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Protein
Submitted name:

Protein Abcc4

Gene

Abcc4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_293350. ABC-family proteins mediated transport.
REACT_307071. Platelet degranulation.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Abcc4Imported
Gene namesi
Name:Abcc4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:2443111. Abcc4.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiE9Q236.
PRIDEiE9Q236.

Expressioni

Gene expression databases

BgeeiE9Q236.
ExpressionAtlasiE9Q236. baseline and differential.
GenevisibleiE9Q236. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000042186.

Structurei

3D structure databases

ProteinModelPortaliE9Q236.
SMRiE9Q236. Positions 110-689, 761-1280.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ABC transporter superfamily.UniRule annotation
Contains ABC transmembrane type-1 domains.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00770000120479.
InParanoidiE9Q236.
KOiK05673.
OMAiFQLCICQ.
OrthoDBiEOG7MWGW0.
PhylomeDBiE9Q236.
TreeFamiTF105202.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR030240. ABCC4.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24223:SF205. PTHR24223:SF205. 1 hit.
PfamiPF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiPS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q236-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPVHTEVKP NPLQDANLCS RVFFWWLNPL FKTGHKRRLE EDDMFSVLPE
60 70 80 90 100
DRSKHLGEEL QRYWDKELLR AKKDSRKPSL TKAIIKCYWK SYLILGIFTL
110 120 130 140 150
IEEGTRVVQP LFLGKIIEYF EKYDPDDSVA LHTAYGYAAV LSMCTLILAI
160 170 180 190 200
LHHLYFYHVQ CAGMRLRVAM CHMIYRKALR LSNSAMGKTT TGQIVNLLSN
210 220 230 240 250
DVNKFDQVTI FLHFLWAGPL QAIAVTVLLW VEIGISCLAG LAVLVILLPL
260 270 280 290 300
QSCIGKLFSS LRSKTAAFTD ARIRTMNEVI TGMRIIKMYA WEKSFADLIA
310 320 330 340 350
NLRKKEISKI LGSSYLRGMN MASFFIANKV ILFVTFTSYV LLGNEITASH
360 370 380 390 400
VFVAMTLYGA VRLTVTLFFP SAIERGSEAI VSIRRIKNFL LLDELPQRKA
410 420 430 440 450
HVPSDGKAIV HVQDFTAFWD KALDSPTLQG LSFIARPGEL LAVVGPVGAG
460 470 480 490 500
KSSLLSAVLG ELPPASGLVS VHGRIAYVSQ QPWVFSGTVR SNILFGKKYE
510 520 530 540 550
KERYEKVIKA CALKKDLQLL EDGDLTVIGD RGATLSGGQK ARVNLARAVY
560 570 580 590 600
QDADIYLLDD PLSAVDAEVG KHLFQLCICQ ALHEKITILV THQLQYLKAA
610 620 630 640 650
SHILILKDGE MVQKGTYTEF LKSGVDFGSL LKKENEEAEP STAPGTPTLR
660 670 680 690 700
KRTFSEASIW SQQSSRPSLK DGAPEGQDAE NTQAVQPEES RSEGRIGFKA
710 720 730 740 750
YKNYFSAGAS WFFIIFLVLL NMVGQVFYVL QDWWLSHWAN KQGALNNTRN
760 770 780 790 800
ANGNITETLD LSWYLGIYAG LTAVTVLFGI ARSLLVFYIL VNASQTLHNR
810 820 830 840 850
MFESILKAPV LFFDRNPIGR ILNRFSKDIG HMDDLLPLTF LDFIQTLLLV
860 870 880 890 900
VSVIAVAAAV IPWILIPLVP LSVVFLVLRR YFLETSRDVK RLESTTRSPV
910 920 930 940 950
FSHLSSSLQG LWTIRAYKAE ERCQELFDAH QDLHSEAWFL FLTTSRWFAV
960 970 980 990 1000
RLDAICAIFV IVVAFGSLVL AKTLNAGQVG LALSYALTLM GMFQWSVRQS
1010 1020 1030 1040 1050
AEVENMMISV ERVIEYTDLE KEAPWECKKR PPPGWPHEGV IVFDNVNFTY
1060 1070 1080 1090 1100
SLDGPLVLKH LTALIKSREK VGIVGRTGAG KSSLISALFR LSEPEGKIWI
1110 1120 1130 1140 1150
DKILTTEIGL HDLRKKMSII PQEPVLFTGT MRKNLDPFNE HTDEELWRAL
1160 1170 1180 1190 1200
EEVQLKEAIE DLPGKMDTEL AESGSNFSVG QRQLVCLARA ILKNNRILII
1210 1220 1230 1240 1250
DEATANVDPR TDELIQQKIR EKFAQCTVLT IAHRLNTIID SDKIMVLDSG
1260 1270 1280 1290 1300
RLKEYDEPYV LLQNPESLFY KMVQQLGKGE AAALTETAKQ VYFRRNYPDI
1310 1320
TFTSPAVMNT SNGQPSALTI FETAL
Length:1,325
Mass (Da):148,888
Last modified:April 5, 2011 - v1
Checksum:i3F1469648CBE9699
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154419 Genomic DNA. No translation available.
AC167668 Genomic DNA. No translation available.
CT025694 Genomic DNA. No translation available.
RefSeqiNP_001028508.2. NM_001033336.3.
UniGeneiMm.40537.

Genome annotation databases

EnsembliENSMUST00000036554; ENSMUSP00000042186; ENSMUSG00000032849.
GeneIDi239273.
KEGGimmu:239273.
UCSCiuc007uyv.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154419 Genomic DNA. No translation available.
AC167668 Genomic DNA. No translation available.
CT025694 Genomic DNA. No translation available.
RefSeqiNP_001028508.2. NM_001033336.3.
UniGeneiMm.40537.

3D structure databases

ProteinModelPortaliE9Q236.
SMRiE9Q236. Positions 110-689, 761-1280.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000042186.

Proteomic databases

MaxQBiE9Q236.
PRIDEiE9Q236.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000036554; ENSMUSP00000042186; ENSMUSG00000032849.
GeneIDi239273.
KEGGimmu:239273.
UCSCiuc007uyv.2. mouse.

Organism-specific databases

CTDi10257.
MGIiMGI:2443111. Abcc4.

Phylogenomic databases

GeneTreeiENSGT00770000120479.
InParanoidiE9Q236.
KOiK05673.
OMAiFQLCICQ.
OrthoDBiEOG7MWGW0.
PhylomeDBiE9Q236.
TreeFamiTF105202.

Enzyme and pathway databases

ReactomeiREACT_293350. ABC-family proteins mediated transport.
REACT_307071. Platelet degranulation.

Miscellaneous databases

NextBioi384052.
PROiE9Q236.
SOURCEiSearch...

Gene expression databases

BgeeiE9Q236.
ExpressionAtlasiE9Q236. baseline and differential.
GenevisibleiE9Q236. MM.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR030240. ABCC4.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR24223:SF205. PTHR24223:SF205. 1 hit.
PfamiPF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiPS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q236_MOUSE
AccessioniPrimary (citable) accession number: E9Q236
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: June 24, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.