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Protein
Submitted name:

EGF-containing fibulin-like extracellular matrix protein 2

Gene

Efemp2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
EGF-containing fibulin-like extracellular matrix protein 2Imported
Gene namesi
Name:Efemp2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:1891209. Efemp2.

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi139 ↔ 149PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

MaxQBiE9Q2T8.
PaxDbiE9Q2T8.
PeptideAtlasiE9Q2T8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000024909.
ExpressionAtlasiE9Q2T8. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000064719.

Structurei

3D structure databases

SMRiE9Q2T8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 95EGF-likeInterPro annotationAdd BLAST41
Domaini96 – 134EGF-likeInterPro annotationAdd BLAST39
Domaini135 – 170EGF-likeInterPro annotationAdd BLAST36

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG410IR6U. Eukaryota.
ENOG410ZNNG. LUCA.
GeneTreeiENSGT00760000118806.

Family and domain databases

InterProiView protein in InterPro
IPR026823. cEGF.
IPR026824. Efemp2.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_.
PANTHERiPTHR24044:SF379. PTHR24044:SF379. 1 hit.
PfamiView protein in Pfam
PF12662. cEGF. 2 hits.
PF07645. EGF_CA. 1 hit.
SMARTiView protein in SMART
SM00181. EGF. 3 hits.
SM00179. EGF_CA. 3 hits.
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiView protein in PROSITE
PS00010. ASX_HYDROXYL. 3 hits.
PS01186. EGF_2. 3 hits.
PS50026. EGF_3. 3 hits.
PS01187. EGF_CA. 3 hits.

Sequencei

Sequence statusi: Fragment.

E9Q2T8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKCINHYGGY LCLPRSAAVI SDLHGEGPPP PAAHAQQPNP CPQGYEPDEQ
60 70 80 90 100
ESCVDVDECT QALHDCRPSQ DCHNLPGSYQ CTCPDGYRKI GPECVDIDEC
110 120 130 140 150
RYRYCQHRCV NLPGSFRCQC EPGFQLGPNN RSCVDVNECD MGAPCEQRCF
160 170 180 190
NSYGTFLCRC NQGYELHRDG FSCSDIDECG YSSYLCQYRC V
Length:191
Mass (Da):21,397
Last modified:April 5, 2011 - v1
Checksum:i0E3AF23706CFD5EA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei191Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126029 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000167827; ENSMUSP00000127478; ENSMUSG00000024909.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126029 Genomic DNA. No translation available.

3D structure databases

SMRiE9Q2T8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000064719.

Proteomic databases

MaxQBiE9Q2T8.
PaxDbiE9Q2T8.
PeptideAtlasiE9Q2T8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000167827; ENSMUSP00000127478; ENSMUSG00000024909.

Organism-specific databases

MGIiMGI:1891209. Efemp2.

Phylogenomic databases

eggNOGiENOG410IR6U. Eukaryota.
ENOG410ZNNG. LUCA.
GeneTreeiENSGT00760000118806.

Miscellaneous databases

ChiTaRSiEfemp2. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000024909.
ExpressionAtlasiE9Q2T8. baseline and differential.

Family and domain databases

InterProiView protein in InterPro
IPR026823. cEGF.
IPR026824. Efemp2.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_.
PANTHERiPTHR24044:SF379. PTHR24044:SF379. 1 hit.
PfamiView protein in Pfam
PF12662. cEGF. 2 hits.
PF07645. EGF_CA. 1 hit.
SMARTiView protein in SMART
SM00181. EGF. 3 hits.
SM00179. EGF_CA. 3 hits.
SUPFAMiSSF57184. SSF57184. 1 hit.
PROSITEiView protein in PROSITE
PS00010. ASX_HYDROXYL. 3 hits.
PS01186. EGF_2. 3 hits.
PS50026. EGF_3. 3 hits.
PS01187. EGF_CA. 3 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiE9Q2T8_MOUSE
AccessioniPrimary (citable) accession number: E9Q2T8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: February 15, 2017
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.