Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

E9Q236

- E9Q236_MOUSE

UniProt

E9Q236 - E9Q236_MOUSE

Protein
Submitted name:

Protein Abcc4

Gene

Abcc4

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 32 (01 Oct 2014)
      Sequence version 1 (05 Apr 2011)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. ATPase activity, coupled to transmembrane movement of substances Source: InterPro
    2. ATP binding Source: UniProtKB-KW
    3. drug transmembrane transporter activity Source: MGI

    GO - Biological processi

    1. drug transmembrane transport Source: MGI

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein Abcc4Imported
    Gene namesi
    Name:Abcc4Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 14

    Organism-specific databases

    MGIiMGI:2443111. Abcc4.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: InterPro
    2. plasma membrane Source: Ensembl
    3. platelet dense granule membrane Source: Ensembl

    PTM / Processingi

    Proteomic databases

    MaxQBiE9Q236.
    PRIDEiE9Q236.

    Expressioni

    Gene expression databases

    ArrayExpressiE9Q236.
    BgeeiE9Q236.

    Structurei

    3D structure databases

    ProteinModelPortaliE9Q236.
    SMRiE9Q236. Positions 110-689, 697-1280.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ABC transporter superfamily.UniRule annotation
    Contains ABC transmembrane type-1 domains.SAAS annotation

    Keywords - Domaini

    RepeatSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117309.
    KOiK05673.
    OMAiCAMFVII.
    OrthoDBiEOG7MWGW0.
    PhylomeDBiE9Q236.
    TreeFamiTF105202.

    Family and domain databases

    Gene3Di3.40.50.300. 2 hits.
    InterProiIPR003593. AAA+_ATPase.
    IPR011527. ABC1_TM_dom.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR001140. ABC_transptr_TM_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00664. ABC_membrane. 2 hits.
    PF00005. ABC_tran. 2 hits.
    [Graphical view]
    SMARTiSM00382. AAA. 2 hits.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 2 hits.
    SSF90123. SSF90123. 2 hits.
    PROSITEiPS50929. ABC_TM1F. 2 hits.
    PS00211. ABC_TRANSPORTER_1. 2 hits.
    PS50893. ABC_TRANSPORTER_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    E9Q236-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLPVHTEVKP NPLQDANLCS RVFFWWLNPL FKTGHKRRLE EDDMFSVLPE     50
    DRSKHLGEEL QRYWDKELLR AKKDSRKPSL TKAIIKCYWK SYLILGIFTL 100
    IEEGTRVVQP LFLGKIIEYF EKYDPDDSVA LHTAYGYAAV LSMCTLILAI 150
    LHHLYFYHVQ CAGMRLRVAM CHMIYRKALR LSNSAMGKTT TGQIVNLLSN 200
    DVNKFDQVTI FLHFLWAGPL QAIAVTVLLW VEIGISCLAG LAVLVILLPL 250
    QSCIGKLFSS LRSKTAAFTD ARIRTMNEVI TGMRIIKMYA WEKSFADLIA 300
    NLRKKEISKI LGSSYLRGMN MASFFIANKV ILFVTFTSYV LLGNEITASH 350
    VFVAMTLYGA VRLTVTLFFP SAIERGSEAI VSIRRIKNFL LLDELPQRKA 400
    HVPSDGKAIV HVQDFTAFWD KALDSPTLQG LSFIARPGEL LAVVGPVGAG 450
    KSSLLSAVLG ELPPASGLVS VHGRIAYVSQ QPWVFSGTVR SNILFGKKYE 500
    KERYEKVIKA CALKKDLQLL EDGDLTVIGD RGATLSGGQK ARVNLARAVY 550
    QDADIYLLDD PLSAVDAEVG KHLFQLCICQ ALHEKITILV THQLQYLKAA 600
    SHILILKDGE MVQKGTYTEF LKSGVDFGSL LKKENEEAEP STAPGTPTLR 650
    KRTFSEASIW SQQSSRPSLK DGAPEGQDAE NTQAVQPEES RSEGRIGFKA 700
    YKNYFSAGAS WFFIIFLVLL NMVGQVFYVL QDWWLSHWAN KQGALNNTRN 750
    ANGNITETLD LSWYLGIYAG LTAVTVLFGI ARSLLVFYIL VNASQTLHNR 800
    MFESILKAPV LFFDRNPIGR ILNRFSKDIG HMDDLLPLTF LDFIQTLLLV 850
    VSVIAVAAAV IPWILIPLVP LSVVFLVLRR YFLETSRDVK RLESTTRSPV 900
    FSHLSSSLQG LWTIRAYKAE ERCQELFDAH QDLHSEAWFL FLTTSRWFAV 950
    RLDAICAIFV IVVAFGSLVL AKTLNAGQVG LALSYALTLM GMFQWSVRQS 1000
    AEVENMMISV ERVIEYTDLE KEAPWECKKR PPPGWPHEGV IVFDNVNFTY 1050
    SLDGPLVLKH LTALIKSREK VGIVGRTGAG KSSLISALFR LSEPEGKIWI 1100
    DKILTTEIGL HDLRKKMSII PQEPVLFTGT MRKNLDPFNE HTDEELWRAL 1150
    EEVQLKEAIE DLPGKMDTEL AESGSNFSVG QRQLVCLARA ILKNNRILII 1200
    DEATANVDPR TDELIQQKIR EKFAQCTVLT IAHRLNTIID SDKIMVLDSG 1250
    RLKEYDEPYV LLQNPESLFY KMVQQLGKGE AAALTETAKQ VYFRRNYPDI 1300
    TFTSPAVMNT SNGQPSALTI FETAL 1325
    Length:1,325
    Mass (Da):148,888
    Last modified:April 5, 2011 - v1
    Checksum:i3F1469648CBE9699
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC154419 Genomic DNA. No translation available.
    AC167668 Genomic DNA. No translation available.
    CT025694 Genomic DNA. No translation available.
    RefSeqiNP_001028508.2. NM_001033336.3.
    UniGeneiMm.40537.

    Genome annotation databases

    EnsembliENSMUST00000036554; ENSMUSP00000042186; ENSMUSG00000032849.
    GeneIDi239273.
    KEGGimmu:239273.
    UCSCiuc007uyv.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC154419 Genomic DNA. No translation available.
    AC167668 Genomic DNA. No translation available.
    CT025694 Genomic DNA. No translation available.
    RefSeqi NP_001028508.2. NM_001033336.3.
    UniGenei Mm.40537.

    3D structure databases

    ProteinModelPortali E9Q236.
    SMRi E9Q236. Positions 110-689, 697-1280.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    MaxQBi E9Q236.
    PRIDEi E9Q236.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000036554 ; ENSMUSP00000042186 ; ENSMUSG00000032849 .
    GeneIDi 239273.
    KEGGi mmu:239273.
    UCSCi uc007uyv.2. mouse.

    Organism-specific databases

    CTDi 10257.
    MGIi MGI:2443111. Abcc4.

    Phylogenomic databases

    GeneTreei ENSGT00750000117309.
    KOi K05673.
    OMAi CAMFVII.
    OrthoDBi EOG7MWGW0.
    PhylomeDBi E9Q236.
    TreeFami TF105202.

    Miscellaneous databases

    NextBioi 384052.
    PROi E9Q236.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi E9Q236.
    Bgeei E9Q236.

    Family and domain databases

    Gene3Di 3.40.50.300. 2 hits.
    InterProi IPR003593. AAA+_ATPase.
    IPR011527. ABC1_TM_dom.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR001140. ABC_transptr_TM_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00664. ABC_membrane. 2 hits.
    PF00005. ABC_tran. 2 hits.
    [Graphical view ]
    SMARTi SM00382. AAA. 2 hits.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 2 hits.
    SSF90123. SSF90123. 2 hits.
    PROSITEi PS50929. ABC_TM1F. 2 hits.
    PS00211. ABC_TRANSPORTER_1. 2 hits.
    PS50893. ABC_TRANSPORTER_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
      Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    4. Ensembl
      Submitted (MAY-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiE9Q236_MOUSE
    AccessioniPrimary (citable) accession number: E9Q236
    Entry historyi
    Integrated into UniProtKB/TrEMBL: April 5, 2011
    Last sequence update: April 5, 2011
    Last modified: October 1, 2014
    This is version 32 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3