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E9Q287

- E9Q287_MOUSE

UniProt

E9Q287 - E9Q287_MOUSE

Protein
Submitted name:

Protein Adamts3

Gene

Adamts3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. metalloendopeptidase activity Source: InterPro
    2. peptidase activity Source: MGI
    3. zinc ion binding Source: InterPro

    GO - Biological processi

    1. protein processing Source: MGI

    Enzyme and pathway databases

    ReactomeiREACT_198984. Collagen biosynthesis and modifying enzymes.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein Adamts3Imported
    Gene namesi
    Name:Adamts3Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 5

    Organism-specific databases

    MGIiMGI:3045353. Adamts3.

    Subcellular locationi

    GO - Cellular componenti

    1. proteinaceous extracellular matrix Source: InterPro

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Expressioni

    Gene expression databases

    ArrayExpressiE9Q287.
    BgeeiE9Q287.

    Structurei

    3D structure databases

    ProteinModelPortaliE9Q287.
    SMRiE9Q287. Positions 258-825.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 peptidase M12B domain.UniRule annotation
    Contains peptidase M12B domain.SAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00740000114846.
    KOiK08619.
    OMAiAEEWEHC.
    OrthoDBiEOG76HQ0N.
    TreeFamiTF313537.

    Family and domain databases

    Gene3Di3.40.390.10. 1 hit.
    InterProiIPR010294. ADAM_spacer1.
    IPR024079. MetalloPept_cat_dom.
    IPR001590. Peptidase_M12B.
    IPR013273. Peptidase_M12B_ADAM-TS.
    IPR002870. Peptidase_M12B_N.
    IPR010909. PLAC.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view]
    PfamiPF05986. ADAM_spacer1. 1 hit.
    PF01562. Pep_M12B_propep. 1 hit.
    PF01421. Reprolysin. 1 hit.
    PF00090. TSP_1. 4 hits.
    [Graphical view]
    PRINTSiPR01857. ADAMTSFAMILY.
    SMARTiSM00209. TSP1. 4 hits.
    [Graphical view]
    SUPFAMiSSF82895. SSF82895. 4 hits.
    PROSITEiPS50215. ADAM_MEPRO. 1 hit.
    PS50900. PLAC. 1 hit.
    PS50092. TSP1. 4 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9Q287-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVFLSLWLIA ASLVEVRTSA DGQAGTDEMV QIDLPTKRYR EYELVTPVST     50
    NLKGHYLSHI LSANHKKRSP RDVSSNSEHL FFNVTAFGRD FHLRLKPNTH 100
    FIAPGAVVEW HETAPRPGNT TDPRNSHLHG SASEGSWRSE PLQTSCAYVG 150
    DIMDIPGTSV AISNCDGLAG MIKSDDEEYF IEPLERGKQM DEENGRIHVV 200
    YKRSAVEQPP RDVSEDVYHR ESDLEGLDDL GTVYSNIGQQ LNKTMRRRRH 250
    TGENDYNIEV LLGVDDSVVR FHGKEHVQNY LLTLMNIVNE IYHDESLGVH 300
    INVVLVRMIM LGYAKSISLI ERGNPSRSLE NVCRWACQQQ KTDPNHAEHH 350
    DHAIFLTRQD FGPAGMQGYA PVTGMCHPVR SCTLNHEDGF SSAFVVAHET 400
    GHVLGMEHDG QGNRCGDETA MGSVMAPLVQ AAFHRYHWSR CSGQELKRYI 450
    HSYDCLLDDP FEHDWPKLPE LPGINYSMDE QCRFDFGVGY KMCTAFRTFD 500
    PCKQLWCSHP DNPYFCKTKK GPPLDGTECA AGKWCYKGHC MWKNANQQKQ 550
    DGNWGSWTKF GSCSRTCGTG VRFRTRQCNN PTPINGGQDC PGVNFEYQLC 600
    NTEECQKHFE DFRAQQCQQR NSHFDYQNTK HHWLPHEHPD SKKRCHLYCQ 650
    SKETGDVAYM KQLVHDGTRC SYKDPYSICV RGECVKVGCD REIGSNKVED 700
    KCGVCGGDNS HCRTVKGTFT RTPRKLGKTR GAFVLPKGAR NISLAETRET 750
    KNVLAIKNQA TGHYILNGKG EEAKSRTFID LGVEWDYNIE DDIETLHTDG 800
    PLHDPVIVLI IPQENDTRSS LTYKYIIHED SVPTINSNNV IQEELDTFEW 850
    ALKSWSQCSE PCGGGFQYTK YGCRRKSDSK MVHRSFCEVN KKPKPIRRMC 900
    NIQECTHPVW AADEWEHCSR SCGSSGNQLR TVRCLQPLQD GTNRSVHSKY 950
    CLGDRPESRR PCNRVPCPAQ WKTGSWNECS VTCGEGTEVR QVLCRTGDHC 1000
    DGEKPESVRP CQLPPCNDEP CLGDKSIFCQ MEVLARYCSI PGYNKLCCES 1050
    CSKRSGTLPP PYLQEAAEIH SDAIFGPSDL PRSLVMPTPF LPSSSGTRAE 1100
    KKSLSSFSSM ANPNADAAFR ASSRASADFP RKRAHQAGRK TLESVPSSSS 1150
    IKTDHLRPAS PVAAAPSPAI SDSIGASPQT RTPKKDDAKS VSRRHPTRST 1200
    ASER 1204
    Length:1,204
    Mass (Da):135,185
    Last modified:April 5, 2011 - v1
    Checksum:i9B261F73622A1D75
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC102039 Genomic DNA. No translation available.
    AC102056 Genomic DNA. No translation available.
    AC156611 Genomic DNA. No translation available.
    RefSeqiNP_808540.2. NM_177872.2.
    UniGeneiMm.133062.

    Genome annotation databases

    EnsembliENSMUST00000163159; ENSMUSP00000132219; ENSMUSG00000043635.
    GeneIDi330119.
    KEGGimmu:330119.
    UCSCiuc012dyf.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC102039 Genomic DNA. No translation available.
    AC102056 Genomic DNA. No translation available.
    AC156611 Genomic DNA. No translation available.
    RefSeqi NP_808540.2. NM_177872.2.
    UniGenei Mm.133062.

    3D structure databases

    ProteinModelPortali E9Q287.
    SMRi E9Q287. Positions 258-825.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    DNASUi 330119.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000163159 ; ENSMUSP00000132219 ; ENSMUSG00000043635 .
    GeneIDi 330119.
    KEGGi mmu:330119.
    UCSCi uc012dyf.1. mouse.

    Organism-specific databases

    CTDi 9508.
    MGIi MGI:3045353. Adamts3.

    Phylogenomic databases

    GeneTreei ENSGT00740000114846.
    KOi K08619.
    OMAi AEEWEHC.
    OrthoDBi EOG76HQ0N.
    TreeFami TF313537.

    Enzyme and pathway databases

    Reactomei REACT_198984. Collagen biosynthesis and modifying enzymes.

    Miscellaneous databases

    NextBioi 399154.
    PROi E9Q287.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9Q287.
    Bgeei E9Q287.

    Family and domain databases

    Gene3Di 3.40.390.10. 1 hit.
    InterProi IPR010294. ADAM_spacer1.
    IPR024079. MetalloPept_cat_dom.
    IPR001590. Peptidase_M12B.
    IPR013273. Peptidase_M12B_ADAM-TS.
    IPR002870. Peptidase_M12B_N.
    IPR010909. PLAC.
    IPR000884. Thrombospondin_1_rpt.
    [Graphical view ]
    Pfami PF05986. ADAM_spacer1. 1 hit.
    PF01562. Pep_M12B_propep. 1 hit.
    PF01421. Reprolysin. 1 hit.
    PF00090. TSP_1. 4 hits.
    [Graphical view ]
    PRINTSi PR01857. ADAMTSFAMILY.
    SMARTi SM00209. TSP1. 4 hits.
    [Graphical view ]
    SUPFAMi SSF82895. SSF82895. 4 hits.
    PROSITEi PS50215. ADAM_MEPRO. 1 hit.
    PS50900. PLAC. 1 hit.
    PS50092. TSP1. 4 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9Q287_MOUSE
    AccessioniPrimary (citable) accession number: E9Q287
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3