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Protein
Submitted name:

EGF-containing fibulin-like extracellular matrix protein 2

Gene

Efemp2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
EGF-containing fibulin-like extracellular matrix protein 2Imported
Gene namesi
Name:Efemp2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:1891209 Efemp2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi139 ↔ 149PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

MaxQBiE9Q2T8
PeptideAtlasiE9Q2T8
PRIDEiE9Q2T8

Expressioni

Gene expression databases

BgeeiENSMUSG00000024909
ExpressionAtlasiE9Q2T8 baseline and differential

Structurei

3D structure databases

SMRiE9Q2T8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 95EGF-likeInterPro annotationAdd BLAST41
Domaini96 – 134EGF-likeInterPro annotationAdd BLAST39
Domaini135 – 170EGF-likeInterPro annotationAdd BLAST36

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG410IR6U Eukaryota
ENOG410ZNNG LUCA
GeneTreeiENSGT00760000118806

Family and domain databases

InterProiView protein in InterPro
IPR026823 cEGF
IPR026824 Efemp2
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR037287 Fibulin_3/4/5
IPR009030 Growth_fac_rcpt_cys_sf
PANTHERiPTHR44074 PTHR44074, 1 hit
PTHR44074:SF3 PTHR44074:SF3, 1 hit
PfamiView protein in Pfam
PF12662 cEGF, 2 hits
PF07645 EGF_CA, 1 hit
SMARTiView protein in SMART
SM00181 EGF, 3 hits
SM00179 EGF_CA, 3 hits
SUPFAMiSSF57184 SSF57184, 1 hit
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 3 hits
PS01186 EGF_2, 2 hits
PS50026 EGF_3, 3 hits
PS01187 EGF_CA, 1 hit

Sequencei

Sequence statusi: Fragment.

E9Q2T8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKCINHYGGY LCLPRSAAVI SDLHGEGPPP PAAHAQQPNP CPQGYEPDEQ
60 70 80 90 100
ESCVDVDECT QALHDCRPSQ DCHNLPGSYQ CTCPDGYRKI GPECVDIDEC
110 120 130 140 150
RYRYCQHRCV NLPGSFRCQC EPGFQLGPNN RSCVDVNECD MGAPCEQRCF
160 170 180 190
NSYGTFLCRC NQGYELHRDG FSCSDIDECG YSSYLCQYRC V
Length:191
Mass (Da):21,397
Last modified:April 5, 2011 - v1
Checksum:i0E3AF23706CFD5EA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei191Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126029 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000167827; ENSMUSP00000127478; ENSMUSG00000024909

Similar proteinsi

Entry informationi

Entry nameiE9Q2T8_MOUSE
AccessioniPrimary (citable) accession number: E9Q2T8
Entry historyiIntegrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 23, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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