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E9Q236

- E9Q236_MOUSE

UniProt

E9Q236 - E9Q236_MOUSE

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Protein
Submitted name: Protein Abcc4
Gene
Abcc4
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. ATPase activity, coupled to transmembrane movement of substances Source: InterPro
  3. drug transmembrane transporter activity Source: MGI

GO - Biological processi

  1. drug transmembrane transport Source: MGI
Complete GO annotation...

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Abcc4Imported
Gene namesi
Name:Abcc4Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 14

Organism-specific databases

MGIiMGI:2443111. Abcc4.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
  2. plasma membrane Source: Ensembl
  3. platelet dense granule membrane Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiE9Q236.
PRIDEiE9Q236.

Expressioni

Gene expression databases

ArrayExpressiE9Q236.
BgeeiE9Q236.

Structurei

3D structure databases

ProteinModelPortaliE9Q236.
SMRiE9Q236. Positions 110-689, 713-1280.

Family & Domainsi

Sequence similaritiesi

Belongs to the ABC transporter superfamily.UniRule annotation
Contains ABC transmembrane type-1 domains.SAAS annotations
Contains ABC transmembrane type-domains.SAAS annotations

Keywords - Domaini

RepeatSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00750000117309.
KOiK05673.
OMAiCAMFVII.
OrthoDBiEOG7MWGW0.
PhylomeDBiE9Q236.
TreeFamiTF105202.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR001140. ABC_transptr_TM_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiPS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

E9Q236-1 [UniParc]FASTAAdd to Basket

« Hide

MLPVHTEVKP NPLQDANLCS RVFFWWLNPL FKTGHKRRLE EDDMFSVLPE     50
DRSKHLGEEL QRYWDKELLR AKKDSRKPSL TKAIIKCYWK SYLILGIFTL 100
IEEGTRVVQP LFLGKIIEYF EKYDPDDSVA LHTAYGYAAV LSMCTLILAI 150
LHHLYFYHVQ CAGMRLRVAM CHMIYRKALR LSNSAMGKTT TGQIVNLLSN 200
DVNKFDQVTI FLHFLWAGPL QAIAVTVLLW VEIGISCLAG LAVLVILLPL 250
QSCIGKLFSS LRSKTAAFTD ARIRTMNEVI TGMRIIKMYA WEKSFADLIA 300
NLRKKEISKI LGSSYLRGMN MASFFIANKV ILFVTFTSYV LLGNEITASH 350
VFVAMTLYGA VRLTVTLFFP SAIERGSEAI VSIRRIKNFL LLDELPQRKA 400
HVPSDGKAIV HVQDFTAFWD KALDSPTLQG LSFIARPGEL LAVVGPVGAG 450
KSSLLSAVLG ELPPASGLVS VHGRIAYVSQ QPWVFSGTVR SNILFGKKYE 500
KERYEKVIKA CALKKDLQLL EDGDLTVIGD RGATLSGGQK ARVNLARAVY 550
QDADIYLLDD PLSAVDAEVG KHLFQLCICQ ALHEKITILV THQLQYLKAA 600
SHILILKDGE MVQKGTYTEF LKSGVDFGSL LKKENEEAEP STAPGTPTLR 650
KRTFSEASIW SQQSSRPSLK DGAPEGQDAE NTQAVQPEES RSEGRIGFKA 700
YKNYFSAGAS WFFIIFLVLL NMVGQVFYVL QDWWLSHWAN KQGALNNTRN 750
ANGNITETLD LSWYLGIYAG LTAVTVLFGI ARSLLVFYIL VNASQTLHNR 800
MFESILKAPV LFFDRNPIGR ILNRFSKDIG HMDDLLPLTF LDFIQTLLLV 850
VSVIAVAAAV IPWILIPLVP LSVVFLVLRR YFLETSRDVK RLESTTRSPV 900
FSHLSSSLQG LWTIRAYKAE ERCQELFDAH QDLHSEAWFL FLTTSRWFAV 950
RLDAICAIFV IVVAFGSLVL AKTLNAGQVG LALSYALTLM GMFQWSVRQS 1000
AEVENMMISV ERVIEYTDLE KEAPWECKKR PPPGWPHEGV IVFDNVNFTY 1050
SLDGPLVLKH LTALIKSREK VGIVGRTGAG KSSLISALFR LSEPEGKIWI 1100
DKILTTEIGL HDLRKKMSII PQEPVLFTGT MRKNLDPFNE HTDEELWRAL 1150
EEVQLKEAIE DLPGKMDTEL AESGSNFSVG QRQLVCLARA ILKNNRILII 1200
DEATANVDPR TDELIQQKIR EKFAQCTVLT IAHRLNTIID SDKIMVLDSG 1250
RLKEYDEPYV LLQNPESLFY KMVQQLGKGE AAALTETAKQ VYFRRNYPDI 1300
TFTSPAVMNT SNGQPSALTI FETAL 1325
Length:1,325
Mass (Da):148,888
Last modified:April 5, 2011 - v1
Checksum:i3F1469648CBE9699
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC154419 Genomic DNA. No translation available.
AC167668 Genomic DNA. No translation available.
CT025694 Genomic DNA. No translation available.
RefSeqiNP_001028508.2. NM_001033336.3.
UniGeneiMm.40537.

Genome annotation databases

EnsembliENSMUST00000036554; ENSMUSP00000042186; ENSMUSG00000032849.
GeneIDi239273.
KEGGimmu:239273.
UCSCiuc007uyv.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC154419 Genomic DNA. No translation available.
AC167668 Genomic DNA. No translation available.
CT025694 Genomic DNA. No translation available.
RefSeqi NP_001028508.2. NM_001033336.3.
UniGenei Mm.40537.

3D structure databases

ProteinModelPortali E9Q236.
SMRi E9Q236. Positions 110-689, 713-1280.
ModBasei Search...
MobiDBi Search...

Proteomic databases

MaxQBi E9Q236.
PRIDEi E9Q236.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000036554 ; ENSMUSP00000042186 ; ENSMUSG00000032849 .
GeneIDi 239273.
KEGGi mmu:239273.
UCSCi uc007uyv.2. mouse.

Organism-specific databases

CTDi 10257.
MGIi MGI:2443111. Abcc4.

Phylogenomic databases

GeneTreei ENSGT00750000117309.
KOi K05673.
OMAi CAMFVII.
OrthoDBi EOG7MWGW0.
PhylomeDBi E9Q236.
TreeFami TF105202.

Miscellaneous databases

NextBioi 384052.
PROi E9Q236.
SOURCEi Search...

Gene expression databases

ArrayExpressi E9Q236.
Bgeei E9Q236.

Family and domain databases

Gene3Di 3.40.50.300. 2 hits.
InterProi IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR001140. ABC_transptr_TM_dom.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view ]
SMARTi SM00382. AAA. 2 hits.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEi PS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. "The phagosomal proteome in interferon-gamma-activated macrophages."
    Trost M., English L., Lemieux S., Courcelles M., Desjardins M., Thibault P.
    Immunity 30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Ensembl
    Submitted (MAY-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiE9Q236_MOUSE
AccessioniPrimary (citable) accession number: E9Q236
Entry historyi
Integrated into UniProtKB/TrEMBL: April 5, 2011
Last sequence update: April 5, 2011
Last modified: July 9, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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