNSS SYKKRSAPCE DPFTPAKILR
610 620 630 640 650
EGSVLDILKT PGFASPKVDS PALQPTTTSS IVYTRPAIST FSSSGIEYGE
660 670 680 690 700
SLKAGSSWQC DTCLLQNKVT DNKCIACQAA KLPLKETAKQ TGTGTPSKSD
710 720 730 740 750
KPASTSGTGF GDKFKPAIGT WDCDTCLVQN KPEAVKCVAC ETPKPGTGVK
760 770 780 790 800
RALTLTVASE SPVTASSSTT VTTGTLGFGD KFKRPVGSWE CPVCCVCNKA
810 820 830 840 850
EDNRCVSCTS EKPGLVSASS SSPAPVSLSS GGCLGLDKFK KPEGSWDCEV
860 870 880 890 900
CLVQNKADSA KCIACESAKP GTKSEFKGFG TSSSLNPAPS AFKFGIPSSS
910 920 930 940 950
SGLSQTLTST GNFKFGDQGG FKLGTSSDSG STNTMNTNFK FSKPTGDFKF
960 970 980 990 1000
GVLSDSKPEE VKNDNKNDNF QFGSSSGLTN PASSAPFQFG VSTLGQQEKK
1010 1020 1030 1040 1050
EELPKSSPAG FSFGAGVNNP PNAAIDTTAT SENKSGFNFG TLDTKSVSVT
1060 1070 1080 1090 1100
PFTYKTTEAK KEDAPATKGG FTFGKVGSSS LPSSSMFVLG RTEEKQQEPV
1110 1120 1130 1140 1150
TSTSLVFGKK ADSEEPKCQP VFSFGNSEQT KDESSKPTFS FSVAKPSGKE
1160 1170 1180 1190 1200
SEQLAKATFA FGNQTNTTTD QGAAKPVFSF LNSSSSSSSA PATSSSGGIF
1210 1220 1230 1240 1250
GSSTSSSNPP VAAFVFGQAS NPVSSSAFGN AAESSTSQSL LFPQESEPAT
1260 1270 1280 1290 1300
TSSTAPAASP FVFGTGASSN SVSSGFTFGA TTTSSSSGSS FVFGTGHSAP
1310 1320 1330 1340 1350
SASPAFGANQ TPTFGQSQGA SQPNPPSFGS ISSSTALFSA GSQPVPPPIF
1360 1370 1380 1390 1400
GTVSSSSQPP VFGQQPSQSA FGSGTANASS VFQFGSSTTN FNFTNNNPSG
1410 1420 1430 1440 1450
VFTFGASPST PAASAQPSGS GVFSFSQSPA SFTVGSNGKN MFSSSGTSVS
1460
GRKIKTAVRR KK
Length:1,462
Mass (Da):152,008
Last modified:April 5, 2011 - v1
Checksum:i1A6FC0CD8AA2C3FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124598 Genomic DNA. No translation available.
RefSeqiNP_786925.2. NM_175749.2.
UniGeneiMm.255398.
Mm.445069.

Genome annotation databases

EnsembliENSMUST00000021803; ENSMUSP00000021803; ENSMUSG00000021374.
GeneIDi218210.
KEGGimmu:218210.
UCSCiuc007qhj.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124598 Genomic DNA. No translation available.
RefSeqi NP_786925.2. NM_175749.2.
UniGenei Mm.255398.
Mm.445069.

3D structure databases

ProteinModelPortali E9Q3G8.
SMRi E9Q3G8. Positions 657-682, 719-745, 787-813, 844-869.
ModBasei Search...
MobiDBi Search...

Proteomic databases

MaxQBi E9Q3G8.
PRIDEi E9Q3G8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000021803 ; ENSMUSP00000021803 ; ENSMUSG00000021374 .
GeneIDi 218210.
KEGGi mmu:218210.
UCSCi uc007qhj.2. mouse.

Organism-specific databases

CTDi 9972.
MGIi MGI:2385621. Nup153.

Phylogenomic databases

GeneTreei ENSGT00700000104544.
InParanoidi E9Q3G8.
KOi K14296.
OMAi SKKPAFN.
OrthoDBi EOG73JKTK.
TreeFami TF323517.

Enzyme and pathway databases

Reactomei REACT_196650. Nuclear Pore Complex (NPC) Disassembly.
REACT_204192. Regulation of Glucokinase by Glucokinase Regulatory Protein.
REACT_270446. Transcriptional regulation by small RNAs.

Miscellaneous databases

NextBioi 376192.
PROi E9Q3G8.
SOURCEi Search...

Gene expression databases

Bgeei E9Q3G8.
ExpressionAtlasi E9Q3G8. baseline and differential.

Family and domain databases

InterProi IPR013913. Nucleoporin_Nup153.
IPR018892. Retro-transposon_transp_CS.
IPR001876. Znf_RanBP2.
[Graphical view ]
Pfami PF08604. Nup153. 1 hit.
PF10599. Nup_retrotrp_bd. 1 hit.
PF00641. zf-RanBP. 4 hits.
[Graphical view ]
SMARTi SM00547. ZnF_RBZ. 4 hits.
[Graphical view ]
PROSITEi PS01358. ZF_RANBP2_1. 4 hits.
PS50199. ZF_RANBP2_2. 4 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.
  5. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
    Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
    Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiE9Q3G8_MOUSE
AccessioniPrimary (citable) accession number: E9Q3G8
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: November 26, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3