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Protein

Cation-transporting ATPase

Gene

Atp13a2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, MagnesiumUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cation-transporting ATPaseUniRule annotation (EC:3.6.3.-UniRule annotation)
Gene namesi
Name:Atp13a2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1922022. Atp13a2.

Subcellular locationi

  • Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei251 – 27121HelicalUniRule annotationAdd
BLAST
Transmembranei423 – 44422HelicalUniRule annotationAdd
BLAST
Transmembranei456 – 47924HelicalUniRule annotationAdd
BLAST
Transmembranei925 – 94420HelicalUniRule annotationAdd
BLAST
Transmembranei950 – 96718HelicalUniRule annotationAdd
BLAST
Transmembranei988 – 101831HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiE9Q2A4.

Expressioni

Gene expression databases

BgeeiE9Q2A4.
ExpressionAtlasiE9Q2A4. baseline and differential.
GenevisibleiE9Q2A4. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000039648.

Structurei

3D structure databases

ProteinModelPortaliE9Q2A4.
SMRiE9Q2A4. Positions 249-588, 618-1021.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini258 – 492235E1-E2_ATPaseInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG0208. Eukaryota.
ENOG410XRCA. LUCA.
GeneTreeiENSGT00530000063001.

Family and domain databases

Gene3Di2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006544. P-type_TPase_V.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00122. E1-E2_ATPase. 1 hit.
PF12409. P5-ATPase. 1 hit.
[Graphical view]
PRINTSiPR00120. HATPASE.
SUPFAMiSSF56784. SSF56784. 3 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01494. ATPase_P-type. 2 hits.
TIGR01657. P-ATPase-V. 1 hit.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q2A4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSADSSLLMG STPPSYGTLT TGTSIDPLSS SASSVRLSGY CGSPWRAIGY
60 70 80 90 100
HAAVWMLAGI PWLLFRWKPL WGVRLRLKPC SLAHAETLVI EIKDKEGSSR
110 120 130 140 150
QLFTVQVQTE AVVQGSLELP PQAQAEDGRS QAAVGVTPEG TWQDTSELHR
160 170 180 190 200
QEEAKQVLRY YVLQGQRYVW METQQAFCQV SLLDHGRTCD DVHCSSSGLS
210 220 230 240 250
LQDQATRKTI YGPNVISIPV KSYLQLLADE ALNPYYGFQA FSIALWLADH
260 270 280 290 300
YYWYALCIFL ISAISICLAL YKTRKQSLTL RDMVKLSVRV QVCRPGGEEE
310 320 330 340 350
WVDSSELVPG DCLVLPQEGG VMPCDAALVA GECVVNESSL TGESTPVLKT
360 370 380 390 400
ALPEGPKPYC PETHRRHTLF CGTLILQARA YVGPRVLAVV TRTGFCTAKG
410 420 430 440 450
GLVSSILHPR PISFKFYKHS MKFVAALSVL ALLGTVYSII ILYRNRVPVR
460 470 480 490 500
EIVIRALDLV TVVVPPALPA AMTVCTLYAQ SRLRTQGIFC IHPLRINLGG
510 520 530 540 550
KLRLVCFDKT GTLTEDGLDV MGVVPLKGQV LLPLVPEPCH LPLGPLLRAL
560 570 580 590 600
ATCHALSQLH DTPVGDPMDL KMVESTGWVL EEGPAAGSAP GSQVLVVMRP
610 620 630 640 650
PPGGPRQQEE PPVPVSVLCR FPFSSALQRM DVVVTWPGAT QPEAYVKGSP
660 670 680 690 700
ELVASLCSPE TVPSDFSQVL QSYTAAGYRV VALAGKPLPI APSLAAAQQL
710 720 730 740 750
TRDTVERELS LLGLLVMRNL LKPQTAPVIQ TLRKTGIRTV MVTGDNLQTA
760 770 780 790 800
VTVARACGMV GAQEHLAVIH ATHPEQGQPA ALEFLPTESS AVMNGAKATG
810 820 830 840 850
YPTVPEPQSC HLALSGSTFA VLRKHFPKLL PKVLVQATVF ARMAPEQKTE
860 870 880 890 900
LVCELQRLQY CVGMCGDGAN DCGALKAADV GISLSQAEAS VVSPFTSSMA
910 920 930 940 950
SIECVPTVIR EGRCSLDTSF SVFKYMALYS LTQFISVLIL YTINTNLGDL
960 970 980 990 1000
QFLAIDLVIT TTVAVLMSRT GPALTLVRAR PPGALLSVPV LGSLLLQVAL
1010 1020 1030 1040 1050
VAGIQLGGYF LVIAQPWFVP LNRTVPAPDN LPNYENTVVF SLSGFQYLIL
1060 1070 1080 1090 1100
AAAVSKGAPF RQPLYTNGAP RTEEHCGQLL QATAAGSGRL QLRRRLYAGE
1110
RAGPVSPSLP AVAAA
Length:1,115
Mass (Da):120,156
Last modified:April 5, 2011 - v1
Checksum:i563AC0989D938819
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL645625 Genomic DNA. No translation available.
RefSeqiNP_001157838.1. NM_001164366.1.
UniGeneiMm.205625.

Genome annotation databases

EnsembliENSMUST00000127833; ENSMUSP00000132183; ENSMUSG00000036622.
GeneIDi74772.
UCSCiuc008vno.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL645625 Genomic DNA. No translation available.
RefSeqiNP_001157838.1. NM_001164366.1.
UniGeneiMm.205625.

3D structure databases

ProteinModelPortaliE9Q2A4.
SMRiE9Q2A4. Positions 249-588, 618-1021.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000039648.

Proteomic databases

PaxDbiE9Q2A4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000127833; ENSMUSP00000132183; ENSMUSG00000036622.
GeneIDi74772.
UCSCiuc008vno.2. mouse.

Organism-specific databases

CTDi23400.
MGIiMGI:1922022. Atp13a2.

Phylogenomic databases

eggNOGiKOG0208. Eukaryota.
ENOG410XRCA. LUCA.
GeneTreeiENSGT00530000063001.

Miscellaneous databases

ChiTaRSiAtp13a2. mouse.
NextBioi341604.
SOURCEiSearch...

Gene expression databases

BgeeiE9Q2A4.
ExpressionAtlasiE9Q2A4. baseline and differential.
GenevisibleiE9Q2A4. MM.

Family and domain databases

Gene3Di2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006544. P-type_TPase_V.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00122. E1-E2_ATPase. 1 hit.
PF12409. P5-ATPase. 1 hit.
[Graphical view]
PRINTSiPR00120. HATPASE.
SUPFAMiSSF56784. SSF56784. 3 hits.
SSF81660. SSF81660. 1 hit.
TIGRFAMsiTIGR01494. ATPase_P-type. 2 hits.
TIGR01657. P-ATPase-V. 1 hit.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q2A4_MOUSE
AccessioniPrimary (citable) accession number: E9Q2A4
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: May 11, 2016
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.