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E9Q287

- E9Q287_MOUSE

UniProt

E9Q287 - E9Q287_MOUSE

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Protein
Submitted name:

Protein Adamts3

Gene
Adamts3
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. metalloendopeptidase activity Source: InterPro
  2. peptidase activity Source: MGI
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. protein processing Source: MGI
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_198984. Collagen biosynthesis and modifying enzymes.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Adamts3Imported
Gene namesi
Name:Adamts3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 5

Organism-specific databases

MGIiMGI:3045353. Adamts3.

Subcellular locationi

GO - Cellular componenti

  1. proteinaceous extracellular matrix Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Expressioni

Gene expression databases

ArrayExpressiE9Q287.
BgeeiE9Q287.

Structurei

3D structure databases

ProteinModelPortaliE9Q287.
SMRiE9Q287. Positions 258-825.

Family & Domainsi

Sequence similaritiesi

Contains 1 peptidase M12B domain.UniRule annotation
Contains peptidase M12B domain.SAAS annotations

Phylogenomic databases

GeneTreeiENSGT00740000114846.
KOiK08619.
OMAiAEEWEHC.
OrthoDBiEOG76HQ0N.
TreeFamiTF313537.

Family and domain databases

Gene3Di3.40.390.10. 1 hit.
InterProiIPR010294. ADAM_spacer1.
IPR024079. MetalloPept_cat_dom.
IPR001590. Peptidase_M12B.
IPR013273. Peptidase_M12B_ADAM-TS.
IPR002870. Peptidase_M12B_N.
IPR010909. PLAC.
IPR000884. Thrombospondin_1_rpt.
[Graphical view]
PfamiPF05986. ADAM_spacer1. 1 hit.
PF01562. Pep_M12B_propep. 1 hit.
PF01421. Reprolysin. 1 hit.
PF00090. TSP_1. 4 hits.
[Graphical view]
PRINTSiPR01857. ADAMTSFAMILY.
SMARTiSM00209. TSP1. 4 hits.
[Graphical view]
SUPFAMiSSF82895. SSF82895. 4 hits.
PROSITEiPS50215. ADAM_MEPRO. 1 hit.
PS50900. PLAC. 1 hit.
PS50092. TSP1. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q287-1 [UniParc]FASTAAdd to Basket

« Hide

MVFLSLWLIA ASLVEVRTSA DGQAGTDEMV QIDLPTKRYR EYELVTPVST     50
NLKGHYLSHI LSANHKKRSP RDVSSNSEHL FFNVTAFGRD FHLRLKPNTH 100
FIAPGAVVEW HETAPRPGNT TDPRNSHLHG SASEGSWRSE PLQTSCAYVG 150
DIMDIPGTSV AISNCDGLAG MIKSDDEEYF IEPLERGKQM DEENGRIHVV 200
YKRSAVEQPP RDVSEDVYHR ESDLEGLDDL GTVYSNIGQQ LNKTMRRRRH 250
TGENDYNIEV LLGVDDSVVR FHGKEHVQNY LLTLMNIVNE IYHDESLGVH 300
INVVLVRMIM LGYAKSISLI ERGNPSRSLE NVCRWACQQQ KTDPNHAEHH 350
DHAIFLTRQD FGPAGMQGYA PVTGMCHPVR SCTLNHEDGF SSAFVVAHET 400
GHVLGMEHDG QGNRCGDETA MGSVMAPLVQ AAFHRYHWSR CSGQELKRYI 450
HSYDCLLDDP FEHDWPKLPE LPGINYSMDE QCRFDFGVGY KMCTAFRTFD 500
PCKQLWCSHP DNPYFCKTKK GPPLDGTECA AGKWCYKGHC MWKNANQQKQ 550
DGNWGSWTKF GSCSRTCGTG VRFRTRQCNN PTPINGGQDC PGVNFEYQLC 600
NTEECQKHFE DFRAQQCQQR NSHFDYQNTK HHWLPHEHPD SKKRCHLYCQ 650
SKETGDVAYM KQLVHDGTRC SYKDPYSICV RGECVKVGCD REIGSNKVED 700
KCGVCGGDNS HCRTVKGTFT RTPRKLGKTR GAFVLPKGAR NISLAETRET 750
KNVLAIKNQA TGHYILNGKG EEAKSRTFID LGVEWDYNIE DDIETLHTDG 800
PLHDPVIVLI IPQENDTRSS LTYKYIIHED SVPTINSNNV IQEELDTFEW 850
ALKSWSQCSE PCGGGFQYTK YGCRRKSDSK MVHRSFCEVN KKPKPIRRMC 900
NIQECTHPVW AADEWEHCSR SCGSSGNQLR TVRCLQPLQD GTNRSVHSKY 950
CLGDRPESRR PCNRVPCPAQ WKTGSWNECS VTCGEGTEVR QVLCRTGDHC 1000
DGEKPESVRP CQLPPCNDEP CLGDKSIFCQ MEVLARYCSI PGYNKLCCES 1050
CSKRSGTLPP PYLQEAAEIH SDAIFGPSDL PRSLVMPTPF LPSSSGTRAE 1100
KKSLSSFSSM ANPNADAAFR ASSRASADFP RKRAHQAGRK TLESVPSSSS 1150
IKTDHLRPAS PVAAAPSPAI SDSIGASPQT RTPKKDDAKS VSRRHPTRST 1200
ASER 1204
Length:1,204
Mass (Da):135,185
Last modified:April 5, 2011 - v1
Checksum:i9B261F73622A1D75
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC102039 Genomic DNA. No translation available.
AC102056 Genomic DNA. No translation available.
AC156611 Genomic DNA. No translation available.
RefSeqiNP_808540.2. NM_177872.2.
UniGeneiMm.133062.

Genome annotation databases

EnsembliENSMUST00000163159; ENSMUSP00000132219; ENSMUSG00000043635.
GeneIDi330119.
KEGGimmu:330119.
UCSCiuc012dyf.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC102039 Genomic DNA. No translation available.
AC102056 Genomic DNA. No translation available.
AC156611 Genomic DNA. No translation available.
RefSeqi NP_808540.2. NM_177872.2.
UniGenei Mm.133062.

3D structure databases

ProteinModelPortali E9Q287.
SMRi E9Q287. Positions 258-825.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

DNASUi 330119.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000163159 ; ENSMUSP00000132219 ; ENSMUSG00000043635 .
GeneIDi 330119.
KEGGi mmu:330119.
UCSCi uc012dyf.1. mouse.

Organism-specific databases

CTDi 9508.
MGIi MGI:3045353. Adamts3.

Phylogenomic databases

GeneTreei ENSGT00740000114846.
KOi K08619.
OMAi AEEWEHC.
OrthoDBi EOG76HQ0N.
TreeFami TF313537.

Enzyme and pathway databases

Reactomei REACT_198984. Collagen biosynthesis and modifying enzymes.

Miscellaneous databases

NextBioi 399154.
PROi E9Q287.
SOURCEi Search...

Gene expression databases

ArrayExpressi E9Q287.
Bgeei E9Q287.

Family and domain databases

Gene3Di 3.40.390.10. 1 hit.
InterProi IPR010294. ADAM_spacer1.
IPR024079. MetalloPept_cat_dom.
IPR001590. Peptidase_M12B.
IPR013273. Peptidase_M12B_ADAM-TS.
IPR002870. Peptidase_M12B_N.
IPR010909. PLAC.
IPR000884. Thrombospondin_1_rpt.
[Graphical view ]
Pfami PF05986. ADAM_spacer1. 1 hit.
PF01562. Pep_M12B_propep. 1 hit.
PF01421. Reprolysin. 1 hit.
PF00090. TSP_1. 4 hits.
[Graphical view ]
PRINTSi PR01857. ADAMTSFAMILY.
SMARTi SM00209. TSP1. 4 hits.
[Graphical view ]
SUPFAMi SSF82895. SSF82895. 4 hits.
PROSITEi PS50215. ADAM_MEPRO. 1 hit.
PS50900. PLAC. 1 hit.
PS50092. TSP1. 4 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q287_MOUSE
AccessioniPrimary (citable) accession number: E9Q287
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: September 3, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi