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E9Q3E3

- E9Q3E3_MOUSE

UniProt

E9Q3E3 - E9Q3E3_MOUSE

Protein
Submitted name:

Glycine receptor subunit beta

Gene

Glrb

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Protein inferred from homologyi
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. binding Source: MGI
    2. extracellular-glycine-gated chloride channel activity Source: MGI
    3. glycine binding Source: MGI

    GO - Biological processi

    1. acrosome reaction Source: MGI
    2. adult walking behavior Source: MGI
    3. chloride transmembrane transport Source: GOC
    4. neuromuscular process Source: MGI
    5. regulation of membrane potential Source: MGI
    6. righting reflex Source: MGI
    7. synaptic transmission, glycinergic Source: MGI
    8. visual perception Source: MGI

    Keywords - Molecular functioni

    Ion channelUniRule annotation

    Keywords - Biological processi

    Ion transport, Transport

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Glycine receptor subunit betaImported
    Gene namesi
    Name:GlrbImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 3

    Organism-specific databases

    MGIiMGI:95751. Glrb.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum Source: MGI
    2. external side of plasma membrane Source: MGI
    3. integral component of membrane Source: UniProtKB-KW
    4. membrane Source: MGI
    5. postsynaptic membrane Source: InterPro

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    ArrayExpressiE9Q3E3.
    BgeeiE9Q3E3.

    Structurei

    3D structure databases

    ProteinModelPortaliE9Q3E3.
    SMRiE9Q3E3. Positions 55-302.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00550000074453.

    Family and domain databases

    Gene3Di2.70.170.10. 1 hit.
    InterProiIPR008060. Glycine_rcpt_B.
    IPR006202. Neur_chan_lig-bd.
    IPR006201. Neur_channel.
    IPR006029. Neurotrans-gated_channel_TM.
    IPR018000. Neurotransmitter_ion_chnl_CS.
    [Graphical view]
    PANTHERiPTHR18945. PTHR18945. 1 hit.
    PTHR18945:SF29. PTHR18945:SF29. 1 hit.
    PfamiPF02931. Neur_chan_LBD. 1 hit.
    PF02932. Neur_chan_memb. 1 hit.
    [Graphical view]
    PRINTSiPR01677. GLYRBETA.
    PR00252. NRIONCHANNEL.
    SUPFAMiSSF63712. SSF63712. 1 hit.
    SSF90112. SSF90112. 1 hit.
    TIGRFAMsiTIGR00860. LIC. 1 hit.
    PROSITEiPS00236. NEUROTR_ION_CHANNEL. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9Q3E3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKFSLAISFF ILMSLLFEDA CAKEKSSKKG KGKKKQYLCP SQQSPEDLAR    50
    VPPNSTSNIL NRLLVSYDPR IRPNFKGIPV DVVVNIFINS FGSIQETTMD 100
    YRVNIFLRQK WNDPRLKLPS DFRGSDALTV DPTMYKCLWK PDLFFANEKS 150
    ANFHDVTQEN ILLFIFRDGD VLVSMRLSIT LSCPLDLTLF PMDTQRCKMQ 200
    LESFGYTTDD LRFIWQSGDP VQLEKIALPQ FDIKKEDIEY GNCTKYYKGT 250
    GYYTCVEVIF TLRRQVGFYM MGVYAPTLLI VVLSWLSFWI NPDASAARVP 300
    LGKLPCF 307
    Length:307
    Mass (Da):35,307
    Last modified:April 5, 2011 - v1
    Checksum:i51EE9D4B1FBA88A3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC121908 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000107743; ENSMUSP00000103372; ENSMUSG00000028020.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC121908 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali E9Q3E3.
    SMRi E9Q3E3. Positions 55-302.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000107743 ; ENSMUSP00000103372 ; ENSMUSG00000028020 .

    Organism-specific databases

    MGIi MGI:95751. Glrb.

    Phylogenomic databases

    GeneTreei ENSGT00550000074453.

    Miscellaneous databases

    NextBioi 35554978.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9Q3E3.
    Bgeei E9Q3E3.

    Family and domain databases

    Gene3Di 2.70.170.10. 1 hit.
    InterProi IPR008060. Glycine_rcpt_B.
    IPR006202. Neur_chan_lig-bd.
    IPR006201. Neur_channel.
    IPR006029. Neurotrans-gated_channel_TM.
    IPR018000. Neurotransmitter_ion_chnl_CS.
    [Graphical view ]
    PANTHERi PTHR18945. PTHR18945. 1 hit.
    PTHR18945:SF29. PTHR18945:SF29. 1 hit.
    Pfami PF02931. Neur_chan_LBD. 1 hit.
    PF02932. Neur_chan_memb. 1 hit.
    [Graphical view ]
    PRINTSi PR01677. GLYRBETA.
    PR00252. NRIONCHANNEL.
    SUPFAMi SSF63712. SSF63712. 1 hit.
    SSF90112. SSF90112. 1 hit.
    TIGRFAMsi TIGR00860. LIC. 1 hit.
    PROSITEi PS00236. NEUROTR_ION_CHANNEL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9Q3E3_MOUSE
    AccessioniPrimary (citable) accession number: E9Q3E3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3