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E9Q3E3 (E9Q3E3_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length307 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification] RuleBase RU000687

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000103372

Ontologies

Keywords
   Biological processIon transport
Transport
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix SAAS SAAS018000
   Molecular functionIon channel RuleBase RU000687 SAAS SAAS006201
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processacrosome reaction

Inferred from mutant phenotype PubMed 11076688. Source: MGI

adult walking behavior

Inferred from mutant phenotype PubMed 4323808. Source: MGI

chloride transmembrane transport

Inferred from mutant phenotype PubMed 12809985PubMed 16672662. Source: GOC

neuromuscular process

Inferred from mutant phenotype PubMed 10651857PubMed 8635460PubMed 9087981. Source: MGI

regulation of membrane potential

Inferred from mutant phenotype PubMed 16672662. Source: MGI

righting reflex

Inferred from mutant phenotype PubMed 6285205. Source: MGI

synaptic transmission, glycinergic

Inferred from mutant phenotype PubMed 12809985PubMed 1338094PubMed 16672662. Source: MGI

visual perception

Inferred from mutant phenotype PubMed 1338094. Source: MGI

   Cellular_componentendoplasmic reticulum

Inferred from sequence alignment PubMed 17145751. Source: MGI

external side of plasma membrane

Inferred from sequence alignment PubMed 17145751. Source: MGI

integral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

membrane

Inferred from direct assay PubMed 17145751. Source: MGI

postsynaptic membrane

Inferred from electronic annotation. Source: InterPro

   Molecular_functionbinding

Inferred from physical interaction PubMed 2983837PubMed 6285205. Source: MGI

extracellular-glycine-gated chloride channel activity

Inferred from mutant phenotype PubMed 12809985PubMed 16672662. Source: MGI

glycine binding

Inferred from mutant phenotype PubMed 2983837PubMed 6285205. Source: MGI

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
E9Q3E3 [UniParc].

Last modified April 5, 2011. Version 1.
Checksum: 51EE9D4B1FBA88A3

FASTA30735,307
        10         20         30         40         50         60 
MKFSLAISFF ILMSLLFEDA CAKEKSSKKG KGKKKQYLCP SQQSPEDLAR VPPNSTSNIL 

        70         80         90        100        110        120 
NRLLVSYDPR IRPNFKGIPV DVVVNIFINS FGSIQETTMD YRVNIFLRQK WNDPRLKLPS 

       130        140        150        160        170        180 
DFRGSDALTV DPTMYKCLWK PDLFFANEKS ANFHDVTQEN ILLFIFRDGD VLVSMRLSIT 

       190        200        210        220        230        240 
LSCPLDLTLF PMDTQRCKMQ LESFGYTTDD LRFIWQSGDP VQLEKIALPQ FDIKKEDIEY 

       250        260        270        280        290        300 
GNCTKYYKGT GYYTCVEVIF TLRRQVGFYM MGVYAPTLLI VVLSWLSFWI NPDASAARVP 


LGKLPCF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC121908 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalE9Q3E3.
SMRE9Q3E3. Positions 55-302.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000107743; ENSMUSP00000103372; ENSMUSG00000028020.

Organism-specific databases

MGIMGI:95751. Glrb.

Phylogenomic databases

GeneTreeENSGT00550000074453.

Gene expression databases

ArrayExpressE9Q3E3.
BgeeE9Q3E3.

Family and domain databases

Gene3D2.70.170.10. 1 hit.
InterProIPR008060. Glycine_rcpt_B.
IPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
[Graphical view]
PANTHERPTHR18945. PTHR18945. 1 hit.
PTHR18945:SF29. PTHR18945:SF29. 1 hit.
PfamPF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 1 hit.
[Graphical view]
PRINTSPR01677. GLYRBETA.
PR00252. NRIONCHANNEL.
SUPFAMSSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 1 hit.
TIGRFAMsTIGR00860. LIC. 1 hit.
PROSITEPS00236. NEUROTR_ION_CHANNEL. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio35554978.
SOURCESearch...

Entry information

Entry nameE9Q3E3_MOUSE
AccessionPrimary (citable) accession number: E9Q3E3
Entry history
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: April 16, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)